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Genetiske og utviklingsmessige mekanismer i alvorlig psykisk lidelse

Om prosjektet

Alvorlig psykisk sykdom er blant de viktigste årsakene til nedsatt funksjonsnivå og uførhet. Psykotiske lidelser, inkludert schizofreni og bipolar lidelse har høy arvelighet og symptomene utvikles vanligvis i ungdomsårene eller tidlig i voksenlivet. Til tross for stor forskningsinnsats de siste årene er årsaker og mekanismer fortsatt ikke fullt ut forstått. Denne manglende kunnskapen har forsinket utviklingen av nye og effektive behandlingsmetoder.

Mål

Prosjektets hovedmål er å bidra til økt kunnskap om årsakene til alvorlige psykiske lidelser, som vil kunne bidra til å bedre forebygging og behandling.

Nyere forskning som har benyttet avansert teknologi for avbildning av hjernen har vist at sykdomsutviklingen kan relateres til endringer i hjernens struktur og funksjon, og at disse endringene i hjernen til en viss grad kan tilskrives variasjon i arveanlegget. Ved å sammenligne hjerneavbildningsdata fra personer med alvorlig psykisk lidelse med friske personer i ulike alderstrinn, ønsker vi å identifisere og kartlegge utviklingsforløpene til nettverkene i hjernen som er involvert i utviklingen av schizofreni og bipolar lidelse. Videre vil vi avdekke de spesifikke delene av arveanlegget som påvirker disse nettverkene, samt undersøke den genetiske overlappen mellom hjernenettverk og risiko for mentale lidelser. Økt kunnskap om de utviklingsmessige prosessene i hjernen som kan gi økt risiko for utvikling av psykisk sykdom senere i livet kan gi viktig holdepunkter for bedre diagnostisering, mer presise prognoser, samt ny behandling.

Finansiering

Prosjektet er finansiert av Norges Forskningsråd (FRIMEDBIO - Unge forskertalenter) 2016 - 2020.

Samarbeid

Psykologisk institutt og Norsk senter for forskning på mentale lidelser (NORMENT).

Publikasjoner

  • Ivan Maximov & Sebastian Vellmer (2019). Isotropically weighted intravoxel incoherent motion brain imaging at 7T.. Magnetic Resonance Imaging.  ISSN 0730-725X.  57, s 124- 132
  • Emanuel Schwarz; Nhat Trung Doan; Giulio Pergola; Lars Tjelta Westlye; Tobias Kaufmann; Thomas Wolfers; Ralph Brecheisen; Tiziana Quarto; Alex J. Ing; Pasquale di Carlo; Tiril Pedersen Gurholt; Robbert L. Harms; Quentin Noirhomme; Torgeir Moberget; Ingrid Agartz; Ole Andreas Andreassen; Marcella Bellani; Alessandro Bertolino; Giuseppe Blasi; Paolo Brambilla; Jan K. Buitelaar; Simon Cervenka; Lena Flyckt; Sophia Frangou; Barbara Franke; Jeremy Hall; Dirk J. Heslenfeld; Peter Kirsch; Andrew M. McIntosh; Markus M. Nöthen; Andreas Papassotiropoulos; Dominique J.F. de Quervain; Marcella Rietschel; Gunter Schumann; Heike Tost; Stephanie H. Witt; Mathias Zink & Andreas Meyer-Lindenberg (2019). Reproducible grey matter patterns index a multivariate, global alteration of brain structure in schizophrenia and bipolar disorder. Translational psychiatry.  ISSN 2158-3188.  9
  • Nathalia Zak; Erlend Bøen; Birgitte Boye; Ole Andreas Andreassen; Nhat Trung Doan; Ulrik Fredrik Malt; Lars Tjelta Westlye & Torbjørn Elvsåshagen (2019). Mood episodes are associated with increased cortical thinning: A longitudinal study of bipolar disorder type II. Bipolar Disorders.  ISSN 1398-5647.
