Kristine Beate Walhovd

• Amlien, Inge Kasbohm; Sneve, Markus Handal; Vidal-Pineiro, Didac; Walhovd, Kristine B & Fjell, Anders Martin (2019). Elaboration Benefits Source Memory Encoding Through Centrality Change. Scientific Reports.  ISSN 2045-2322.  9(1), s 1- 13 . doi: 10.1038/s41598-019-39999-1 Full text in Research Archive.
• Bjørnebekk, Astrid; Westlye, Lars Tjelta; Walhovd, Kristine B; Jørstad, Marie Lindvik; Sundset, Øyvind & Fjell, Anders Martin (2019). Cognitive Performance and Structural Brain Correlates in Long-Term Anabolic-Androgenic Steroid Exposed and Nonexposed Weightlifters. Neuropsychology.  ISSN 0894-4105.  33(4), s 547- 559 . doi: 10.1037/neu0000537
• Ferschmann, Lia; Vijayakumar, Nandita; Grydeland, Håkon; Øverbye, Knut; Sederevicius, Donatas; Due-Tønnessen, Paulina; Fjell, Anders Martin; Walhovd, Kristine B; Pfeifer, Jennifer H. & Tamnes, Christian Krog (2019). Prosocial behavior relates to the rate and timing of cortical thinning from adolescence to young adulthood. Developmental Cognitive Neuroscience.  ISSN 1878-9293.  40:100734, s 1- 8 . doi: 10.1016/j.dcn.2019.100734
• Fjell, Anders Martin; Sederevicius, Donatas; Sneve, Markus Handal; de Lange, Ann-Marie Glasø; Bråthen, Anne Cecilie Sjøli; Idland, Ane-Victoria; Watne, Leiv Otto; Wang, Yunpeng; Reinbold, Céline Sonja; Blennow, Kaj; Zetterberg, Henrik; Hong, S; Bertram, Lars & Walhovd, Kristine B (2019). Self-reported sleep problems are related to amyloid deposition in cortical regions with high HOMER1 gene expression. Cerebral Cortex.  ISSN 1047-3211.
• Fjell, Anders Martin; Sneve, Markus Handal; Sederevicius, Donatas; Sørensen, Øystein; Krogsrud, Stine Kleppe; Mowinckel, Athanasia Monika & Walhovd, Kristine B (2019). Volumetric and microstructural regional changes of the hippocampus underlying development of recall performance after extended retention intervals. Developmental Cognitive Neuroscience.  ISSN 1878-9293.  40:100723, s 1- 12 . doi: 10.1016/j.dcn.2019.100723 Full text in Research Archive.
• Fjell, Anders Martin; Sørensen, Øystein; Amlien, Inge Kasbohm; Bartrés-Faz, David; Bros, Didac Macia; Buchmann, Nikolaus; Demuth, Ilja; Drevon, Christian A.; duzel, Sandra; Ebmeier, K P; Idland, Ane-Victoria; Kietzmann, Tim C; Kievit, Rogier; Kühn, Simone; Lindenberger, Ulman; Mowinckel, Athanasia Monika; Nyberg, Lars Erik; Price, Darren; Sexton, Claire; Sole-Padulles, Cristina; Pudas, Sara; Sederevicius, Donatas; Suri, Sana; Wagner, Gerd; Watne, Leiv Otto; Westerhausen, René; Zsoldos, Eniko & Walhovd, Kristine B (2019). Self-reported sleep relates to hippocampal atrophy across the adult lifespan – results from the Lifebrain consortium. Sleep.  ISSN 0161-8105. . doi: 10.1093/sleep/zsz280 Full text in Research Archive.
• Friedman, Barbara Bodorkos; Suri, Sana; Sole-Padulles, Cristina; Düzel, Sandra; Drevon, Christian A; Baaré, William F. C.; Bartrés-Faz, David; Fjell, Anders Martin; Johansen-Berg, Heidi; Madsen, Kathrine S.; Nyberg, Lars; Penninx, Brenda W.J.H.; Sexton, Claire; Walhovd, Kristine B; Zsoldos, Enikő & Ljøsne, Isabelle Sylvie Budin (2019). Are People Ready for Personalized Brain Health? Perspectives of Research Participants in the Lifebrain Consortium. The gerontologist.  ISSN 0016-9013. . doi: 10.1093/geront/gnz155 Full text in Research Archive.
• Grydeland, Håkon; Vértes, Petra; Váša, František; Romero-Garcia, Rafael; Whitaker, Kirstie; Aaron F., Alexander-Bloch; Bjørnerud, Atle; Patel, Ameera X.; Sederevicius, Donatas; Tamnes, Christian Krog; Westlye, Lars Tjelta; White, Simon; Walhovd, Kristine B; Fjell, Anders Martin & Bullmore, Edward T. (2019). Waves of Maturation and Senescence in Microstructural MRI Markers of Human Cortical Myelination over the Lifespan. Cerebral Cortex.  ISSN 1047-3211.  29(3), s 1369- 1381 . doi: 10.1093/cercor/bhy330
• Hauger, Lisa Evju; Westlye, Lars Tjelta; Fjell, Anders Martin; Walhovd, Kristine B & Bjørnebekk, Astrid (2019). Structural brain characteristics of anabolic-androgenic steroid dependence in men. Addiction.  ISSN 0965-2140.  s 1- 11 . doi: 10.1111/add.14629
• Nygaard, Egil; Slinning, Kari; Moe, Vibeke; Fjell, Anders Martin & Walhovd, Kristine B (2019). Mental health in youth prenatally exposed to opioids and poly-drugs and raised in permanent foster/adoptive homes: A prospective longitudinal study. Early Human Development.  ISSN 0378-3782.  140 . doi: https://doi.org/10.1016/j.earlhumdev.2019.104910 Show summary

  Abstract Background Little is known about the mental health of prenatally opioid- and polydrug-exposed youth raised in foster/adoptive families. Aim To compare mental health problems among two groups of youth, one prenatally drug-exposed group with participants who were mainly placed in permanent foster or adoptive homes in early infancy and a group without known prenatal risk factors who were raised by their birth parents. Methods The sample consisted of 45 drug-exposed and 48 nonexposed youth between 17 and 22 years old from an original sample of 136 followed since birth. An extended version of the Mini International Neuropsychiatric Interview was used to assess lifetime psychiatric disorder, and participants completed the Achenbach Adult Self-Report form and Cantril's Ladder of Life Satisfaction Scale. Results A higher proportion of the youth in the drug-exposed group had lifetime experiences with major depressive episodes, alcohol abuse and attention deficit, hyperactivity disorder (OR > 3, p ≤ .030). They scored higher on the aggressive behavior scale, had more sexual partners and were younger at their sexual debut (p ≤ .030). There were no group differences in current self-reported satisfaction with life. Conclusion Youth exposed to drugs prenatally continue to represent a risk group despite early placement in permanent foster and adoptive homes. The factors contributing to this elevated risk may be multifaceted and involve adverse prenatal conditions including but not limited to drug exposure, genetics, and postnatal environmental conditions. The results highlight the need for longitudinal follow-up in the transition to adulthood as well as qualified service provision for these youth and their families.

