Anders Martin Fjell

• Bråthen, Anne Cecilie Sjøli; de Lange, Ann-Marie Glasø; Fjell, Anders Martin & Walhovd, Kristine B (2020). Risk- and protective factors for memory plasticity in aging. Aging, Neuropsychology and Cognition.  ISSN 1382-5585. . doi: https://doi.org/10.1080/13825585.2020.1727834
• Fjell, Anders Martin; Sederevicius, Donatas; Sneve, Markus Handal; de Lange, Ann-Marie Glasø; Bråthen, Anne Cecilie Sjøli; Idland, Ane-Victoria; Watne, Leiv Otto; Wang, Yunpeng; Reinbold, Céline Sonja; Blennow, Kaj; Zetterberg, Henrik; Hong, S; Bertram, Lars & Walhovd, Kristine B (2020). Self-reported sleep problems are related to amyloid deposition in cortical regions with high HOMER1 gene expression. Cerebral Cortex.  ISSN 1047-3211. Fulltekst i vitenarkiv.
• Idland, Ane-Victoria; Sala-Llonch, Roser; Watne, Leiv; Brækhus, Anne; Hansson, Oskar; Blennow, Kaj; Zetterberg, Henrik; Sørensen, Øystein; Walhovd, Kristine B; Wyller, Torgeir Bruun & Fjell, Anders Martin (2020). Biomarker Profiling Beyond Amyloid and Tau: Cerebrospinal Fluid Markers, Hippocampal Atrophy, and Memory Change in Cognitively Unimpaired Older Adults. Neurobiology of Aging.  ISSN 0197-4580.  93 . doi: 10.1016/j.neurobiolaging.2020.04.002 Vis sammendrag

  Brain changes occurring in aging can be indexed by biomarkers. We used cluster analysis to identify subgroups of cognitively unimpaired individuals (n = 99, 64-93 years) with different profiles of the cerebrospinal fluid biomarkers beta amyloid 1-42 (Aβ42), phosphorylated tau (P-tau), total tau, chitinase-3-like protein 1 (YKL-40), fatty acid binding protein 3 (FABP3), and neurofilament light (NFL). Hippocampal volume and memory were assessed across multiple follow-up examinations covering up to 6.8 years. Clustering revealed one group (39%) with more pathological concentrations of all biomarkers, which could further be divided into one group (20%) characterized by tauopathy and high FABP3 and one (19%) by brain β-amyloidosis, high NFL, and slightly higher YKL-40. The clustering approach clearly outperformed classification based on Aβ42 and P-tau alone in prediction of memory decline, with the individuals with most tauopathy and FABP3 showing more memory decline, but not more hippocampal volume change. The results demonstrate that older adults can be classified based on biomarkers beyond amyloid and tau, with improved prediction of memory decline

• Langnes, Espen; Sneve, Markus Handal; Sederevicius, Donatas; Amlien, Inge Kasbohm; Walhovd, Kristine B & Fjell, Anders Martin (2020). Anterior and posterior hippocampus macro‐ and microstructure across the lifespan in relation to memory—A longitudinal study. Hippocampus.  ISSN 1050-9631.  s 1- 15 . doi: 10.1002/hipo.23189
• Amlien, Inge Kasbohm; Sneve, Markus Handal; Vidal-Piñeiro, Didac; Walhovd, Kristine B & Fjell, Anders Martin (2019). Elaboration Benefits Source Memory Encoding Through Centrality Change. Scientific Reports.  ISSN 2045-2322.  9(1), s 1- 13 . doi: 10.1038/s41598-019-39999-1 Fulltekst i vitenarkiv.
• Bjørnebekk, Astrid; Westlye, Lars Tjelta; Walhovd, Kristine B; Jørstad, Marie Lindvik; Sundset, Øyvind & Fjell, Anders Martin (2019). Cognitive Performance and Structural Brain Correlates in Long-Term Anabolic-Androgenic Steroid Exposed and Nonexposed Weightlifters. Neuropsychology.  ISSN 0894-4105.  33(4), s 547- 559 . doi: 10.1037/neu0000537
• Ferschmann, Lia; Vijayakumar, Nandita; Grydeland, Håkon; Øverbye, Knut; Sederevicius, Donatas; Due-Tønnessen, Paulina; Fjell, Anders Martin; Walhovd, Kristine B; Pfeifer, Jennifer H. & Tamnes, Christian Krog (2019). Prosocial behavior relates to the rate and timing of cortical thinning from adolescence to young adulthood. Developmental Cognitive Neuroscience.  ISSN 1878-9293.  40:100734, s 1- 8 . doi: 10.1016/j.dcn.2019.100734 Fulltekst i vitenarkiv.
• Fjell, Anders Martin; Chen, Chi-Hua Chen; Sederevicius, Donatas; Sneve, Markus Handal; Grydeland, Håkon; Krogsrud, Stine Kleppe; Amlien, Inge Kasbohm; Ferschmann, Lia; Ness, Hedda; Folvik, Line; Beck, Dani; Mowinckel, Athanasia Monika; Tamnes, Christian Krog; Westerhausen, René; Håberg, Asta; Dale, Anders M & Walhovd, Kristine B (2019). Continuity and discontinuity in human cortical development and change from embryonic stages to old age. Cerebral Cortex.  ISSN 1047-3211.  29(9), s 3879- 3890 . doi: 10.1093/cercor/bhy266 Fulltekst i vitenarkiv.
• Fjell, Anders Martin; Sneve, Markus Handal; Sederevicius, Donatas; Sørensen, Øystein; Krogsrud, Stine Kleppe; Mowinckel, Athanasia Monika & Walhovd, Kristine B (2019). Volumetric and microstructural regional changes of the hippocampus underlying development of recall performance after extended retention intervals. Developmental Cognitive Neuroscience.  ISSN 1878-9293.  40:100723, s 1- 12 . doi: 10.1016/j.dcn.2019.100723 Fulltekst i vitenarkiv.