  • Ivan Maximov; Dag Alnæs & Lars Tjelta Westlye (2019). Towards an optimised processing pipeline for diffusion magnetic resonance imaging data: Effects of artefact corrections on diffusion metrics and their age associations in UK Biobank. Human Brain Mapping.  ISSN 1065-9471.  40, s 4146- 4162
  • Elena Kremneva; Ludmila Legostaeva; Sofya Morozova; Dmitry Sergeev; Dmitry Sinitsyn; Elizaveta Iazeva; Aleksandr Suslin; Natalia Suponeva; Marina Krotenkova; Michael Piradov & Ivan Maximov (2019). Feasibility of Non-Gaussian Diffusion Metrics in Chronic Disorders of Consciousness. Brain Sciences.  ISSN 2076-3425.  9, s 123
  • Nicolas Moutal; Ivan Maximov & Denis Grebenkov (2019). Probing surface-to-volume ratio of an anisotropic medium by diffusion NMR with general gradient encoding. IEEE Transactions on Medical Imaging.  ISSN 0278-0062.  38, s 2507- 2522
  • Daniel Quintana; Jaroslav Rokicki; Dennis van der Meer; Dag Alnæs; Tobias Kaufmann; Aldo Còrdova Palomera; Ingrid Dieset; Ole Andreas Andreassen & Lars Tjelta Westlye (2019). Oxytocin pathway gene networks in the human brain. Nature Communications.  ISSN 2041-1723.  10
  • Torgeir Moberget; Dag Alnæs; Tobias Kaufmann; Nhat Trung Doan; Aldo Còrdova Palomera; Linn Christin Bonaventure Norbom; Jaroslav Rokicki; Dennis van der Meer; Ole Andreas Andreassen & Lars Tjelta Westlye (2019). Cerebellar Gray Matter Volume Is Associated With Cognitive Function and Psychopathology in Adolescence. Biological Psychiatry.  ISSN 0006-3223.  86, s 65- 75
  • Tobias Kaufmann; Dennis van der Meer; Nhat Trung Doan; Emanuel Schwarz; Martina Jonette Lund; Ingrid Agartz; Dag Alnæs; Deanna M. Barch; Ramona Baur-Streubel; Alessandro Bertolino; Francesco Bettella; Mona K. Beyer; Erlend Bøen; Stefan Borgwardt; Christine Lycke Brandt; Jan Buitelaar; Elisabeth Gulowsen Celius; Simon Cervenka; Annette Conzelmann; Aldo Còrdova Palomera; Anders Dale; Dominique J.F. de Quervain; Pasquale di Carlo; Srdjan Djurovic; Erlend Solberg Dørum; Sarah Eisenacher; Torbjørn Elvsåshagen; Thomas Espeseth; Helena Fatouros-Bergman; Lena Flyckt; Barbara Franke; Oleksandr Frei; Beathe Haatveit; Asta Håberg; Hanne Flinstad Harbo; Catharina A Hartman; Dirk J Heslenfeld; Pieter J Hoekstra; Einar August Høgestøl; Terry L. Jernigan; Rune Jonassen; Erik Gunnar Jönsson; Peter Kirsch; Iwona Kłoszewska; Knut-Kristian Kolskår; Nils Inge Landrø; Stephanie Le Hellard; Klaus-Peter Lesch; Simon Lovestone; Arvid Lundervold; Astri Lundervold; Luigi Angelo Maglanoc; Ulrik Fredrik Malt; Patrizia Mecocci; Ingrid Melle; Andreas Meyer-Lindenberg; Torgeir Moberget; Linn Christin Bonaventure Norbom; Jan Egil Nordvik; Lars Nyberg; Jaap Oosterlaan; Marco Papalino; Andreas Papassotiropoulos; Paul Pauli; Giulio Pergola; Karin Ester Torun Persson; Geneviève Richard; Jaroslav Rokicki; Anne-Marthe Sanders; Geir Selbæk; Alexey A. Shadrin; Olav Bjerkehagen Smeland; Hilkka Soininen; Piotr Sowa; Vidar Martin Steen; Magda Tsolaki; Kristine Moe Ulrichsen; Bruno Vellas; Lei Wang; Eric Westman; Georg C. Ziegler; Mathias Zink; Ole Andreas Andreassen & Lars Tjelta Westlye (2019). Common brain disorders are associated with heritable patterns of apparent aging of the brain. Nature Neuroscience.  ISSN 1097-6256.  22, s 1617- 1623
  • Steve Smith; Eugene Duff; Adrian Groves; Thomas E. Nichols; Saad Jbabdi; Lars Tjelta Westlye; Christian Krog Tamnes; Andreas Engvig; Kristine B Walhovd; Anders Martin Fjell; Heidi Johansen-Berg & Gwenaëlle Douaud (2019). Structural variability in the human brain reflects fine-grained functional architecture at the population level. Journal of Neuroscience.  ISSN 0270-6474.  39, s 6136- 6149
  • Luigi Angelo Maglanoc; Tobias Kaufmann; Rune Jonassen; Eva Hilland; Dani Beck; Nils Inge Landrø & Lars Tjelta Westlye (2019). Multimodal fusion of structural and functional brain imaging in depression using linked independent component analysis. Human Brain Mapping.  ISSN 1065-9471.