• Smith, Steve; Duff, Eugene; Groves, Adrian; Nichols, Thomas E.; Jbabdi, Saad; Westlye, Lars Tjelta; Tamnes, Christian Krog; Engvig, Andreas; Walhovd, Kristine B; Fjell, Anders Martin; Johansen-Berg, Heidi & Douaud, Gwenaëlle (2019). Structural variability in the human brain reflects fine-grained functional architecture at the population level. Journal of Neuroscience.  ISSN 0270-6474.  39(31), s 6136- 6149 . doi: 10.1523/JNEUROSCI.2912-18.2019
• Sneve, Markus Handal; Grydeland, Håkon; Rosa, Marcello G P; Paus, Tomáš; Chaplin, Tristan; Walhovd, Kristine B & Fjell, Anders Martin (2019). High-expanding regions in primate cortical brain evolution support supramodal cognitive flexibility. Cerebral Cortex.  ISSN 1047-3211.  29(9), s 3891- 3901 . doi: 10.1093/cercor/bhy268 Full text in Research Archive.
• Vidal-Piñeiro, Didac; Sneve, Markus Handal; Nyberg, Lars; Mowinckel, Athanasia Monika; Sederevicius, Donatas; Walhovd, Kristine B & Fjell, Anders Martin (2019). Maintained Frontal Activity Underlies High Memory Function Over 8 Years in Aging. Cerebral Cortex.  ISSN 1047-3211.  29(7), s 3111- 3123 . doi: 10.1093/cercor/bhy177 Full text in Research Archive.
• Walhovd, Kristine B; Howell, Gareth R; Ritchie, Stuart J.; Staff, Roger T. & Cotman, Carl W (2019). What are the earlier life contributions to reserve and resilience?. Neurobiology of Aging.  ISSN 0197-4580.  s 1- 5 . doi: 10.1016/j.neurobiolaging.2019.04.014
• Øverbye, Knut; Walhovd, Kristine B; Paus, Tomáš; Fjell, Anders Martin; Huster, Rene & Tamnes, Christian Krog (2019). Error processing in the adolescent brain: Age-related differences in electrophysiology, behavioral adaptation, and brain morphology. Developmental Cognitive Neuroscience.  ISSN 1878-9293.  38 . doi: 10.1016/j.dcn.2019.100665
• Amlien, Inge Kasbohm; Sneve, Markus Handal; Vidal-Piñeiro, Didac; Walhovd, Kristine B & Fjell, Anders Martin (2018). The lifespan trajectory of the encoding-retrieval flip: A multimodal examination of medial parietal cortex contributions to episodic memory. Journal of Neuroscience.  ISSN 0270-6474.  38(40), s 8666- 8679 . doi: 10.1523/JNEUROSCI.1702-17.2018
• Bråthen, Anne Cecilie Sjøli; de Lange, Ann-Marie Glasø; Rohani, Darius; Sneve, Markus Handal; Fjell, Anders Martin & Walhovd, Kristine B (2018). Multimodal cortical and hippocampal prediction of episodic‐memory plasticity in young and older adults. Human Brain Mapping.  ISSN 1065-9471.  39(11), s 4480- 4492 . doi: 10.1002/hbm.24287
• de Lange, Ann-Marie Glasø; Bråthen, Anne Cecilie Sjøli; Rohani, Darius; Fjell, Anders Martin & Walhovd, Kristine B (2018). The Temporal Dynamics of Brain Plasticity in Aging. Cerebral Cortex.  ISSN 1047-3211. . doi: 10.1093/cercor/bhy003
• Ferschmann, Lia; Fjell, Anders Martin; Vollrath, Margarete E.; Grydeland, Håkon; Walhovd, Kristine B & Tamnes, Christian Krog (2018). Personality Traits Are Associated With Cortical Development Across Adolescence: A Longitudinal Structural MRI Study. Child Development.  ISSN 0009-3920.  89(3), s 811- 822 . doi: 10.1111/cdev.13016 Full text in Research Archive.
• Fjell, Anders Martin; Chen, Chi-Hua Chen; Sederevicius, Donatas; Sneve, Markus Handal; Grydeland, Håkon; Krogsrud, Stine Kleppe; Amlien, Inge Kasbohm; Ferschmann, Lia; Ness, Hedda; Folvik, Line; Beck, Dani; Mowinckel, Athanasia Monika; Tamnes, Christian Krog; Westerhausen, René; Håberg, Asta; Dale, Anders M & Walhovd, Kristine B (2018). Continuity and discontinuity in human cortical development and change from embryonic stages to old age. Cerebral Cortex.  ISSN 1047-3211.  s 1- 12 . doi: 10.1093/cercor/bhy266 Full text in Research Archive.
• Haabrekke, Kristin Johanne Økern; Siqveland, Torill Sundet; Nygaard, Egil; Bjørnebekk, Astrid; Slinning, Kari; Wentzel-Larsen, Tore; Walhovd, Kristine B; Smith, Lars & Moe, Vibeke (2018). Cognitive and socioemotional functioning at 4½ years in children born to mothers who have received treatment for substance-abuse problems while pregnant. Infant Mental Health Journal.  ISSN 0163-9641.  39(5), s 581- 594 . doi: 10.1002/imhj.21733
• Krogsrud, Stine Kleppe; Fjell, Anders Martin; Tamnes, Christian Krog; Grydeland, Håkon; Due-Tønnessen, Paulina; Bjørnerud, Atle; Sampaio-Baptista, Cassandra; Andersson, Jesper; Johansen-Berg, Heidi & Walhovd, Kristine B (2018). Development of white matter microstructure in relation to verbal and visuospatial working memory - A longitudinal study. PLOS ONE.  ISSN 1932-6203.  13:e0195540(4), s 1- 22 . doi: 10.1371/journal.pone.0195540
• Langnes, Espen; Vidal-Piñeiro, Didac; Sneve, Markus Handal; Amlien, Inge Kasbohm; Walhovd, Kristine B & Fjell, Anders Martin (2018). Development and decline of the hippocampal long-axis specialization and differentiation during encoding and retrieval of episodic memories. Cerebral Cortex.  ISSN 1047-3211.  s 1- 17 . doi: 10.1093/cercor/bhy209 Full text in Research Archive.