• Fjell, Anders Martin; Sørensen, Øystein; Amlien, Inge Kasbohm; Bartrés-Faz, David; Bros, Didac Macia; Buchmann, Nikolaus; Demuth, Ilja; Drevon, Christian A; duzel, Sandra; Ebmeier, K P; Idland, Ane-Victoria; Kietzmann, Tim C; Kievit, Rogier; Kühn, Simone; Lindenberger, Ulman; Mowinckel, Athanasia Monika; Nyberg, Lars Erik; Price, Darren; Sexton, Claire; Sole-Padulles, Cristina; Pudas, Sara; Sederevicius, Donatas; Suri, Sana; Wagner, Gerd; Watne, Leiv Otto; Westerhausen, René; Zsoldos, Eniko & Walhovd, Kristine B (2019). Self-reported sleep relates to hippocampal atrophy across the adult lifespan – results from the Lifebrain consortium. Sleep.  ISSN 0161-8105. . doi: 10.1093/sleep/zsz280 Fulltekst i vitenarkiv.
• Friedman, Barbara Bodorkos; Suri, Sana; Sole-Padulles, Cristina; Düzel, Sandra; Drevon, Christian A; Baaré, William F. C.; Bartrés-Faz, David; Fjell, Anders Martin; Johansen-Berg, Heidi; Madsen, Kathrine S.; Nyberg, Lars; Penninx, Brenda W.J.H.; Sexton, Claire; Walhovd, Kristine B; Zsoldos, Enikő & Ljøsne, Isabelle Sylvie Budin (2019). Are People Ready for Personalized Brain Health? Perspectives of Research Participants in the Lifebrain Consortium. The gerontologist.  ISSN 0016-9013. . doi: 10.1093/geront/gnz155 Fulltekst i vitenarkiv.
• Grydeland, Håkon; Vértes, Petra; Váša, František; Romero-Garcia, Rafael; Whitaker, Kirstie; Aaron F., Alexander-Bloch; Bjørnerud, Atle; Patel, Ameera X.; Sederevicius, Donatas; Tamnes, Christian Krog; Westlye, Lars Tjelta; White, Simon; Walhovd, Kristine B; Fjell, Anders Martin & Bullmore, Edward T. (2019). Waves of Maturation and Senescence in Microstructural MRI Markers of Human Cortical Myelination over the Lifespan. Cerebral Cortex.  ISSN 1047-3211.  29(3), s 1369- 1381 . doi: 10.1093/cercor/bhy330 Fulltekst i vitenarkiv.
• Halaas, Nathalie Bodd; Henjum, Kristi; Blennow, Kaj; Dakhil, Shams; Idland, Ane-Victoria; Nilsson, Lars; Sederevicius, Donatas; Vidal-Piñeiro, Didac; Walhovd, Kristine B; Wyller, Torgeir Bruun; Zetterberg, Henrik; Watne, Leiv & Fjell, Anders Martin (2019). CSF sTREM2 and Tau Work Together in Predicting Increased Temporal Lobe Atrophy in Older Adults. Cerebral Cortex.  ISSN 1047-3211.  00, s 1- 12 . doi: 10.1093/cercor/bhz240
• Hauger, Lisa Evju; Westlye, Lars Tjelta; Fjell, Anders Martin; Walhovd, Kristine B & Bjørnebekk, Astrid (2019). Structural brain characteristics of anabolic-androgenic steroid dependence in men. Addiction.  ISSN 0965-2140.  s 1- 11 . doi: 10.1111/add.14629
• Nygaard, Egil; Slinning, Kari; Moe, Vibeke; Fjell, Anders Martin & Walhovd, Kristine B (2019). Mental health in youth prenatally exposed to opioids and poly-drugs and raised in permanent foster/adoptive homes: A prospective longitudinal study. Early Human Development.  ISSN 0378-3782.  140:104910, s 1- 8 . doi: 10.1016/j.earlhumdev.2019.104910 Fulltekst i vitenarkiv. Vis sammendrag

  Abstract Background Little is known about the mental health of prenatally opioid- and polydrug-exposed youth raised in foster/adoptive families. Aim To compare mental health problems among two groups of youth, one prenatally drug-exposed group with participants who were mainly placed in permanent foster or adoptive homes in early infancy and a group without known prenatal risk factors who were raised by their birth parents. Methods The sample consisted of 45 drug-exposed and 48 nonexposed youth between 17 and 22 years old from an original sample of 136 followed since birth. An extended version of the Mini International Neuropsychiatric Interview was used to assess lifetime psychiatric disorder, and participants completed the Achenbach Adult Self-Report form and Cantril's Ladder of Life Satisfaction Scale. Results A higher proportion of the youth in the drug-exposed group had lifetime experiences with major depressive episodes, alcohol abuse and attention deficit, hyperactivity disorder (OR > 3, p ≤ .030). They scored higher on the aggressive behavior scale, had more sexual partners and were younger at their sexual debut (p ≤ .030). There were no group differences in current self-reported satisfaction with life. Conclusion Youth exposed to drugs prenatally continue to represent a risk group despite early placement in permanent foster and adoptive homes. The factors contributing to this elevated risk may be multifaceted and involve adverse prenatal conditions including but not limited to drug exposure, genetics, and postnatal environmental conditions. The results highlight the need for longitudinal follow-up in the transition to adulthood as well as qualified service provision for these youth and their families.

• Parker, Nadine; Vidal-Piñeiro, Didac; French, Leon; Shin, Jean; Adams, Hieab H.; Brodaty, Henry; Cox, Simon R; Deary, Ian; Fjell, Anders Martin; Frenzel, Stefan; Grabe, Hans; Hosten, Norbert; Ikram, Mohammad A.; jiang, jiyang; Knol, Maria J.; Mazoyer, Bernard; Mishra, Aniket; Sachdev, Perminder; salum, giovanni; Satizabal, Claudia L; Schmidt, Helena; Schmidt, Reinhold; Seshadri, Sudha; Schumann, Gunter; Volzke, Henry; Walhovd, Kristine B; Wen, Wei; Wittfeld, Katharina; Yang, Qiong; debette, stephanie; Pausova, Zdenka & Paus, Tomáš (2019). Corticosteroids and Regional Variations in Thickness of the Human Cerebral Cortex across the Lifespan. Cerebral Cortex.  ISSN 1047-3211. . doi: 10.1093/cercor/bhz108 Fulltekst i vitenarkiv.