  • Derrek Hibar; Lars Tjelta Westlye; Nhat Trung Doan; Neda Jahanshad; J. W. Cheung; Christopher R K Ching; Amelia Versace; A Bilderbeck; Anne Uhlmann; B Mwangi; B Krämer; B Overs; Cecilie Bhandari Hartberg; Christoph Abé; Danai Dima; Dominik Grotegerd; Emma Sprooten; Erlend Bøen; Enrique Jimenez; Fleur M. Howells; G Delvecchio; H Temmingh; J Starke; JRC Almeida; JM Goikolea; J Houenou; Lauren M. Beard; L Rauer; Lucija Abramovic; M. Bonnin; MF Ponteduro; M Keil; MM Rive; N Yao; N Yalin; P Najt; PG Rosa; Ronny Redlich; S Trost; Saskia Hagenaars; SC Fears; S Alonso-Lana; TGM Van Erp; Thomas Nickson; TM Chaim-Avancini; TB Meier; Torbjørn Elvsåshagen; Unn Kristin H. Haukvik; Who-Seung Lee; AH Schene; AJ Lloyd; AH Young; Allison C Nugent; AM Dale; Andrea Pfennig; AM McIntosh; Beny Lafer; BT Baune; CJ Ekman; CA Zarate; CE Bearden; C Henry; Christian Simhandl; C McDonald; C Bourne; DJ Stein; DH Wolf; DM Cannon; DC Glahn; DJ Veltman; E Pomarol-Clotet; E Vieta; EJ Canales-Rodriguez; FG Nery; FLS Duran; GF Busatto; G Roberts; GD Pearlson; GM Goodwin; H Kugel; HC Whalley; HG Ruhe; JC Soares; JM Fullerton; JK Rybakowski; Jonathan Savitz; KT Chaim; Mar Fatjo-Vilas; MG Soeiro-de-Souza; MP Boks; MV Zanetti; MCG Otaduy; MS Schaufelberger; Martin Alda; Martin Ingvar; ML Phillips; MJ Kempton; M Bauer; M Landén; NS Lawrence; NEM Van Haren; NR Horn; NB Freimer; Oliver Gruber; PR Schofield; PB Mitchell; RS Kahn; R Lenroot; R Machado-Vieira; RA Ophoff; S Sarró; Sophia Frangou; TD Satterthwaite; Tomas Hajek; Udo Dannlowski; Ulrik Fredrik Malt; Volker Arolt; WF Gattaz; WC Drevets; Xavier Caseras; Ingrid Agartz; PM Thompson & Ole Andreas Andreassen (2018). Cortical abnormalities in bipolar disorder: An MRI analysis of 6503 individuals from the ENIGMA Bipolar Disorder Working Group. Molecular Psychiatry.  ISSN 1359-4184.  23, s 932- 942
  • S Kelly; Neda Jahanshad; A Zalesky; Kochunov P; Ingrid Agartz; C Alloza; Ole Andreas Andreassen; C Arango; Nerisa Banaj; S Bouix; CA Bousman; RM Brouwer; J Bruggemann; Juan R Bustillo; Wiepke Cahn; Vince Calhoun; Dara M Cannon; Vaughan J. Carr; Stanley V. Catts; J Chen; JX Chen; X Chen; C Chiapponi; KK Cho; Valentina Ciullo; A Corvin; Benedicto Crespo-Facorro; V Cropley; Pietro De Rossi; CM Diaz-Caneja; EW Dickie; S Ehrlich; FM Fan; Joshua Faskowitz; Helena Fatouros-Bergman; Lena Flyckt; JM Ford; JP Fouche; Masaki Fukunaga; M Gill; DC Glahn; Randy L Gollub; ED Goudzwaard; H Guo; RE Gur; RC Gur; Tiril Pedersen Gurholt; Ryota Hashimoto; SN Hatton; FA Henskens; DP Hibar; IB Hickie; LE Hong; Jan Horacek; FM Howells; Hilleke E Hulshoff Pol; CL Hyde; D Isaev; Assen Jablensky; PR Jansen; J