• Nyberg, Claudia Kim; Nordvik, Jan Egil; Becker, Frank; Rohani, Darius; Sederevicius, Donatas; Fjell, Anders Martin & Walhovd, Kristine B (2018). A longitudinal study of computerized cognitive training in stroke patients - effects on cognitive function and white matter. Topics in Stroke Rehabilitation.  ISSN 1074-9357.  25(4), s 241- 247 . doi: 10.1080/10749357.2018.1443570
• Nygaard, Egil; Slinning, Kari; Moe, Vibeke; Due-Tønnessen, Paulina; Fjell, Anders Martin & Walhovd, Kristine B (2018). Neuroanatomical characteristics of youths with prenatal opioid and poly-drug exposure. Neurotoxicology and Teratology.  ISSN 0892-0362.  68, s 13- 26 . doi: 10.1016/j.ntt.2018.04.004 Full text in Research Archive.
• Skumlien, Martine; Sederevicius, Donatas; Fjell, Anders Martin; Walhovd, Kristine B & Westerhausen, Rene (2018). Parallel but independent reduction of emotional awareness and corpus callosum connectivity in older age. PLOS ONE.  ISSN 1932-6203.  13(12), s 1- 18 . doi: 10.1371/journal.pone.0209915 Full text in Research Archive.
• Tamnes, Christian Krog; Øverbye, Knut; Ferschmann, Lia; Fjell, Anders Martin; Walhovd, Kristine B; Blakemore, Sarah-Jayne & Dumontheil, Iroise (2018). Social perspective taking is associated with self-reported prosocial behavior and regional cortical thickness across adolescence. Developmental Psychology.  ISSN 0012-1649.  54(9), s 1745- 1757 . doi: 10.1037/dev0000541
• Walhovd, Kristine B; Fjell, Anders Martin; Westerhausen, René; Nyberg, L; Ebmeier, K P; Lindenberger, U; Bartres-Faz, D; Baare, W F C; Siebner, H R; Henson, R; Drevon, C A; Knudsen, Gun Peggy S.; Ljøsne, Isabelle Budin; Penninx, B W J H; Ghisletta, P; Røgeberg, Ole; Tyler, L & Bertram, L (2018). Healthy minds 0-100 years: Optimising the use of European brain imaging cohorts ("Lifebrain"). European psychiatry.  ISSN 0924-9338.  50, s 47- 56 . doi: 10.1016/j.eurpsy.2017.12.006 Full text in Research Archive.
• Øverbye, Knut; Huster, Rene; Walhovd, Kristine B; Fjell, Anders Martin & Tamnes, Christian Krog (2018). Development of the P300 from childhood to adulthood: a multimodal EEG and MRI study. Brain Structure and Function.  ISSN 1863-2653.  223, s 4337- 4349 . doi: 10.1007/s00429-018-1755-5
• de Lange, Ann-Marie Glasø; Bråthen, Anne Cecilie Sjøli; Rohani, Darius; Grydeland, Håkon; Fjell, Anders Martin & Walhovd, Kristine B (2017). The Effects of Memory Training on Behavioral and Microstructural Plasticity in Young and Older Adults. Human Brain Mapping.  ISSN 1065-9471.  38(11), s 5666- 5680 . doi: 10.1002/hbm.23756 Full text in Research Archive.
• Fjell, Anders Martin; Idland, Ane-Victoria; Sala Llonch, Roser; Watne, Leiv Otto; Borza, Tom; Brækhus, Anne; Lona, Tarjei; Zetterberg, Henrik; Blennow, Kaj; Wyller, Torgeir Bruun & Walhovd, Kristine B (2017). Neuroinflammation and tau interact with amyloid in predicting sleep problems in aging independently of atrophy. Cerebral Cortex.  ISSN 1047-3211.  28(8), s 2775- 2785 . doi: 10.1093/cercor/bhx157
• Fjell, Anders Martin; Sneve, Markus Handal; Grydeland, Håkon; Storsve, Andreas Berg; Amlien, Inge Kasbohm; Yendiki, Anastasia & Walhovd, Kristine B (2017). Relationship between structural and functional connectivity change across the lifespan – a longitudinal investigation. Human Brain Mapping.  ISSN 1065-9471.  38(1), s 561- 573 . doi: 10.1002/hbm.23403 Full text in Research Archive.
• Idland, Ane-Victoria; Roser, Sala-Llonch; Borza, Tom; Watne, Leiv Otto; Wyller, Torgeir Bruun; Brækhus, Anne; Zetterberg, Henrik; Blennow, Kaj; Walhovd, Kristine B & Fjell, Anders Martin (2017). CSF neurofilament light levels predict hippocampal atrophy in cognitively healthy older adults. Neurobiology of Aging.  ISSN 0197-4580.  49, s 138- 144 . doi: 10.1016/j.neurobiolaging.2016.09.012 Full text in Research Archive.
• Nygaard, Egil; Slinning, Kari; Moe, Vibeke & Walhovd, Kristine B (2017). Cognitive function of youths born to mothers with opioid and poly-substance abuse problems during pregnancy. Child Neuropsychology: A Journal of Normal and Abnormal Development in Childhood and Adolescence.  ISSN 0929-7049.  23(2), s 159- 187 . doi: 10.1080/09297049.2015.1092509 Full text in Research Archive.