• Roe, James Michael; Vidal-Piñeiro, Didac; Sneve, Markus Handal; Kompus, Kristiina; Greve, Douglas N.; Walhovd, Kristine B; Fjell, Anders Martin & Westerhausen, René (2019). Age-Related Differences in Functional AsymmetryDuring Memory Retrieval Revisited: No Evidence forContralateral Overactivation or Compensation. Cerebral Cortex.  ISSN 1047-3211.  0(0), s 1- 19 . doi: 10.1093/cercor/bhz153 Fulltekst i vitenarkiv.
• Smith, Steve; Duff, Eugene; Groves, Adrian; Nichols, Thomas E.; Jbabdi, Saad; Westlye, Lars Tjelta; Tamnes, Christian Krog; Engvig, Andreas; Walhovd, Kristine B; Fjell, Anders Martin; Johansen-Berg, Heidi & Douaud, Gwenaëlle (2019). Structural variability in the human brain reflects fine-grained functional architecture at the population level. Journal of Neuroscience.  ISSN 0270-6474.  39(31), s 6136- 6149 . doi: 10.1523/JNEUROSCI.2912-18.2019 Fulltekst i vitenarkiv.
• Sneve, Markus Handal; Grydeland, Håkon; Rosa, Marcello G P; Paus, Tomáš; Chaplin, Tristan; Walhovd, Kristine B & Fjell, Anders Martin (2019). High-expanding regions in primate cortical brain evolution support supramodal cognitive flexibility. Cerebral Cortex.  ISSN 1047-3211.  29(9), s 3891- 3901 . doi: 10.1093/cercor/bhy268 Fulltekst i vitenarkiv.
• Vidal-Piñeiro, Didac; Sneve, Markus Handal; Nyberg, Lars; Mowinckel, Athanasia Monika; Sederevicius, Donatas; Walhovd, Kristine B & Fjell, Anders Martin (2019). Maintained Frontal Activity Underlies High Memory Function Over 8 Years in Aging. Cerebral Cortex.  ISSN 1047-3211.  29(7), s 3111- 3123 . doi: 10.1093/cercor/bhy177 Fulltekst i vitenarkiv.
• Øverbye, Knut; Walhovd, Kristine B; Paus, Tomáš; Fjell, Anders Martin; Huster, Rene & Tamnes, Christian Krog (2019). Error processing in the adolescent brain: Age-related differences in electrophysiology, behavioral adaptation, and brain morphology. Developmental Cognitive Neuroscience.  ISSN 1878-9293.  38 . doi: 10.1016/j.dcn.2019.100665 Fulltekst i vitenarkiv.
• Amlien, Inge Kasbohm; Sneve, Markus Handal; Vidal-Piñeiro, Didac; Walhovd, Kristine B & Fjell, Anders Martin (2018). The lifespan trajectory of the encoding-retrieval flip: A multimodal examination of medial parietal cortex contributions to episodic memory. Journal of Neuroscience.  ISSN 0270-6474.  38(40), s 8666- 8679 . doi: 10.1523/JNEUROSCI.1702-17.2018 Fulltekst i vitenarkiv.
• Bråthen, Anne Cecilie Sjøli; de Lange, Ann-Marie Glasø; Rohani, Darius; Sneve, Markus Handal; Fjell, Anders Martin & Walhovd, Kristine B (2018). Multimodal cortical and hippocampal prediction of episodic‐memory plasticity in young and older adults. Human Brain Mapping.  ISSN 1065-9471.  39(11), s 4480- 4492 . doi: 10.1002/hbm.24287 Fulltekst i vitenarkiv.
• de Lange, Ann-Marie Glasø; Bråthen, Anne Cecilie Sjøli; Rohani, Darius; Fjell, Anders Martin & Walhovd, Kristine B (2018). The temporal dynamics of brain plasticity in aging. Cerebral Cortex.  ISSN 1047-3211.  28(5), s 1857- 1865 . doi: 10.1093/cercor/bhy003 Fulltekst i vitenarkiv.
• Ferschmann, Lia; Fjell, Anders Martin; Vollrath, Margarete E.; Grydeland, Håkon; Walhovd, Kristine B & Tamnes, Christian Krog (2018). Personality Traits Are Associated With Cortical Development Across Adolescence: A Longitudinal Structural MRI Study. Child Development.  ISSN 0009-3920.  89(3), s 811- 822 . doi: 10.1111/cdev.13016 Fulltekst i vitenarkiv.
• Krogsrud, Stine Kleppe; Fjell, Anders Martin; Tamnes, Christian Krog; Grydeland, Håkon; Due-Tønnessen, Paulina; Bjørnerud, Atle; Sampaio-Baptista, Cassandra; Andersson, Jesper; Johansen-Berg, Heidi & Walhovd, Kristine B (2018). Development of white matter microstructure in relation to verbal and visuospatial working memory - A longitudinal study. PLOS ONE.  ISSN 1932-6203.  13:e0195540(4), s 1- 22 . doi: 10.1371/journal.pone.0195540 Fulltekst i vitenarkiv.
• Langnes, Espen; Vidal-Piñeiro, Didac; Sneve, Markus Handal; Amlien, Inge Kasbohm; Walhovd, Kristine B & Fjell, Anders Martin (2018). Development and decline of the hippocampal long-axis specialization and differentiation during encoding and retrieval of episodic memories. Cerebral Cortex.  ISSN 1047-3211.  s 1- 17 . doi: 10.1093/cercor/bhy209 Fulltekst i vitenarkiv.
• Nyberg, Claudia Kim; Nordvik, Jan Egil; Becker, Frank; Rohani, Darius; Sederevicius, Donatas; Fjell, Anders Martin & Walhovd, Kristine B (2018). A longitudinal study of computerized cognitive training in stroke patients - effects on cognitive function and white matter. Topics in Stroke Rehabilitation.  ISSN 1074-9357.  25(4), s 241- 247 . doi: 10.1080/10749357.2018.1443570 Fulltekst i vitenarkiv.
