Marie Eikemo

Postdoctoral Fellow - Department of Psychology
Image of Marie Eikemo
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Available hours By agreement
Visiting address Forskningsveien 3A Harald Schjelderups hus 0373 OSLO
Postal address Postboks 1094 Blindern 0317 OSLO
Other affiliations Department of Education (Student)

Academic interests

  • The neuroscience of reward and anhedonia

  • Motivation and hedonic experience of food, music, social cues and perception.

  • Value-based decision-making

  • The human opioid system (including the endorphin system)

  • Factors influencing pain, stress and affect

  • Effects of long-term treatment with opioid drugs in patients with chronic pain and opioid use disorder, and children prenatally exposed to opioids

I have a background in cognitive psychology, neuroscience with a specialization in judgement and decision making, psychopharmacology and reward processes. Throughout my MA, PhD and first postdoc I have been working on projects designed to investigate the role of the µ-opioid receptor system for reward experience and behavior in healthy humans as well as in patients in medication assisted treatment for opioid dependence. I have been part of Leknes Affective Brain lab (LABlab, PI Siri Leknes) for ten years, and am currently a postdoctoral researcher on an EU funded research project (ERC, OPIOIDREWARD) where we investigate the effects of psychological and physiological state effects on subjective effects, reward behavior and abuse liability of opioids. In addition to observational studies in different patient groups, we typically use experimental psychopharmacological designs, with and without functional neuroimaging (fMRI).

I’m a national coordinator for a work package of the NaltRec Study (Long-acting naltrexone for opioid addiction: the importance of mental, physical and societal factors for sustained abstinence and recovery; PI: Lars Tanum). In this study we assess the effects of long-acting opioid blockade with naltrexone on sensitivity to stress, reward and pain.