• Sala Llonch, Roser; Idland, Ane-Victoria; Borza, Tom; Watne, Leiv Otto; Wyller, Torgeir Bruun; Brækhus, Anne; Zetterberg, Henrik; Blennow, Kaj; Walhovd, Kristine B & Fjell, Anders Martin (2017). Inflammation, Amyloid, and Atrophy in The Aging Brain: Relationships with Longitudinal Changes in Cognition. Journal of Alzheimer's Disease.  ISSN 1387-2877.  58(3), s 829- 840 . doi: 10.3233/JAD-161146 Show summary

  Amyloid deposition occurs in aging, even in individuals free from cognitive symptoms, and is often interpreted as preclinical Alzheimer’s disease (AD) pathophysiology. YKL-40 is a marker of neuroinflammation, being increased in AD, and hypothesized to interact with amyloid-β (Aβ) in causing cognitive decline early in the cascade of AD pathophysiology. Whether and how Aβ and YKL-40 affect brain and cognitive changes in cognitively healthy older adults is still unknown. We studied 89 participants (mean age: 73.1 years) with cerebrospinal fluid samples at baseline, and both MRI and cognitive assessments from two time-points separated by two years. We tested how baseline levels of Aβ42 and YKL-40 correlated with changes in cortical thickness and cognition. Thickness change correlated with Aβ42 only in Aβ42+ participants (<600 pg/mL, n = 27) in the left motor and premotor cortices. Aβ42 was unrelated to cognitive change. Increased YKL-40 was associated with less preservation of scores on the animal naming test in the total sample (r = –0.28, p = 0.012) and less preservation of a score reflecting global cognitive function for Aβ42+ participants (r = –0.58, p = 0.004). Our results suggest a role for inflammation in brain atrophy and cognitive changes in cognitively normal older adults, which partly depended on Aβ accumulation.

• Sneve, Markus Handal; Grydeland, Håkon; Amlien, Inge Kasbohm; Langnes, Espen; Walhovd, Kristine B & Fjell, Anders Martin (2017). Decoupling of large-scale brain networks supports the consolidation of durable episodic memories. NeuroImage.  ISSN 1053-8119.  153, s 336- 345 . doi: 10.1016/j.neuroimage.2016.05.048 Full text in Research Archive.
• Vidal-Piñeiro, Didac; Sneve, Markus Handal; Storsve, Andreas Berg; Roe, James Michael; Walhovd, Kristine B & Fjell, Anders Martin (2017). Neural correlates of durable memories across the adult lifespan: brain activity at encoding and retrieval. Neurobiology of Aging.  ISSN 0197-4580.  60, s 20- 33 . doi: 10.1016/j.neurobiolaging.2017.08.017 Full text in Research Archive.
• Westerhausen, Rene; Friesen, Charline-Marie; Rohani, Darius; Krogsrud, Stine Kleppe; Tamnes, Christian Krog; Skranes, Jon Sverre; Håberg, Asta; Fjell, Anders Martin & Walhovd, Kristine B (2017). The corpus callosum as anatomical marker of intelligence? A critical examination in a large-scale developmental study. Brain Structure and Function.  ISSN 1863-2653.  223, s 285- 296 . doi: 10.1007/s00429-017-1493-0
• Almaas, Astrid; Tamnes, Christian Krog; Nakstad, Britt; Henriksen, Christine; Grydeland, Håkon; Walhovd, Kristine B; Fjell, Anders Martin; Iversen, Per Ole & Drevon, Christian A (2016). Diffusion tensor imaging and behavior in premature infants at 8 years of age, a randomized controlled trial with long-chain polyunsaturated fatty acids. Early Human Development.  ISSN 0378-3782.  95, s 41- 46 . doi: 10.1016/j.earlhumdev.2016.01.021
• Amlien, Inge; Fjell, Anders Martin; Tamnes, Christian Krog; Grydeland, Håkon; Krogsrud, Stine Kleppe; Chaplin, Tristan A.; Rosa, Marcello G.P. & Walhovd, Kristine B (2016). Organizing Principles of Human Cortical Development - Thickness and Area from 4 to 30 Years: Insights from Comparative Primate Neuroanatomy. Cerebral Cortex.  ISSN 1047-3211.  26(1), s 257- 267 . doi: 10.1093/cercor/bhu214
• Chepkoech, Joy-Loi; Walhovd, Kristine B; Grydeland, Håkon & Fjell, Anders Martin (2016). Effects of change in FreeSurfer version on classification accuracy of patients with Alzheimer's disease and mild cognitive impairment. Human Brain Mapping.  ISSN 1065-9471.  37(5), s 1831- 1841 . doi: 10.1002/hbm.23139
• de Lange, Ann-Marie Glasø; Bråthen, Anne Cecilie Sjøli; Grydeland, Håkon; Sexton, Claire; Johansen-Berg, Heidi; Andersson, Jesper L.R.; Rohani, Darius; Nyberg, Lars; Fjell, Anders Martin & Walhovd, Kristine B (2016). White-matter integrity as a marker for cognitive plasticity in aging. Neurobiology of Aging.  ISSN 0197-4580.  47, s 74- 82 . doi: 10.1016/j.neurobiolaging.2016.07.007
• Fjell, Anders Martin; Sneve, Markus Handal; Grydeland, Håkon; Storsve, Andreas Berg & Walhovd, Kristine B (2016). The Disconnected Brain and Executive Function Decline in Aging. Cerebral Cortex.  ISSN 1047-3211. . doi: 10.1093/cercor/bhw082 Full text in Research Archive.
• Fjell, Anders Martin; Sneve, Markus Handal; Storsve, Andreas Berg; Grydeland, Håkon; Yendiki, Anastasia & Walhovd, Kristine B (2016). Brain Events Underlying Episodic Memory Changes in Aging: A Longitudinal Investigation of Structural and Functional Connectivity. Cerebral Cortex.  ISSN 1047-3211.  26(3), s 1272- 1286 . doi: 10.1093/cercor/bhv102 Full text in Research Archive.
• Grydeland, Håkon; Westlye, Lars Tjelta; Walhovd, Kristine B & Fjell, Anders Martin (2016). Intracortical Posterior Cingulate Myelin Content Relates to Error Processing – Results From T1- and T2-weighted MRI Myelin Mapping and Electrophysiology in Healthy Adults. Cerebral Cortex.  ISSN 1047-3211.  26(6), s 2402- 2410 . doi: 10.1093/cercor/bhv065 Full text in Research Archive.