• Nygaard, Egil; Slinning, Kari; Moe, Vibeke; Due-Tønnessen, Paulina; Fjell, Anders Martin & Walhovd, Kristine B (2018). Neuroanatomical characteristics of youths with prenatal opioid and poly-drug exposure. Neurotoxicology and Teratology.  ISSN 0892-0362.  68, s 13- 26 . doi: 10.1016/j.ntt.2018.04.004 Fulltekst i vitenarkiv.
• Skumlien, Martine; Sederevicius, Donatas; Fjell, Anders Martin; Walhovd, Kristine B & Westerhausen, Rene (2018). Parallel but independent reduction of emotional awareness and corpus callosum connectivity in older age. PLOS ONE.  ISSN 1932-6203.  13(12), s 1- 18 . doi: 10.1371/journal.pone.0209915 Fulltekst i vitenarkiv.
• Tamnes, Christian Krog; Øverbye, Knut; Ferschmann, Lia; Fjell, Anders Martin; Walhovd, Kristine B; Blakemore, Sarah-Jayne & Dumontheil, Iroise (2018). Social perspective taking is associated with self-reported prosocial behavior and regional cortical thickness across adolescence. Developmental Psychology.  ISSN 0012-1649.  54(9), s 1745- 1757 . doi: 10.1037/dev0000541 Fulltekst i vitenarkiv.
• Walhovd, Kristine B; Fjell, Anders Martin; Westerhausen, René; Nyberg, L; Ebmeier, K P; Lindenberger, U; Bartres-Faz, D; Baare, W F C; Siebner, H R; Henson, R; Drevon, C A; Knudsen, Gun Peggy S.; Ljøsne, Isabelle Budin; Penninx, B W J H; Ghisletta, P; Røgeberg, Ole; Tyler, L & Bertram, L (2018). Healthy minds 0-100 years: Optimising the use of European brain imaging cohorts ("Lifebrain"). European psychiatry.  ISSN 0924-9338.  50, s 47- 56 . doi: 10.1016/j.eurpsy.2017.12.006 Fulltekst i vitenarkiv.
• Øverbye, Knut; Huster, Rene; Walhovd, Kristine B; Fjell, Anders Martin & Tamnes, Christian Krog (2018). Development of the P300 from childhood to adulthood: a multimodal EEG and MRI study. Brain Structure and Function.  ISSN 1863-2653.  223, s 4337- 4349 . doi: 10.1007/s00429-018-1755-5
• de Lange, Ann-Marie Glasø; Bråthen, Anne Cecilie Sjøli; Rohani, Darius; Grydeland, Håkon; Fjell, Anders Martin & Walhovd, Kristine B (2017). The Effects of Memory Training on Behavioral and Microstructural Plasticity in Young and Older Adults. Human Brain Mapping.  ISSN 1065-9471.  38(11), s 5666- 5680 . doi: 10.1002/hbm.23756 Fulltekst i vitenarkiv.
• Fjell, Anders Martin; Idland, Ane-Victoria; Sala Llonch, Roser; Watne, Leiv Otto; Borza, Tom; Brækhus, Anne; Lona, Tarjei; Zetterberg, Henrik; Blennow, Kaj; Wyller, Torgeir Bruun & Walhovd, Kristine B (2017). Neuroinflammation and tau interact with amyloid in predicting sleep problems in aging independently of atrophy. Cerebral Cortex.  ISSN 1047-3211.  28(8), s 2775- 2785 . doi: 10.1093/cercor/bhx157
• Fjell, Anders Martin; Sneve, Markus Handal; Grydeland, Håkon; Storsve, Andreas Berg; Amlien, Inge Kasbohm; Yendiki, Anastasia & Walhovd, Kristine B (2017). Relationship between structural and functional connectivity change across the lifespan – a longitudinal investigation. Human Brain Mapping.  ISSN 1065-9471.  38(1), s 561- 573 . doi: 10.1002/hbm.23403 Fulltekst i vitenarkiv.
• Idland, Ane-Victoria; Roser, Sala-Llonch; Borza, Tom; Watne, Leiv Otto; Wyller, Torgeir Bruun; Brækhus, Anne; Zetterberg, Henrik; Blennow, Kaj; Walhovd, Kristine B & Fjell, Anders Martin (2017). CSF neurofilament light levels predict hippocampal atrophy in cognitively healthy older adults. Neurobiology of Aging.  ISSN 0197-4580.  49, s 138- 144 . doi: 10.1016/j.neurobiolaging.2016.09.012 Fulltekst i vitenarkiv.
• Sala Llonch, Roser; Idland, Ane-Victoria; Borza, Tom; Watne, Leiv Otto; Wyller, Torgeir Bruun; Brækhus, Anne; Zetterberg, Henrik; Blennow, Kaj; Walhovd, Kristine B & Fjell, Anders Martin (2017). Inflammation, Amyloid, and Atrophy in The Aging Brain: Relationships with Longitudinal Changes in Cognition. Journal of Alzheimer's Disease.  ISSN 1387-2877.  58(3), s 829- 840 . doi: 10.3233/JAD-161146 Vis sammendrag

  Amyloid deposition occurs in aging, even in individuals free from cognitive symptoms, and is often interpreted as preclinical Alzheimer’s disease (AD) pathophysiology. YKL-40 is a marker of neuroinflammation, being increased in AD, and hypothesized to interact with amyloid-β (Aβ) in causing cognitive decline early in the cascade of AD pathophysiology. Whether and how Aβ and YKL-40 affect brain and cognitive changes in cognitively healthy older adults is still unknown. We studied 89 participants (mean age: 73.1 years) with cerebrospinal fluid samples at baseline, and both MRI and cognitive assessments from two time-points separated by two years. We tested how baseline levels of Aβ42 and YKL-40 correlated with changes in cortical thickness and cognition. Thickness change correlated with Aβ42 only in Aβ42+ participants (<600 pg/mL, n = 27) in the left motor and premotor cortices. Aβ42 was unrelated to cognitive change. Increased YKL-40 was associated with less preservation of scores on the animal naming test in the total sample (r = –0.28, p = 0.012) and less preservation of a score reflecting global cognitive function for Aβ42+ participants (r = –0.58, p = 0.004). Our results suggest a role for inflammation in brain atrophy and cognitive changes in cognitively normal older adults, which partly depended on Aβ accumulation.