Janssen; Erik Gunnar Jönsson; LA Jung; RS Kahn; Z Kikinis; K Liu; Paul Klauser; C Knöchel; M Kubicki; Jim Lagopoulos; C Langen; Stephen M Lawrie; R Lenroot; KO Lim; Carlos Lopez-Jaramillo; A Lyall; V Magnotta; RCW Mandl; DH Mathalon; RW McCarley; Simon McCarthy-Jones; C McDonald; S McEwen; A McIntosh; T Melicher; RI Mesholam-Gately; PT Michie; Bryan J. Mowry; BA Mueller; DT Newell; P O'donnell; V Oertel-Knöchel; L Oestreich; SA Paciga; Christos Pantelis; O Pasternak; Godfrey D Pearlson; GR Pellicano; A Pereira; J Pineda Zapata; Fabrizio Piras; SG Potkin; Adrian Preda; PE Rasser; DR Roalf; R Roiz; A Roos; D Rotenberg; TD Satterthwaite; P Savadjiev; Ulrich Schall; RJ Scott; ML Seal; LJ Seidman; C Shannon Weickert; CD Whelan; ME Shenton; JS Kwon; Gianfranco Spalletta; F Spaniel; Emma Sprooten; M Stäblein; DJ Stein; S Sundram; Y Tan; S Tan; S Tang; HS Temmingh; Lars Tjelta Westlye; Siren Tønnesen; Diana Tordesillas-Gutierrez; Nhat Trung Doan; Jatin G. Vaidya; NEM Van Haren; CD Vargas; D Vecchio; D Velakoulis; Aristotle N. Voineskos; JQ Voyvodic; Z Wang; P Wan; D Wei; TW Weickert; Heather Clare Whalley; T White; TJ Whitford; JD Wojcik; HUA XIANG; Z Xie; Hidenaga Yamamori; F Yang; N Yao; G. Zhang; J Zhao; Theo G M Van Erp; J Turner; PM Thompson & Gary Donohoe (2018). Widespread white matter microstructural differences in schizophrenia across 4322 individuals: Results from the ENIGMA Schizophrenia DTI Working Group. Molecular Psychiatry.  ISSN 1359-4184.  23, s 1261- 1269
  • Dag Alnæs; Tobias Kaufmann; Nhat Trung Doan; Aldo Còrdova Palomera; Yunpeng Wang; Francesco Bettella; Torgeir Moberget; Ole Andreas Andreassen & Lars Tjelta Westlye (2018). Association of Heritable Cognitive Ability and Psychopathology With White Matter Properties in Children and Adolescents. JAMA psychiatry.  ISSN 2168-6238.  75, s 287- 295
  • Luigi Angelo Maglanoc; Nils Inge Landrø; Rune Jonassen; Tobias Kaufmann; Aldo Còrdova Palomera; Eva Hilland & Lars Tjelta Westlye (2018). Data-driven clustering reveals a link between symptoms and functional brain connectivity in depression. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging.  ISSN 2451-9022.  4, s 16- 26
  • Sook-Lei Liew; Julia M. Anglin; Nick W. Banks; Matt Sondag; Kaori L. Ito; Hosung Kim; Jennifer Chan; Joyce Ito; Connie Jung; Nima Khoshab; Stephanie Lefebvre; William Nakamura; David Saldaña; Allie Schmiesing; Cathy Tran; Danny Vo; Tyler Ard; Panthea Heydari; Bokkyu Kim; Lisa Aziz-Zadeh; Steven C. Cramer; Jingchun Liu; Surjo Soekadar; Jan Egil Nordvik; Lars Tjelta Westlye; Junping Wang; Carolee Winstein; Chunshui Yu; Lei Ai; Bonhwang Koo; R. Cameron Craddock; Michael Peter Milham; Matthew Lakich; Amy Pienta & Alison Stroud (2018). A large, open source dataset of stroke anatomical brain images and manual lesion segmentations. Scientific Data.  ISSN 2052-4463.  5
