Clinical Neuroscience Research Group
Can neuroscience help us understand the development and treatment of mental illness in individual patients?
About the group
Professor Nils Inge Landrø is the leader of the group. The group was established in 2014. The members of the group mainly have their educational background in psychology.
The main focus of the group's research is how knowledge of cognitive and clinical neuroscience can be used to understand the development and treatment of mental illness. By understanding the mechanisms that cause psychological complaints and how these are similar, rather than different, across different diagnosis, we want treatment to target these mechanisms. By identifying factors that maintain the symptoms of each patient, the treatment can be tailored to individual symptom profiles rather than diagnosis. An aim is to integrate new technology in the treatment of psychological disorders.
The combination of neuroscientific knowledge and randomized controlled studies makes us part of the international research frontier.
In previous and ongoing projects, we have studied cognitive control functions and mood, as well as genes that regulate the interaction between cognition and emotion.
This kind of research can provide new insights into how mood disorders (depression) develops and sustains over time. The projects will provide new knowledge of the principles of treatment and prevention.
Recently, the group has conducted a big randomized controlled trial that investigates the effect of change in affective bias as relapse prevention of depression. This project has thus far resulted in five articles in internationally renowned peer-reviewed journals and three doctoral dissertations.
Other topics are impulsivity and impulsivity disorders, related to addiction and personality disorders.
Through the cooperation with other research environments, the group is also engaged in studies related to pain associated with neurological diseases and injuries.
Researchers work with several colleagues internally at the Department of Psychology, and various external institutions both nationally and internationally: OsloMet, NORMENT, Vestre Viken HF, National Competence Centre for Complex Symptom Disorders (St. Olav's Hospital / NTNU), Hospital of Southern Norway, Diakonhjemmet Hospital, Lovisenberg hospital, Interventional Centre and Neurological department at OUS.
Key international partners are Professor II Catherine J Harmer (University of Oxford), Professor Alexander Heeren (University of Louvain) and Professor Jutta Joormann (Yale University) and Professor Ernst Koster (University of Gent).
Both traditional neuropsychological and psychometric testing methods, experimental cognitive paradigms, as well as mapping of eye movements and brain imaging are being used. Other physiological measures like cortisol and heart rate monitoring are also in use. Recently, we applied smartphones for registering daily fluctuations in symptoms.