• Sneve, Markus Handal; Grydeland, Håkon; Amlien, Inge Kasbohm; Langnes, Espen; Walhovd, Kristine B & Fjell, Anders Martin (2017). Decoupling of large-scale brain networks supports the consolidation of durable episodic memories. NeuroImage.  ISSN 1053-8119.  153, s 336- 345 . doi: 10.1016/j.neuroimage.2016.05.048 Fulltekst i vitenarkiv.
• Vidal-Piñeiro, Didac; Sneve, Markus Handal; Storsve, Andreas Berg; Roe, James Michael; Walhovd, Kristine B & Fjell, Anders Martin (2017). Neural correlates of durable memories across the adult lifespan: brain activity at encoding and retrieval. Neurobiology of Aging.  ISSN 0197-4580.  60, s 20- 33 . doi: 10.1016/j.neurobiolaging.2017.08.017 Fulltekst i vitenarkiv.
• Westerhausen, Rene; Friesen, Charline-Marie; Rohani, Darius; Krogsrud, Stine Kleppe; Tamnes, Christian Krog; Skranes, Jon Sverre; Håberg, Asta; Fjell, Anders Martin & Walhovd, Kristine B (2017). The corpus callosum as anatomical marker of intelligence? A critical examination in a large-scale developmental study. Brain Structure and Function.  ISSN 1863-2653.  223, s 285- 296 . doi: 10.1007/s00429-017-1493-0
• Almaas, Astrid; Tamnes, Christian Krog; Nakstad, Britt; Henriksen, Christine; Grydeland, Håkon; Walhovd, Kristine B; Fjell, Anders Martin; Iversen, Per Ole & Drevon, Christian A (2016). Diffusion tensor imaging and behavior in premature infants at 8 years of age, a randomized controlled trial with long-chain polyunsaturated fatty acids. Early Human Development.  ISSN 0378-3782.  95, s 41- 46 . doi: 10.1016/j.earlhumdev.2016.01.021
• Amlien, Inge; Fjell, Anders Martin; Tamnes, Christian Krog; Grydeland, Håkon; Krogsrud, Stine Kleppe; Chaplin, Tristan A.; Rosa, Marcello G.P. & Walhovd, Kristine B (2016). Organizing Principles of Human Cortical Development - Thickness and Area from 4 to 30 Years: Insights from Comparative Primate Neuroanatomy. Cerebral Cortex.  ISSN 1047-3211.  26(1), s 257- 267 . doi: 10.1093/cercor/bhu214
• Chepkoech, Joy-Loi; Walhovd, Kristine B; Grydeland, Håkon & Fjell, Anders Martin (2016). Effects of change in FreeSurfer version on classification accuracy of patients with Alzheimer's disease and mild cognitive impairment. Human Brain Mapping.  ISSN 1065-9471.  37(5), s 1831- 1841 . doi: 10.1002/hbm.23139
• de Lange, Ann-Marie Glasø; Bråthen, Anne Cecilie Sjøli; Grydeland, Håkon; Sexton, Claire; Johansen-Berg, Heidi; Andersson, Jesper L.R.; Rohani, Darius; Nyberg, Lars; Fjell, Anders Martin & Walhovd, Kristine B (2016). White-matter integrity as a marker for cognitive plasticity in aging. Neurobiology of Aging.  ISSN 0197-4580.  47, s 74- 82 . doi: 10.1016/j.neurobiolaging.2016.07.007
• Fjell, Anders Martin; Sneve, Markus Handal; Grydeland, Håkon; Storsve, Andreas Berg & Walhovd, Kristine B (2016). The Disconnected Brain and Executive Function Decline in Aging. Cerebral Cortex.  ISSN 1047-3211. . doi: 10.1093/cercor/bhw082 Fulltekst i vitenarkiv.
• Fjell, Anders Martin; Sneve, Markus Handal; Storsve, Andreas Berg; Grydeland, Håkon; Yendiki, Anastasia & Walhovd, Kristine B (2016). Brain Events Underlying Episodic Memory Changes in Aging: A Longitudinal Investigation of Structural and Functional Connectivity. Cerebral Cortex.  ISSN 1047-3211.  26(3), s 1272- 1286 . doi: 10.1093/cercor/bhv102 Fulltekst i vitenarkiv.
• Grydeland, Håkon; Westlye, Lars Tjelta; Walhovd, Kristine B & Fjell, Anders Martin (2016). Intracortical Posterior Cingulate Myelin Content Relates to Error Processing – Results From T1- and T2-weighted MRI Myelin Mapping and Electrophysiology in Healthy Adults. Cerebral Cortex.  ISSN 1047-3211.  26(6), s 2402- 2410 . doi: 10.1093/cercor/bhv065 Fulltekst i vitenarkiv.
• Krogsrud, Stine Kleppe; Fjell, Anders Martin; Tamnes, Christian Krog; Grydeland, Håkon; Ferschmann, Lia; Due-Tønnessen, Paulina; Bjørnerud, Atle; Sampaio-Baptista, Cassandra; Andersson, Jesper; Johansen-Berg, Heidi & Walhovd, Kristine B (2016). Changes in white matter microstructure in the developing brain - A longitudinal diffusion tensor imaging study of children from 4 to 11years of age. NeuroImage.  ISSN 1053-8119.  124, s 473- 486 . doi: 10.1016/j.neuroimage.2015.09.017
• Piñeiro, Didac Vidal; Walhovd, Kristine B; Storsve, Andreas Berg; Grydeland, Håkon; Rohani, Darius Adam & Fjell, Anders Martin (2016). Accelerated longitudinal gray/white matter contrast decline in aging in lightly myelinated cortical regions. Human Brain Mapping.  ISSN 1065-9471.  37(10), s 3669- 3684 . doi: 10.1002/hbm.23267 Fulltekst i vitenarkiv.
• Storsve, Andreas Berg; Fjell, Anders Martin; Yendiki, Anastasia & Walhovd, Kristine B (2016). Longitudinal changes in white matter tract integrity across the adult lifespan and its relation to cortical thinning. PLOS ONE.  ISSN 1932-6203.  11(6) . doi: 10.1371/journal.pone.0156770 Fulltekst i vitenarkiv.