  • Aldo Còrdova Palomera; Tobias Kaufmann; Francesco Bettella; Yunpeng Wang; Nhat Trung Doan; Dennis van der Meer; Dag Alnæs; Jaroslav Rokicki; Torgeir Moberget; Ida Elken Sønderby; Ole Andreas Andreassen & Lars Tjelta Westlye (2018). Effects of autozygosity and schizophrenia polygenic risk on cognitive and brain developmental trajectories. European Journal of Human Genetics.  ISSN 1018-4813.  26, s 1049- 1059
  • Theo G.M. Van Erp; Esther Walton; Derrek Hibar; Lianne Schmaal; Wenhao Jiang; David C. Glahn; Godfrey D. Pearlson; Nailin Yao; Masaki Fukunaga; Ryota Hashimoto; Naohiro Okada; Hidenaga Yamamori; Juan R. Bustillo; Vincent P. Clark; Ingrid Agartz; Bryon A. Mueller; Wiepke Cahn; Sonja M.C. de Zwarte; Hilleke E. Hulshoff Pol; René S. Kahn; Roel A. Ophoff; Neeltje E.M. van Haren; Ole Andreas Andreassen; Anders Dale; Nhat Trung Doan; Tiril Pedersen Gurholt; Cecilie Bhandari Hartberg; Unn Kristin H. Haukvik; Kjetil Nordbø Jørgensen; Trine Vik Lagerberg; Ingrid Melle; Lars Tjelta Westlye; Oliver Gruber; Bernd Kraemer; Anja Richter; David Zilles; Vince D. Calhoun; Benedicto Crespo-Facorro; Roberto Roiz-Santiañez; Diana Tordesillas-Gutiérrez; Carmel Loughland; Vaughan J. Carr; Stanley Catts; Vanessa L. Cropley; Janice M. Fullerton; Melissa J. Green; Frans A. Henskens; Assen Jablensky; Rhoshel K. Lenroot; Bryan J. Mowry; Patricia T. Michie; Christos Pantelis; Yann Quide; Ulrich Schall; Rodney J. Scott; Murray J. Cairns; Marc Seal; Paul A. Tooney; Paul E. Rasser; Gavin Cooper; Cynthia Shannon Weickert; Thomas W. Weickert; Derek W. Morris; Elliot Hong; Peter Kochunov; Lauren M. Beard; Raquel E. Gur; Ruben C. Gur; Theodore D Satterthwaite; Daniel H. Wolf; Aysenil Belger; Gregory G. Brown; Judith M. Ford; Fabio Macciardi; Daniel H. Mathalon; Daniel S. O'Leary; Steven G. Potkin; Adrian Preda; James Voyvodic; Kelvin O. Lim; Sarah McEwen; Fude Yang; Yunlong Tan; Shuping Tan; Zhiren Wang; Fengmei Fan; Jingxu Chen; Hong Xiang; Shiyou Tang; Hua Guo; Ping Wan; Dong Wei; Henry J. Bockholt; Stefan Ehrlich; Rick P.F. Wolthusen; Margaret D. King; Jody M. Shoemaker; Scott R. Sponheim; Lieuwe De Haan; Laura Koenders; Marise W. Machielsen; Therese van Amelsvoort; Dick J. Veltman; Francesca Assogna; Nerisa Banaj; Pietro de Rossi; Mariangela Iorio; Fabrizio Piras; Gianfranco Spalletta; Peter J. McKenna; Edith Pomarol-Clotet; Raymond Salvador; Aiden Corvin; Gary Donohoe; Sinead Kelly; Christopher D. Whelan; Erin W. Dickie; David