• Krogsrud, Stine Kleppe; Fjell, Anders Martin; Tamnes, Christian Krog; Grydeland, Håkon; Ferschmann, Lia; Due-Tønnessen, Paulina; Bjørnerud, Atle; Sampaio-Baptista, Cassandra; Andersson, Jesper; Johansen-Berg, Heidi & Walhovd, Kristine B (2016). Changes in white matter microstructure in the developing brain - A longitudinal diffusion tensor imaging study of children from 4 to 11years of age. NeuroImage.  ISSN 1053-8119.  124, s 473- 486 . doi: 10.1016/j.neuroimage.2015.09.017
• Nygaard, Egil; Slinning, Kari; Moe, Vibeke & Walhovd, Kristine B (2016). Behavior and attention problems in eight- year-old children with prenatal opiate and poly-substance exposure: A longitudinal study. PLOS ONE.  ISSN 1932-6203.  11(6) . doi: 10.1371/journal.pone.0158054 Full text in Research Archive.
• Piñeiro, Didac Vidal; Walhovd, Kristine B; Storsve, Andreas Berg; Grydeland, Håkon; Rohani, Darius Adam & Fjell, Anders Martin (2016). Accelerated longitudinal gray/white matter contrast decline in aging in lightly myelinated cortical regions. Human Brain Mapping.  ISSN 1065-9471.  37(10), s 3669- 3684 . doi: 10.1002/hbm.23267 Full text in Research Archive.
• Storsve, Andreas Berg; Fjell, Anders Martin; Yendiki, Anastasia & Walhovd, Kristine B (2016). Longitudinal changes in white matter tract integrity across the adult lifespan and its relation to cortical thinning. PLOS ONE.  ISSN 1932-6203.  11(6) . doi: 10.1371/journal.pone.0156770 Full text in Research Archive.
• Walhovd, Kristine B; Fjell, Anders Martin; Giedd, J; Dale, AM & Brown, Timothy T. (2016). Through thick and thin: A need to reconcile contradictory results on trajectories in human cortical development. Cerebral Cortex.  ISSN 1047-3211. . doi: 10.1093/cercor/bhv301 Full text in Research Archive.
• Walhovd, Kristine B; Krogsrud, Stine Kleppe; Amlien, Inge Kasbohm; Bartsch, Hauke; Bjørnerud, Atle; Due-Tønnessen, Paulina; Grydeland, Håkon; Hagler, D.; Håberg, Asta; Kremen, William S.; Ferschmann, Lia; Nyberg, Lars; Panizzon, Matthew S; Rohani, Darius; Skranes, Jon Sverre; Storsve, Andreas Berg; Sølsnes, Anne Elisabeth; Tamnes, Christian Krog; Thompson, Wesley K.; Reuter, Chase; Dale, Anders & Fjell, Anders Martin (2016). Neurodevelopmental origins of lifespan changes in brain and cognition. Proceedings of the National Academy of Sciences of the United States of America.  ISSN 0027-8424.  113(33), s 9357- 9362 . doi: 10.1073/pnas.1524259113 Full text in Research Archive.
• Walhovd, Kristine B; Westerhausen, Rene; de Lange, Ann-Marie Glasø; Bråthen, Anne Cecilie Sjøli; Grydeland, Håkon; Engvig, Andreas & Fjell, Anders Martin (2016). Premises of plasticity - And the loneliness of the medial temporal lobe. NeuroImage.  ISSN 1053-8119.  131, s 48- 54 . doi: 10.1016/j.neuroimage.2015.10.060 Full text in Research Archive.
• Westerhausen, Rene; Fjell, Anders Martin; Krogsrud, Stine Kleppe; Rohani, Darius Adam; Skranes, Jon Sverre; Håberg, Asta & Walhovd, Kristine B (2016). Selective increase in posterior corpus callosum thickness between the age of 4 and 11 years. NeuroImage.  ISSN 1053-8119.  139, s 17- 25 . doi: 10.1016/j.neuroimage.2016.06.008
• Almaas, Astrid; Tamnes, Christian Krog; Nakstad, Britt; Henriksen, Christine; Walhovd, Kristine B; Fjell, Anders Martin; Due-Tønnessen, Paulina; Drevon, Christian A & Iversen, Per Ole (2015). Long-chain polyunsaturated fatty acids and cognition in VLBW infants at 8 years: An RCT. Pediatrics.  ISSN 0031-4005.  135(6), s 972- 980 . doi: 10.1542/peds.2014-4094
• Fjell, Anders Martin; Amlien, Inge; Sneve, Markus Handal; Grydeland, Håkon; Tamnes, Christian Krog; Chaplin, Tristan; Rosa, Marcello & Walhovd, Kristine B (2015). The roots of Alzheimer's disease: Are high-expanding cortical areas preferentially targeted?. Cerebral Cortex.  ISSN 1047-3211.  25(9), s 2556- 2565 . doi: 10.1093/cercor/bhu055 Full text in Research Archive.
• Fjell, Anders Martin; Grydeland, Håkon; Krogsrud, Stine Kleppe; Amlien, Inge Kasbohm; Rohani, Darius Adam; Ferschmann, Lia; Storsve, Andreas Berg; Tamnes, Christian Krog; Sala Llonch, Roser; Due-Tønnessen, Paulina; Bjørnerud, Atle; Sølsnes, Anne Elisabeth; Håberg, Asta; Skranes, Jon Sverre; Bartsch, Hauke; Chen, Chi-Hua; Thompson, Wesley K.; Panizzon, Matthew S.; Kremen, William S.; Dale, Anders M. & Walhovd, Kristine B (2015). Development and aging of cortical thickness correspond to genetic organization patterns. Proceedings of the National Academy of Sciences of the United States of America.  ISSN 0027-8424.  112(50), s 15462- 15467 . doi: 10.1073/pnas.1508831112 Full text in Research Archive. Show summary

  There is a growing realization that early life influences have lasting impact on brain function and structure. Recent research has demon- strated that genetic relationships in adults can be used to parcellate the cortex into regions of maximal shared genetic influence, and a major hypothesis is that genetically progr ammed neurodevel opmental events cause a lasting impact on the organization of the cerebral cortex observable decades later. Here we tested how developmental and lifespan changes in cortical thickness fit the underlying genetic organi- zational principles of co rtical thickness in a longitudinal sample of 974 participants between 4.1 and 88.5 y of age with a total of 1,633 scans, including 773 scans from children below 12 y. Genetic clustering of cortical thickness was based on an independent dataset of 406 adult twins. Developmental and adult age- related changes in cortical thick- ness followed closely the genetic organization of the cerebral cortex, with change rates varying as a functi on of genetic similarity between regions. Cortical regions with overlapping genetic architecture showed correlated development al and adult age change trajectories and vice versa for regions with low genetic overlap. Thus, effects of genes on regional variations in cortical thickness in middle age can be traced to regional differences in neurodevelopmental change rates and extrap- olated to further adult aging-related cortical thinning. This finding suggests that genetic factors contribute to cortical changes through life and calls for a lifespan perspective i n research aimed at identifying the genetic and environmental determinants of cortical development and aging.