• Walhovd, Kristine B; Fjell, Anders Martin; Giedd, J; Dale, AM & Brown, Timothy T. (2016). Through thick and thin: A need to reconcile contradictory results on trajectories in human cortical development. Cerebral Cortex.  ISSN 1047-3211. . doi: 10.1093/cercor/bhv301 Fulltekst i vitenarkiv.
• Walhovd, Kristine B; Krogsrud, Stine Kleppe; Amlien, Inge Kasbohm; Bartsch, Hauke; Bjørnerud, Atle; Due-Tønnessen, Paulina; Grydeland, Håkon; Hagler, D.; Håberg, Asta; Kremen, William S.; Ferschmann, Lia; Nyberg, Lars; Panizzon, Matthew S; Rohani, Darius; Skranes, Jon Sverre; Storsve, Andreas Berg; Sølsnes, Anne Elisabeth; Tamnes, Christian Krog; Thompson, Wesley K.; Reuter, Chase; Dale, Anders & Fjell, Anders Martin (2016). Neurodevelopmental origins of lifespan changes in brain and cognition. Proceedings of the National Academy of Sciences of the United States of America.  ISSN 0027-8424.  113(33), s 9357- 9362 . doi: 10.1073/pnas.1524259113 Fulltekst i vitenarkiv.
• Walhovd, Kristine B; Westerhausen, Rene; de Lange, Ann-Marie Glasø; Bråthen, Anne Cecilie Sjøli; Grydeland, Håkon; Engvig, Andreas & Fjell, Anders Martin (2016). Premises of plasticity - And the loneliness of the medial temporal lobe. NeuroImage.  ISSN 1053-8119.  131, s 48- 54 . doi: 10.1016/j.neuroimage.2015.10.060 Fulltekst i vitenarkiv.
• Westerhausen, Rene; Fjell, Anders Martin; Krogsrud, Stine Kleppe; Rohani, Darius Adam; Skranes, Jon Sverre; Håberg, Asta & Walhovd, Kristine B (2016). Selective increase in posterior corpus callosum thickness between the age of 4 and 11 years. NeuroImage.  ISSN 1053-8119.  139, s 17- 25 . doi: 10.1016/j.neuroimage.2016.06.008
• Almaas, Astrid; Tamnes, Christian Krog; Nakstad, Britt; Henriksen, Christine; Walhovd, Kristine B; Fjell, Anders Martin; Due-Tønnessen, Paulina; Drevon, Christian A & Iversen, Per Ole (2015). Long-chain polyunsaturated fatty acids and cognition in VLBW infants at 8 years: An RCT. Pediatrics.  ISSN 0031-4005.  135(6), s 972- 980 . doi: 10.1542/peds.2014-4094
• Fjell, Anders Martin; Amlien, Inge; Sneve, Markus Handal; Grydeland, Håkon; Tamnes, Christian Krog; Chaplin, Tristan; Rosa, Marcello & Walhovd, Kristine B (2015). The roots of Alzheimer's disease: Are high-expanding cortical areas preferentially targeted?. Cerebral Cortex.  ISSN 1047-3211.  25(9), s 2556- 2565 . doi: 10.1093/cercor/bhu055 Fulltekst i vitenarkiv.
• Fjell, Anders Martin; Grydeland, Håkon; Krogsrud, Stine Kleppe; Amlien, Inge Kasbohm; Rohani, Darius Adam; Ferschmann, Lia; Storsve, Andreas Berg; Tamnes, Christian Krog; Sala Llonch, Roser; Due-Tønnessen, Paulina; Bjørnerud, Atle; Sølsnes, Anne Elisabeth; Håberg, Asta; Skranes, Jon Sverre; Bartsch, Hauke; Chen, Chi-Hua; Thompson, Wesley K.; Panizzon, Matthew S.; Kremen, William S.; Dale, Anders M. & Walhovd, Kristine B (2015). Development and aging of cortical thickness correspond to genetic organization patterns. Proceedings of the National Academy of Sciences of the United States of America.  ISSN 0027-8424.  112(50), s 15462- 15467 . doi: 10.1073/pnas.1508831112 Fulltekst i vitenarkiv. Vis sammendrag

  There is a growing realization that early life influences have lasting impact on brain function and structure. Recent research has demon- strated that genetic relationships in adults can be used to parcellate the cortex into regions of maximal shared genetic influence, and a major hypothesis is that genetically progr ammed neurodevel opmental events cause a lasting impact on the organization of the cerebral cortex observable decades later. Here we tested how developmental and lifespan changes in cortical thickness fit the underlying genetic organi- zational principles of co rtical thickness in a longitudinal sample of 974 participants between 4.1 and 88.5 y of age with a total of 1,633 scans, including 773 scans from children below 12 y. Genetic clustering of cortical thickness was based on an independent dataset of 406 adult twins. Developmental and adult age- related changes in cortical thick- ness followed closely the genetic organization of the cerebral cortex, with change rates varying as a functi on of genetic similarity between regions. Cortical regions with overlapping genetic architecture showed correlated development al and adult age change trajectories and vice versa for regions with low genetic overlap. Thus, effects of genes on regional variations in cortical thickness in middle age can be traced to regional differences in neurodevelopmental change rates and extrap- olated to further adult aging-related cortical thinning. This finding suggests that genetic factors contribute to cortical changes through life and calls for a lifespan perspective i n research aimed at identifying the genetic and environmental determinants of cortical development and aging.

• Fjell, Anders Martin; Sneve, Markus Handal; Grydeland, Håkon; Storsve, Andreas Berg; de Lange, Ann-Marie Glasø; Amlien, Inge Kasbohm; Røgeberg, Ole & Walhovd, Kristine B (2015). Functional connectivity change across multiple cortical networks relates to episodic memory changes in aging. Neurobiology of Aging.  ISSN 0197-4580.  36(12), s 3255- 3268 . doi: 10.1016/j.neurobiolaging.2015.08.020 Fulltekst i vitenarkiv.
