A history of hope and disaster
For decades, a lack of safe and efficient treatment meant that rheumatologists and their patients were caught between a devastating disease and harmful medicines, writes Jonas Kure Buer in an article at Sciencenordic.
"Researchers, physicians, bureaucrats, and others could hence present new preparations as non-steroidal, and neither they nor their clients or patients needed concern themselves with fears for side effects of the kind the cortisone preparations were now known to cause.
Within a few years, Whitehouse’ pragmatic formula “non-steroid” became a fixed expression. Soon the expression “non-steroidal anti-inflammatory drug” gained the kind of currency that would allow its acronym “NSAID” to become a word on its own. Gradually it became difficult even to imagine a conversation about arthritis or rheumatology without these five letters.
Yet, during the 1980s and 1990s, evidence accumulated that also NSAIDs – the supposedly safe alternative to steroids – had their own severe side effects."
Read the whole article at sciencenordic.com.