• Fjell, Anders Martin; Sneve, Markus Handal; Grydeland, Håkon; Storsve, Andreas Berg; de Lange, Ann-Marie Glasø; Amlien, Inge Kasbohm; Røgeberg, Ole & Walhovd, Kristine B (2015). Functional connectivity change across multiple cortical networks relates to episodic memory changes in aging. Neurobiology of Aging.  ISSN 0197-4580.  36(12), s 3255- 3268 . doi: 10.1016/j.neurobiolaging.2015.08.020 Full text in Research Archive.
• Fjell, Anders Martin; Westlye, Lars Tjelta; Amlien, Inge; Tamnes, Christian Krog; Grydeland, Håkon; Engvig, Andreas; Espeseth, Thomas; Reinvang, Ivar; Lundervold, Astri; Lundervold, Arvid & Walhovd, Kristine B (2015). High-expanding cortical regions in human development and evolution are related to higher intellectual abilities. Cerebral Cortex.  ISSN 1047-3211.  25, s 26- 34 . doi: 10.1093/cercor/bht201 Full text in Research Archive.
• Jack, Clifford R.; Barnes, Josephine; Bernstein, Matt A.; Borowski, Bret J.; Brewer, James; Clegg, Shona; Dale, Anders M.; Carmichael, Owen; Ching, Christopher; DeCarli, Charles; Desikan, Rahul S.; Fennema-Notestine, Christine; Fjell, Anders Martin; Fletcher, Evan; Fox, Nick C.; Gunter, Jeff; Gutman, Boris A.; Holland, Dominic; Hua, Xue; Insel, Philip; Kantarci, Kejal; Killiany, Ron J.; Krueger, Gunnar; Leung, Kelvin K.; Mackin, Scott; Maillard, Pauline; Malone, Ian B.; Mattsson, Niklas; McEvoy, Linda; Modat, Marc; Mueller, Susanne; Nosheny, Rachel; Ourselin, Sebastien; Schuff, Norbert; Senjem, Matthew L.; Simonson, Alix; Thompson, Paul M.; Rettmann, Dan; Vemuri, Prashanthi; Walhovd, Kristine B; Zhao, Yansong; Zuk, Samantha & Weiner, Michael (2015). Magnetic resonance imaging in Alzheimer's Disease Neuroimaging Initiative 2. Alzheimer's & Dementia.  ISSN 1552-5260.  11(7), s 740- 756 . doi: 10.1016/j.jalz.2015.05.002
• Kanellopoulos, Adriani; Andersson, Stein; Zeller, Bernward; Tamnes, Christian Krog; Fjell, Anders Martin; Walhovd, Kristine B; Westlye, Lars Tjelta; Fosså, Sophie Dorothea & Ruud, Ellen (2015). Neurocognitive Outcome in Very Long-Term Survivors of Childhood Acute Lymphoblastic Leukemia After Treatment with Chemotherapy Only. Pediatric Blood & Cancer.  ISSN 1545-5009.  63(1), s 133- 138 . doi: 10.1002/pbc.25690
• Nygaard, Egil; Moe, Vibeke; Slinning, Kari & Walhovd, Kristine B (2015). Longitudinal cognitive development of children born to mothers with opioid and polysubstance use. Pediatric Research.  ISSN 0031-3998.  78(3), s 330- 335 . doi: 10.1038/pr.2015.95
• Nygaard, Gro Owren; Celius, Elisabeth Gulowsen; de Rodez Benavent, Sigrid Aune; Sowa, Piotr; Gustavsen, Marte Wendel; Fjell, Anders Martin; Landrø, Nils Inge; Walhovd, Kristine B & Harbo, Hanne Flinstad (2015). A longitudinal study of disability, cognition and gray matter atrophy in early multiple sclerosis patients according to evidence of disease activity. PLOS ONE.  ISSN 1932-6203.  10(8) . doi: 10.1371/journal.pone.0135974 Full text in Research Archive.
• Nygaard, Gro Owren; Walhovd, Kristine B; Sowa, Piotr; Chepkoech, Joy-Loi; Bjørnerud, Atle; Due-Tønnessen, Paulina; Landrø, Nils Inge; Damangir, Soheil; Spulber, Gabriela; Storsve, Andreas Berg; Kristiansen Beyer, Mona; Fjell, Anders Martin; Celius, Elisabeth Gulowsen & Harbo, Hanne Flinstad (2015). Cortical thickness and surface area relate to specific symptoms in early relapsing−remitting multiple sclerosis. Multiple Sclerosis.  ISSN 1352-4585.  21(4), s 402- 414 . doi: 10.1177/1352458514543811
• Sneve, Markus Handal; Grydeland, Håkon; Nyberg, Lars; Bowles, Ben; Amlien, Inge Kasbohm; Langnes, Espen; Walhovd, Kristine B & Fjell, Anders Martin (2015). Mechanisms underlying encoding of short-lived versus durable episodic memories. Journal of Neuroscience.  ISSN 0270-6474.  35(13), s 5202- 5212 . doi: 10.1523/JNEUROSCI.4434-14.2015 Full text in Research Archive.