• Fjell, Anders Martin; Westlye, Lars Tjelta; Amlien, Inge; Tamnes, Christian Krog; Grydeland, Håkon; Engvig, Andreas; Espeseth, Thomas; Reinvang, Ivar; Lundervold, Astri; Lundervold, Arvid & Walhovd, Kristine B (2015). High-expanding cortical regions in human development and evolution are related to higher intellectual abilities. Cerebral Cortex.  ISSN 1047-3211.  25, s 26- 34 . doi: 10.1093/cercor/bht201 Fulltekst i vitenarkiv.
• Jack, Clifford R.; Barnes, Josephine; Bernstein, Matt A.; Borowski, Bret J.; Brewer, James; Clegg, Shona; Dale, Anders M.; Carmichael, Owen; Ching, Christopher; DeCarli, Charles; Desikan, Rahul S.; Fennema-Notestine, Christine; Fjell, Anders Martin; Fletcher, Evan; Fox, Nick C.; Gunter, Jeff; Gutman, Boris A.; Holland, Dominic; Hua, Xue; Insel, Philip; Kantarci, Kejal; Killiany, Ron J.; Krueger, Gunnar; Leung, Kelvin K.; Mackin, Scott; Maillard, Pauline; Malone, Ian B.; Mattsson, Niklas; McEvoy, Linda; Modat, Marc; Mueller, Susanne; Nosheny, Rachel; Ourselin, Sebastien; Schuff, Norbert; Senjem, Matthew L.; Simonson, Alix; Thompson, Paul M.; Rettmann, Dan; Vemuri, Prashanthi; Walhovd, Kristine B; Zhao, Yansong; Zuk, Samantha & Weiner, Michael (2015). Magnetic resonance imaging in Alzheimer's Disease Neuroimaging Initiative 2. Alzheimer's & Dementia.  ISSN 1552-5260.  11(7), s 740- 756 . doi: 10.1016/j.jalz.2015.05.002
• Kanellopoulos, Adriani; Andersson, Stein; Zeller, Bernward; Tamnes, Christian Krog; Fjell, Anders Martin; Walhovd, Kristine B; Westlye, Lars Tjelta; Fosså, Sophie Dorothea & Ruud, Ellen (2015). Neurocognitive Outcome in Very Long-Term Survivors of Childhood Acute Lymphoblastic Leukemia After Treatment with Chemotherapy Only. Pediatric Blood & Cancer.  ISSN 1545-5009.  63(1), s 133- 138 . doi: 10.1002/pbc.25690
• Nygaard, Gro Owren; Celius, Elisabeth Gulowsen; de Rodez Benavent, Sigrid Aune; Sowa, Piotr; Gustavsen, Marte Wendel; Fjell, Anders Martin; Landrø, Nils Inge; Walhovd, Kristine B & Harbo, Hanne Flinstad (2015). A longitudinal study of disability, cognition and gray matter atrophy in early multiple sclerosis patients according to evidence of disease activity. PLOS ONE.  ISSN 1932-6203.  10(8) . doi: 10.1371/journal.pone.0135974 Fulltekst i vitenarkiv.
• Nygaard, Gro Owren; Walhovd, Kristine B; Sowa, Piotr; Chepkoech, Joy-Loi; Bjørnerud, Atle; Due-Tønnessen, Paulina; Landrø, Nils Inge; Damangir, Soheil; Spulber, Gabriela; Storsve, Andreas Berg; Kristiansen Beyer, Mona; Fjell, Anders Martin; Celius, Elisabeth Gulowsen & Harbo, Hanne Flinstad (2015). Cortical thickness and surface area relate to specific symptoms in early relapsing−remitting multiple sclerosis. Multiple Sclerosis.  ISSN 1352-4585.  21(4), s 402- 414 . doi: 10.1177/1352458514543811
• Sneve, Markus Handal; Grydeland, Håkon; Nyberg, Lars; Bowles, Ben; Amlien, Inge Kasbohm; Langnes, Espen; Walhovd, Kristine B & Fjell, Anders Martin (2015). Mechanisms underlying encoding of short-lived versus durable episodic memories. Journal of Neuroscience.  ISSN 0270-6474.  35(13), s 5202- 5212 . doi: 10.1523/JNEUROSCI.4434-14.2015 Fulltekst i vitenarkiv.
• Tamnes, Christian Krog; Zeller, Bernward; Amlien, Inge; Kanellopoulos, Adriani; Andersson, Stein; Due-Tønnessen, Paulina; Ruud, Ellen; Walhovd, Kristine B & Fjell, Anders Martin (2015). Cortical surface area and thickness in adult survivors of pediatric acute lymphoblastic leukemia. Pediatric Blood & Cancer.  ISSN 1545-5009.  62(6), s 1027- 1034 . doi: 10.1002/pbc.25386
• Walhovd, Kristine B; Bjørnebekk, Astrid; Haabrekke, Kristin Johanne; Siqveland, Torill; Slinning, Kari; Nygaard, Egil; Fjell, Anders Martin; Due-Tønnessen, Paulina; Bjørnerud, Atle & Moe, Vibeke (2015). Child Neuroanatomical, Neurocognitive, and Visual Acuity Outcomes With Maternal Opioid and Polysubstance Detoxification. Pediatric Neurology.  ISSN 0887-8994.  52(3), s 326- 332.e3 . doi: 10.1016/j.pediatrneurol.2014.11.008
• Walhovd, Kristine B; Tamnes, Christian Krog; Bjørnerud, Atle; Due-Tønnessen, Paulina; Holland, Dominic; Dale, Anders M. & Fjell, Anders Martin (2015). Maturation of Cortico-Subcortical Structural Networks - Segregation and Overlap of Medial Temporal and Fronto-Striatal Systems in Development. Cerebral Cortex.  ISSN 1047-3211.  25(7), s 1835- 1841 . doi: 10.1093/cercor/bht424
• Amlien, Inge & Fjell, Anders Martin (2014). Diffusion tensor imaging of white matter degeneration in Alzheimer's disease and mild cognitive impairment. Neuroscience.  ISSN 0306-4522.  276, s 206- 215 . doi: 10.1016/j.neuroscience.2014.02.017
• Bjørnebekk, Astrid; Siqveland, Torill; Haabrekke, Kristin Johanne; Moe, Vibeke; Slinning, Kari; Fjell, Anders Martin & Walhovd, Kristine B (2014). Development of children born to mothers with mental health problems: subcortical volumes and cognitive performance at 4½ years. European Child and Adolescent Psychiatry.  ISSN 1018-8827.  24(1), s 115- 118 . doi: 10.1007/s00787-014-0625-9
• Douaud, Gwenaëlle; Groves, Adrian; Tamnes, Christian Krog; Westlye, Lars Tjelta; Duff, Eugene; Engvig, Andreas; Walhovd, Kristine B; James, Anthony; Gass, Achim; Monsch, Andreas U.; Matthews, Paul M.; Fjell, Anders Martin; Smith, Stephen & Johansen-Berg, Heidi (2014). A common brain network links development, aging, and vulnerability to disease. Proceedings of the National Academy of Sciences of the United States of America.  ISSN 0027-8424.  111(49), s 17648- 17653 . doi: 10.1073/pnas.1410378111
• Engvig, Andreas; Fjell, Anders Martin; Westlye, Lars Tjelta; Skaane, Nina Voss; Dale, Anders M.; Holland, Dominic; Due-Tønnessen, Paulina; Sundset, Øyvind & Walhovd, Kristine B (2014). Effects of Cognitive Training on Gray Matter Volumes in Memory Clinic Patients with Subjective Memory Impairment. Journal of Alzheimer's Disease.  ISSN 1387-2877. . doi: 10.3233/JAD-131889 Fulltekst i vitenarkiv.