Rotenberg; Aristotle N. Voineskos; Simone Ciufolini; Joaquim Radua; Paola Dazzan; Robin Murray; Tiago Reis Marques; Andrew Simmons; Stefan Borgwardt; Laura Egloff; Fabienne Harrisberger; Anita Riecher-Rössler; Renata Smieskova; Kathryn I. Alpert; Lei Wang; Erik Gunnar Jönsson; Sanne Koops; Iris Else Clara Sommer; Alessandro Bertolino; Aurora Bonvino; Annabella Di Giorgio; Emma Neilson; Andrew R. Mayer; Julia M. Stephen; Jun Soo Kwon; Je-Yeon Yun; Dara M. Cannon; Colm McDonald; Irina Lebedeva; Alexander S. Tomyshev; Tolibjohn Akhadov; Vasily Kaleda; Helena Fatouros-Bergman & Lena Flyckt (2018). Cortical brain abnormalities in 4474 individuals with schizophrenia and 5098 control subjects via the Enhancing Neuro Imaging Genetics Through Meta Analysis (ENIGMA) Consortium. Biological Psychiatry.  ISSN 0006-3223.
  • Kahori Kita; Jaroslav Rokicki; Shinichi Furuya; Takashi Sakamoto & Takashi Hanakawa (2018). Resting‐state basal ganglia network codes a motor musical skill and its disruption from dystonia. Movement Disorders.  ISSN 0885-3185.  s 1- 9
  • Jiayu Chen; Vince D. Calhoun; Dongdong Lin; Nora I. Perrone-Bizzozero; Juan R. Bustillo; Godfrey D. Pearlson; Steven G. Potkin; Theo G.M. Van Erp; Fabio Macciardi; Stefan Ehrlich; Beng-Choon Ho; Scott R. Sponheim; Lei Wang; Julia M. Stephen; Julia M. Mayer; Faith M. Hanlon; Rex E. Jung; Brett A. Clementz; Matcheri S. Keshavan; Elliot S. Gershon; John A. Sweeney; Carol A. Tamminga; Ole Andreas Andreassen; Ingrid Agartz; Lars Tjelta Westlye; Jing Sui; Yuhui Du; Jessica A. Turner & Jingyuan Liu (2018). Shared genetic risk of schizophrenia and gray matter reduction in 6p22.1. Schizophrenia Bulletin.  ISSN 0586-7614.  45, s 222- 232
  • Siren Tønnesen; Tobias Kaufmann; Nhat Trung Doan; Dag Alnæs; Aldo Còrdova Palomera; Dennis van der Meer; Jaroslav Rokicki; Torgeir Moberget; Tiril Pedersen Gurholt; Unn Kristin H. Haukvik; Torill Ueland; Trine Vik Lagerberg; Ingrid Agartz; Ole Andreas Andreassen & Lars Tjelta Westlye (2018). White matter aberrations and age-related trajectories in patients with schizophrenia and bipolar disorder revealed by diffusion tensor imaging. Scientific Reports.  ISSN 2045-2322.  8
  • Knut-Kristian Kolskår; Dag Alnæs; Tobias Kaufmann; Geneviéve´ Richard; Anne-Marthe Sanders; Kristine Moe Ulrichsen; Torgeir Moberget; Ole Andreas Andreassen; Jan Egil Nordvik & Lars Tjelta Westlye (2018). Key Brain Network Nodes Show Differential Cognitive Relevance and Developmental Trajectories during Childhood and Adolescence. eNeuro.  ISSN 2373-2822.  5, s 1- 13