• Tamnes, Christian Krog; Zeller, Bernward; Amlien, Inge; Kanellopoulos, Adriani; Andersson, Stein; Due-Tønnessen, Paulina; Ruud, Ellen; Walhovd, Kristine B & Fjell, Anders Martin (2015). Cortical surface area and thickness in adult survivors of pediatric acute lymphoblastic leukemia. Pediatric Blood & Cancer.  ISSN 1545-5009.  62(6), s 1027- 1034 . doi: 10.1002/pbc.25386
• Walhovd, Kristine B; Bjørnebekk, Astrid; Haabrekke, Kristin Johanne; Siqveland, Torill; Slinning, Kari; Nygaard, Egil; Fjell, Anders Martin; Due-Tønnessen, Paulina; Bjørnerud, Atle & Moe, Vibeke (2015). Child Neuroanatomical, Neurocognitive, and Visual Acuity Outcomes With Maternal Opioid and Polysubstance Detoxification. Pediatric Neurology.  ISSN 0887-8994.  52(3), s 326- 332.e3 . doi: 10.1016/j.pediatrneurol.2014.11.008
• Walhovd, Kristine B; Tamnes, Christian Krog; Bjørnerud, Atle; Due-Tønnessen, Paulina; Holland, Dominic; Dale, Anders M. & Fjell, Anders Martin (2015). Maturation of Cortico-Subcortical Structural Networks - Segregation and Overlap of Medial Temporal and Fronto-Striatal Systems in Development. Cerebral Cortex.  ISSN 1047-3211.  25(7), s 1835- 1841 . doi: 10.1093/cercor/bht424
• Bjørnebekk, Astrid; Siqveland, Torill; Haabrekke, Kristin Johanne; Moe, Vibeke; Slinning, Kari; Fjell, Anders Martin & Walhovd, Kristine B (2014). Development of children born to mothers with mental health problems: subcortical volumes and cognitive performance at 4½ years. European Child and Adolescent Psychiatry.  ISSN 1018-8827.  24(1), s 115- 118 . doi: 10.1007/s00787-014-0625-9
• Douaud, Gwenaëlle; Groves, Adrian; Tamnes, Christian Krog; Westlye, Lars Tjelta; Duff, Eugene; Engvig, Andreas; Walhovd, Kristine B; James, Anthony; Gass, Achim; Monsch, Andreas U.; Matthews, Paul M.; Fjell, Anders Martin; Smith, Stephen & Johansen-Berg, Heidi (2014). A common brain network links development, aging, and vulnerability to disease. Proceedings of the National Academy of Sciences of the United States of America.  ISSN 0027-8424.  111(49), s 17648- 17653 . doi: 10.1073/pnas.1410378111
• Engvig, Andreas; Fjell, Anders Martin; Westlye, Lars Tjelta; Skaane, Nina Voss; Dale, Anders M.; Holland, Dominic; Due-Tønnessen, Paulina; Sundset, Øyvind & Walhovd, Kristine B (2014). Effects of Cognitive Training on Gray Matter Volumes in Memory Clinic Patients with Subjective Memory Impairment. Journal of Alzheimer's Disease.  ISSN 1387-2877. . doi: 10.3233/JAD-131889 Full text in Research Archive.
• Fjell, Anders Martin; McEvoy, Linda; Holland, Dominic; Dale, Anders & Walhovd, Kristine B (2014). What is normal in normal aging? Effects of aging, amyloid and Alzheimer's disease on the cerebral cortex and the hippocampus. Progress in Neurobiology.  ISSN 0301-0082.  117, s 20- 40 . doi: 10.1016/j.pneurobio.2014.02.004 Full text in Research Archive.
• Fjell, Anders Martin; Westlye, Lars Tjelta; Grydeland, Håkon; Amlien, Inge; Espeseth, Thomas; Reinvang, Ivar; Raz, Naftali; Dale, Anders & Walhovd, Kristine B (2014). Accelerating cortical thinning: Unique to dementia or universal in aging?. Cerebral Cortex.  ISSN 1047-3211.  24(4), s 919- 934 . doi: 10.1093/cercor/bhs379
• Haabrekke, Kristin Johanne; Siqveland, Torill; Smith, Lars; Wentzel-Larsen, Tore; Walhovd, Kristine B & Moe, Vibeke (2014). Mother–Child Interaction and Early Language Skills in Children Born to Mothers with Substance Abuse and Psychiatric Problems. Child Psychiatry and Human Development.  ISSN 0009-398X. . doi: 10.1007/s10578-014-0512-0
• Haabrekke, Kristin Johanne; Slinning, Kari; Walhovd, Kristine B; Wentzel-Larsen, Tore & Moe, Vibeke (2014). The perinatal outcome of children born to women with substance dependence detoxified in residential treatment during pregnancy. Journal of Addictive Diseases.  ISSN 1055-0887.  33(2), s 114- 123 . doi: 10.1080/10550887.2014.909698
• Krogsrud, Stine Kleppe; Tamnes, Christian Krog; Fjell, Anders Martin; Amlien, Inge; Grydeland, Håkon; Sulutvedt, Unni; Due-Tønnessen, Paulina; Bjørnerud, Atle; Sølsnes, Anne Elisabeth; Håberg, Asta; Skranes, Jon Sverre & Walhovd, Kristine B (2014). Development of hippocampal subfield volumes from 4 to 22 years. Human Brain Mapping.  ISSN 1065-9471.  35(11), s 5646- 5657 . doi: 10.1002/hbm.22576 Full text in Research Archive.
• Nordvik, Jan Egil; Walle, Kjersti Mæhlum; Nyberg, Claudia; Fjell, Anders Martin; Walhovd, Kristine B; Westlye, Lars Tjelta & Tornås, Sveinung (2014). Bridging the gap between clinical neuroscience and cognitive rehabilitation: The role of cognitive training, models of neuroplasticity and advanced neuroimaging in future brain injury rehabilitation. NeuroRehabilitation (Reading, MA).  ISSN 1053-8135.  34(1), s 81- 85 . doi: 10.3233/NRE-131017
• Sexton, Claire E; Storsve, Andreas Berg; Walhovd, Kristine B; Johansen-Berg, Heidi & Fjell, Anders Martin (2014). Poor Sleep Quality is Associated With Increased Cortical Atrophy in Community-Dwelling Adults. Neurology.  ISSN 0028-3878.  83(11), s 967- 973 . doi: 10.1212/WNL.0000000000000774
• Sexton, Claire E; Walhovd, Kristine B; Storsve, Andreas Berg; Tamnes, Christian Krog; Westlye, Lars Tjelta; Johansen-Berg, Heidi & Fjell, Anders Martin (2014). Accelerated changes in white matter microstructure during aging: A longitudinal diffusion tensor imaging study. Journal of Neuroscience.  ISSN 0270-6474.  34(46), s 15425- 15436 . doi: 10.1523/JNEUROSCI.0203-14.2014
• Storsve, Andreas Berg; Fjell, Anders Martin; Tamnes, Christian Krog; Westlye, Lars Tjelta; Øverbye, Knut; Aasland, Hilde Wiede & Walhovd, Kristine B (2014). Differential longitudinal changes in cortical thickness, surface area and volume across the adult lifespan: Regions of accelerating and decelerating change. Journal of Neuroscience.  ISSN 0270-6474.  34(25), s 8488- 8498 . doi: 10.1523/JNEUROSCI.0391-14.2014 Full text in Research Archive.