Courses taught

  • PSYC2230 Cognitive Neuroscience

  • PSY4320 Research methods in cognitive neuroscience Part II

  • PSY4304 Current Issues in Cognitive neuroscience

  • PSYC3102 Research project: social psychology

  • PSYC2207 Cognitive Neuroscience II


  • Laeng, Bruno; Garvija, Lara; Løseth, Guro Engvig; Eikemo, Marie; Ernst, Gernot & Leknes, Siri (2021). ‘Defrosting’ music chills with naltrexone: The role of endogenous opioids for the intensity of musical pleasure. Consciousness and Cognition.  ISSN 1053-8100.  90 . doi:
  • Sarfi, Annamaria Monika; Eikemo, Marie; Welle-Strand, Gabrielle; Muller, Ashley Elizabeth & Lehmann, Stine (2021). Mental health and use of health care services in opioid‑exposed school‑aged children compared to foster children. European Child and Adolescent Psychiatry.  ISSN 1018-8827. . doi: 10.1007/s00787-021-01728-3 Full text in Research Archive.
  • Trøstheim, Martin; Eikemo, Marie; Meir, Remy; Hansen, Ingelin; Paul, Elisabeth; Kroll, Sara Liane; Garland, Eric L. & Leknes, Siri (2020). Assessment of Anhedonia in Adults With and Without Mental Illness A Systematic Review and Meta-analysis. JAMA Network Open.  ISSN 2574-3805.  3(8) . doi: 10.1001/jamanetworkopen.2020.13233 Full text in Research Archive.
  • Eikemo, Marie; Lobmaier, Philipp Paul; Pedersen, Mads Lund; Kunøe, Nikolaj; Matziorinis, Anna Maria; Leknes, Siri & Sarfi, Annamaria Monika (2019). Intact responses to non-drug rewards in long-term opioid maintenance treatment. Neuropsychopharmacology.  ISSN 0893-133X.  44(8), s 1456- 1463 . doi: 10.1038/s41386-019-0377-9 Full text in Research Archive.
  • Garland, Eric; Trøstheim, Martin; Eikemo, Marie; Ernst, Gernot & Leknes, Siri (2019). Anhedonia in chronic pain and prescription opioid misuse. Psychological Medicine.  ISSN 0033-2917.  s 1- 12 . doi: 10.1017/S0033291719002010
  • Løseth, Guro Engvig; Eikemo, Marie & Leknes, Siri (2019). Effects of opioid receptor stimulation and blockade on touch pleasantness: a double-blind randomised trial. Social Cognitive & Affective Neuroscience.  ISSN 1749-5016.  14(4), s 411- 422 . doi: 10.1093/scan/nsz022 Full text in Research Archive.
  • van Steenbergen, Henk; Eikemo, Marie & Leknes, Siri (2019). The role of the opioid system in decision making and cognitive control: A review. Cognitive, Affective, & Behavioral Neuroscience.  ISSN 1530-7026.  19(3), s 435- 458 . doi: 10.3758/s13415-019-00710-6 Full text in Research Archive.
  • Løseth, Guro Engvig; Eikemo, Marie Helene; Isager, Peder Mortvedt; Holmgren, Jostein; Laeng, Bruno; Vindenes, Vigdis; Hjornevik, Trine & Leknes, Siri (2018). Morphine reduced perceived anger from neutral and implicit emotional expressions. Psychoneuroendocrinology.  ISSN 0306-4530.  91, s 123- 131 . doi: 10.1016/j.psyneuen.2018.02.035 Full text in Research Archive.
  • Eikemo, Marie Helene; Biele, Guido; Willoch, Frode; Thomsen, Lotte & Leknes, Siri (2017). Opioid modulation of value-based decision-making in healthy humans. Neuropsychopharmacology.  ISSN 0893-133X.  42(9), s 1833- 1840 . doi: 10.1038/npp.2017.58 Full text in Research Archive.
  • Chelnokova, Olga V; Laeng, Bruno; Løseth, Guro Engvig; Eikemo, Marie Helene; Willoch, Frode & Leknes, Siri (2016). The µ-Opioid System Promotes Visual Attention to Faces and Eyes. Social Cognitive & Affective Neuroscience.  ISSN 1749-5016.  11(12), s 1902- 1909 . doi: /10.1093/scan/nsw116
  • Eikemo, Marie Helene; Løseth, Guro Engvig; Johnstone, Tom; Gjerstad, Johannes; Willoch, Frode & Leknes, Siri (2016). Sweet taste pleasantness is modulated by morphine and naltrexone. Psychopharmacology.  ISSN 0033-3158.  233(21), s 13711- 3723 . doi: 10.1007/s00213-016-4403-x Show summary
  • Ellingsen, Dan Mikael; Wessberg, Johan; Eikemo, Marie Helene; Liljencrantz, Jaquette; Endestad, Tor; Olausson, Håkan & Leknes, Siri Graff (2013). Placebo improves pleasure and pain through opposite modulation of sensory processing. Proceedings of the National Academy of Sciences of the United States of America.  ISSN 0027-8424.  110(44), s 17993- 17998 . doi: 10.1073/pnas.1305050110

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  • Løseth, Guro; Eikemo, Marie & Leknes, Siri Graff (2019). Effects of opioid receptor stimulation and blockade on touch pleasantness: a double-blind randomised trial. Social Cognitive & Affective Neuroscience.  ISSN 1749-5016. . doi: 10.1093/scan/nsz022
  • Chelnokova, Olga V; Laeng, Bruno; Eikemo, Marie Helene; Riegels, Jeppe; Løseth, Guro; Maurud, Hedda; Willoch, Frode & Leknes, Siri (2014). Rewards of beauty: The opioid system mediates social motivation in humans. Molecular Psychiatry.  ISSN 1359-4184.  19(7), s 746- 747 . doi: 10.1038/mp.2014.1
  • Chelnokova, Olga V; Laeng, Bruno; Riegels, Jeppe; Løseth, Guro Engvig; Eikemo, Marie Helene & Leknes, Siri Graff (2013). THE HUMAN OPIOID SYSTEM MEDIATES ATTENTION TO OTHERS' EYES. Journal of Cognitive Neuroscience.  ISSN 0898-929X.  s 216- 216

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Published Jan. 7, 2021 8:15 AM - Last modified Jan. 7, 2021 9:31 AM