  • Dennis van der Meer; Jaroslav Rokicki; Tobias Kaufmann; Aldo Còrdova Palomera; Torgeir Moberget; Dag Alnæs; Francesco Bettella; Oleksandr Frei; Nhat Trung Doan; Ida Elken Sønderby; Olav Bjerkehagen Smeland; Ingrid Agartz; Alessandro Bertolino; Janita Bralten; Christine Lycke Brandt; Jan K. Buitelaar; Srdjan Djurovic; Marjolein van Donkelaar; Erlend Solberg Dørum; Thomas Espeseth; Stephen V. Faraone; Guillén Fernandéz; Simon E. Fisher; Barbara Franke; Beathe Christin Haatveit; Catharina A. Hartman; Pieter J. Hoekstra; Asta Håberg; Erik Gunnar Jönsson; Knut-Kristian Kolskår; Stephanie Le Hellard; Martina Jonette Lund; Astri Lundervold; Arvid Lundervold; Ingrid Melle; Jennifer Monereo Sanchez; Linn Christin Bonaventure Norbom; Jan Egil Nordvik; Lars Nyberg; Jaap Oosterlaan; Marco Papalino; Andreas Papassotiropoulos; Giulio Pergola; Dominique J.F. de Quervain; Geneviéve´ Richard; Anne-Marthe Sanders; Pierluigi Selvaggi; Elena Shumskaya; Vidar Martin Steen; Siren Tønnesen; Kristine Moe Ulrichsen; Marcel P. Zwiers; Ole Andreas Andreassen & Lars Tjelta Westlye (2018). Brain scans from 21,297 individuals reveal the genetic architecture of hippocampal subfield volumes. Molecular Psychiatry.  ISSN 1359-4184.  s 1- 13
  • Ida Elken Sønderby; Omar Gustafsson; Nhat Trung Doan; Derrek Hibar; Sandra Martin-Brevet; Thomas Espeseth; Anja Vaskinn; Yunpeng Wang; Lars Tjelta Westlye; Sébastien Jacquemont; Srdjan Djurovic; Hreinn Stefánsson; Kári Stefánsson; Paul M. Thompson & Ole Andreas Andreassen (2018). Dose response of the 16p11.2 distal copy number variant on intracranial volume and basal ganglia. Molecular Psychiatry.  ISSN 1359-4184.  s 1- 16
  • Linn Christin Bonaventure Norbom; Nhat Trung Doan; Dag Alnæs; Tobias Kaufmann; Torgeir Moberget; Jaroslav Rokicki; Ole Andreas Andreassen; Lars Tjelta Westlye & Christian Krog Tamnes (2018). Probing brain developmental patterns of myelination and associations with psychopathology in youths using gray/white matter contrast. Biological Psychiatry.  ISSN 0006-3223.
  • Tobias Kaufmann; Dag Alnæs; Christine Lycke Brandt; Francesco Bettella; Srdjan Djurovic; Ole Andreas Andreassen & Lars Tjelta Westlye (2018). Stability of the Brain Functional Connectome Fingerprint in Individuals With Schizophrenia. JAMA psychiatry.  ISSN 2168-6238.
  • Geneviève Richard; Knut-Kristian Kolskår; Anne-Marthe Sanders; Tobias Kaufmann; Anders Petersen; Nhat Trung Doan; Jennifer Monereo Sanchez; Dag Alnæs; Kristine Moe Ulrichsen; Erlend Solberg Dørum; Ole Andreas Andreassen; Jan Egil Nordvik & Lars Tjelta Westlye (2018). Assessing distinct patterns of cognitive aging using tissue-specific brain age prediction based on diffusion tensor imaging and brain morphometry. PeerJ.  ISSN 2167-8359.