• Strømmen, Kenneth; Blakstad, Elin Wahl; Moltu, Sissel; Almaas, Astrid; Westerberg, Ane Cecilie; Amlien, Inge; Rønnestad, Arild Erlend; Nakstad, Britt; Drevon, Christian A; Bjørnerud, Atle; Courivaud, Fredric A A; Hol, Per Kristian; Veierød, Marit Bragelien; Fjell, Anders Martin; Walhovd, Kristine B & Iversen, Per Ole (2014). Enhanced Nutrient Supply to Very Low Birth Weight Infants is Associated with Improved White Matter Maturation and Head Growth. Neonatology.  ISSN 1661-7800.  107(1), s 68- 75 . doi: 10.1159/000368181
• Tamnes, Christian Krog; Walhovd, Kristine B; Engvig, Andreas; Grydeland, Håkon; Krogsrud, Stine Kleppe; Østby, Ylva; Holland, Dominic; Dale, Anders & Fjell, Anders Martin (2014). Regional hippocampal volumes and development predict learning and memory. Developmental Neuroscience.  ISSN 0378-5866.  36(3-4), s 161- 174 . doi: 10.1159/000362445 Full text in Research Archive.
• Walhovd, Kristine B; Fjell, Anders Martin & Espeseth, Thomas (2014). Cognitive decline and brain pathology in aging - need for a dimensional, lifespan and systems vulnerability view. Scandinavian Journal of Psychology.  ISSN 0036-5564.  55(3), s 244- 254 . doi: 10.1111/sjop.12120 Full text in Research Archive.
• Walhovd, Kristine B; Johansen-Berg, Heidi & Karadottir, Ragnhildur (2014). Unraveling the secrets of white matter - Bridging the gap between cellular, animal and human imaging studies. Neuroscience.  ISSN 0306-4522.  276, s 2- 13 . doi: 10.1016/j.neuroscience.2014.06.058
• Walhovd, Kristine B; Storsve, Andreas Berg; Westlye, Lars Tjelta; Drevon, Christian A & Fjell, Anders Martin (2014). Blood markers of fatty acids and vitamin D, cardiovascular measures, body mass index, and physical activity relate to longitudinal cortical thinning in normal aging. Neurobiology of Aging.  ISSN 0197-4580.  35(5), s 1055- 1064 . doi: 10.1016/j.neurobiolaging.2013.11.011
• Walhovd, Kristine B; Tamnes, Christian Krog & Fjell, Anders Martin (2014). Brain structural maturation and the foundations of cognitive behavioral development. Current Opinion in Neurology.  ISSN 1350-7540.  27(2), s 176- 184 . doi: 10.1097/WCO.0000000000000074 Full text in Research Archive.

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• Nygaard, Egil; Slinning, Kari; Moe, Vibeke & Walhovd, Kristine B (2017). Hvordan går det med ungdom som ble født av mødre med blandingsmisbruk under svangerskapet?.
• Nygaard, Egil; Slinning, Kari; Moe, Vibeke & Walhovd, Kristine B (2017). Hvordan går det med ungdom som ble født av mødre med blandingsmisbruk under svangerskapet?.
• Nygaard, Egil; Slinning, Kari; Moe, Vibeke & Walhovd, Kristine B (2017). Neurocognitive differences and mental health after prenatal opiate and polysubstance exposure.
• Nygaard, Egil; Slinning, Kari; Moe, Vibeke & Walhovd, Kristine B (2016). Kognitiv utvikling fra 1 år til ungdomsalder hos personer født av mødre med opiat– eller blandingsmisbruk under svangerskapet.
• Slinning, Kari; Nygaard, Egil & Walhovd, Kristine B (2016). Barn og unge av mødre med rusproblemer. Hvordan går det med dem? Resultater fra 20 år med oppfølging.
• Nygaard, Egil; Walhovd, Kristine B; Slinning, Kari & Moe, Vibeke (2015). Hvordan går det med ungdom som ble utsatt for mødres opioid-og/eller blandingsmisbruk før de ble født?.
• Nygaard, Egil; Walhovd, Kristine B; Slinning, Kari & Moe, Vibeke (2015). Hvordan går det med ungdom som ble utsatt for mødres opioid-og/eller blandingsmisbruk før de ble født?.
• Tamnes, Christian Krog; Krogsrud, Stine Kleppe; Fjell, Anders Martin & Walhovd, Kristine B (2015). Regional development of hippocampal subfield volumes and its associations with cognition and memory.
• Backe-Hansen, Elisabeth; Walhovd, Kristine B & Huang, Lihong (2014). Kjønnsforskjeller i skoleprestasjoner: En kunnskapsoppsummering. NOVA Rapport. 5.
• Haabrekke, Kristin Johanne; Siqveland, Torill; Smith, Lars; Wentzel-Larsen, Tore; Walhovd, Kristine B & Moe, Vibeke (2014). Early language skills in children born to mothers with substance abuse and psychiatric problems.
• Karadottir, Ragnhildur & Walhovd, Kristine B (2014). The CNS White Matter. Neuroscience.  ISSN 0306-4522.  276, s 1 . doi: 10.1016/j.neuroscience.2014.03.010
• Lundervold, Astri; Walhovd, Kristine B; Rönnberg, Jerker & Sundet, Kjetil Søren (2014). New perspectives in neuropsychology. Scandinavian Journal of Psychology.  ISSN 0036-5564.  55(3), s 187- 188 . doi: 10.1111/sjop.12135
• Nygaard, Egil & Walhovd, Kristine B (2014). Hvordan går det med ungdom som ble utsatt for blandingsmisbruk før de ble født?.
• Walhovd, Kristine B & Nygaard, Egil (2014). Hjerne og kognitiv utvikling - perspektiver fra flere utvalg barn uten etablert risiko og barn født av mødre med rusproblemer.
• Walhovd, Kristine B & Nygaard, Egil (2014). Nevrokognitiv utvikling: Dimensjonalitet og langtidsperspektiver.

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