  • Aldo Còrdova Palomera; Tobias Kaufmann; Karin Persson; Dag Alnæs; Nhat Trung Doan; Torgeir Moberget; Martina Jonette Lund; Maria Lage Barca; Andreas Engvig; Anne Brækhus; Knut Engedal; Ole Andreas Andreassen; Geir Selbæk & Lars Tjelta Westlye (2017). Disrupted global metastability and static and dynamic brain connectivity across individuals in the Alzheimer's disease continuum. Scientific Reports.  ISSN 2045-2322.  7, s 1- 14
  • Tobias Kaufmann; Dag Alnæs; Christine Lycke Brandt; Nhat Trung Doan; Karolina Kauppi; Francesco Bettella; Trine Vik Lagerberg; Akiah Ottesen Berg; Srdjan Djurovic; Ingrid Agartz; Ingrid Melle; Torill Ueland; Ole Andreas Andreassen & Lars Tjelta Westlye (2017). Task modulations and clinical manifestations in the brain functional connectome in 1615 fMRI datasets. NeuroImage.  ISSN 1053-8119.  147, s 243- 252
  • Lars Tjelta Westlye; Tobias Kaufmann; Dag Alnæs; Ingunn Riise Hullstein & Astrid Bjørnebekk (2017). Brain connectivity aberrations in anabolic-androgenic steroid users. NeuroImage: Clinical.  ISSN 2213-1582.  13, s 62- 69
  • Nhat Trung Doan; Andreas Engvig; Karin Persson; Dag Alnæs; Tobias Kaufmann; Jaroslav Rokicki; Aldo Còrdova Palomera; Torgeir Moberget; Anne Brækhus; Maria Lage Barca; Knut Engedal; Ole Andreas Andreassen; Geir Selbæk & Lars Tjelta Westlye (2017). Dissociable diffusion MRI patterns of white matter microstructure and connectivity in Alzheimer's disease spectrum. Scientific Reports.  ISSN 2045-2322.  7:45131
  • Torgeir Hellstrøm; Tobias Kaufmann; Nada Andelic; Helene L. Søberg; Solrun Sigurdardottir; Eirik Helseth; Ole Andreas Andreassen & Lars Tjelta Westlye (2017). Predicting outcome 12 months after mild traumatic brain injury in patients admitted to a neurosurgery service. Frontiers in Neurology.  ISSN 1664-2295.  8:125, s 1- 12
  • Tobias Kaufmann; Dag Alnæs; Nhat Trung Doan; Christine Lycke Brandt; Ole Andreas Andreassen & Lars Tjelta Westlye (2017). Delayed stabilization and individualization in connectome development are related to psychiatric disorders. Nature Neuroscience.  ISSN 1097-6256.  20, s 513- 515
  • Nhat Trung Doan; Andreas Engvig; Krystal Zaske; Karin Persson; Martina Jonette Lund; Tobias Kaufmann; Aldo Còrdova Palomera; Dag Alnæs; Torgeir Moberget; Anne Brækhus; Maria Lage Barca; Jan Egil Nordvik; Knut Engedal; Ingrid Agartz; Geir Selbæk; Ole Andreas Andreassen & Lars Tjelta Westlye (2017). Distinguishing early and late brain aging from the Alzheimer's disease spectrum: Consistent morphological patterns across independent samples. NeuroImage.  ISSN 1053-8119.  158, s 282- 295
  • Torgeir Hellstrøm; Lars Tjelta Westlye; Tobias Kaufmann; Nhat Trung Doan; Helene L. Søberg; Solrun Sigurdardottir; Wibeke Nordhøy; Eirik Helseth; Ole Andreas Andreassen & Nada Andelic (2017). White matter microstructure is associated with functional, cognitive and emotional symptoms 12 months after mild traumatic brain injury. Scientific Reports.  ISSN 2045-2322.  7
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  • Hiroki Togo; Jaroslav Rokicki; Kenji Yoshinaga; Tatushiro Hisatsune; Hiroshi Matsuda; Nobuhiko Haga & Takashi Hanakawa (2017). Effects of Field-Map Distortion Correction on Resting State Functional Connectivity MRI. Frontiers in Neuroscience.  ISSN 1662-4548.  11
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  • Irene Voldsbekk; Daniël Thomas Heimen Roelfs; Atle Bjørnerud; Inge Rasmus Groote & Ivan Maximov (2019). White matter microstructure changes as a function of time-of-day: a biomarker of accumulating sleep pressure?.
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Publisert 19. aug. 2016 13:36 - Sist endret 11. jan. 2018 13:45