• Fjell, Anders Martin; McEvoy, Linda; Holland, Dominic; Dale, Anders & Walhovd, Kristine B (2014). What is normal in normal aging? Effects of aging, amyloid and Alzheimer's disease on the cerebral cortex and the hippocampus. Progress in Neurobiology.  ISSN 0301-0082.  117, s 20- 40 . doi: 10.1016/j.pneurobio.2014.02.004 Fulltekst i vitenarkiv.
• Fjell, Anders Martin; Westlye, Lars Tjelta; Grydeland, Håkon; Amlien, Inge; Espeseth, Thomas; Reinvang, Ivar; Raz, Naftali; Dale, Anders & Walhovd, Kristine B (2014). Accelerating cortical thinning: Unique to dementia or universal in aging?. Cerebral Cortex.  ISSN 1047-3211.  24(4), s 919- 934 . doi: 10.1093/cercor/bhs379
• Krogsrud, Stine Kleppe; Tamnes, Christian Krog; Fjell, Anders Martin; Amlien, Inge; Grydeland, Håkon; Sulutvedt, Unni; Due-Tønnessen, Paulina; Bjørnerud, Atle; Sølsnes, Anne Elisabeth; Håberg, Asta; Skranes, Jon Sverre & Walhovd, Kristine B (2014). Development of hippocampal subfield volumes from 4 to 22 years. Human Brain Mapping.  ISSN 1065-9471.  35(11), s 5646- 5657 . doi: 10.1002/hbm.22576 Fulltekst i vitenarkiv.
• Nordvik, Jan Egil; Walle, Kjersti Mæhlum; Nyberg, Claudia; Fjell, Anders Martin; Walhovd, Kristine B; Westlye, Lars Tjelta & Tornås, Sveinung (2014). Bridging the gap between clinical neuroscience and cognitive rehabilitation: The role of cognitive training, models of neuroplasticity and advanced neuroimaging in future brain injury rehabilitation. NeuroRehabilitation (Reading, MA).  ISSN 1053-8135.  34(1), s 81- 85 . doi: 10.3233/NRE-131017
• Sexton, Claire E; Storsve, Andreas Berg; Walhovd, Kristine B; Johansen-Berg, Heidi & Fjell, Anders Martin (2014). Poor Sleep Quality is Associated With Increased Cortical Atrophy in Community-Dwelling Adults. Neurology.  ISSN 0028-3878.  83(11), s 967- 973 . doi: 10.1212/WNL.0000000000000774
• Sexton, Claire E; Walhovd, Kristine B; Storsve, Andreas Berg; Tamnes, Christian Krog; Westlye, Lars Tjelta; Johansen-Berg, Heidi & Fjell, Anders Martin (2014). Accelerated changes in white matter microstructure during aging: A longitudinal diffusion tensor imaging study. Journal of Neuroscience.  ISSN 0270-6474.  34(46), s 15425- 15436 . doi: 10.1523/JNEUROSCI.0203-14.2014
• Storsve, Andreas Berg; Fjell, Anders Martin; Tamnes, Christian Krog; Westlye, Lars Tjelta; Øverbye, Knut; Aasland, Hilde Wiede & Walhovd, Kristine B (2014). Differential longitudinal changes in cortical thickness, surface area and volume across the adult lifespan: Regions of accelerating and decelerating change. Journal of Neuroscience.  ISSN 0270-6474.  34(25), s 8488- 8498 . doi: 10.1523/JNEUROSCI.0391-14.2014 Fulltekst i vitenarkiv.
• Strømmen, Kenneth; Blakstad, Elin Wahl; Moltu, Sissel; Almaas, Astrid; Westerberg, Ane Cecilie; Amlien, Inge; Rønnestad, Arild Erlend; Nakstad, Britt; Drevon, Christian A; Bjørnerud, Atle; Courivaud, Fredric A A; Hol, Per Kristian; Veierød, Marit Bragelien; Fjell, Anders Martin; Walhovd, Kristine B & Iversen, Per Ole (2014). Enhanced Nutrient Supply to Very Low Birth Weight Infants is Associated with Improved White Matter Maturation and Head Growth. Neonatology.  ISSN 1661-7800.  107(1), s 68- 75 . doi: 10.1159/000368181
• Tamnes, Christian Krog; Walhovd, Kristine B; Engvig, Andreas; Grydeland, Håkon; Krogsrud, Stine Kleppe; Østby, Ylva; Holland, Dominic; Dale, Anders & Fjell, Anders Martin (2014). Regional hippocampal volumes and development predict learning and memory. Developmental Neuroscience.  ISSN 0378-5866.  36(3-4), s 161- 174 . doi: 10.1159/000362445 Fulltekst i vitenarkiv.
• Walhovd, Kristine B; Fjell, Anders Martin & Espeseth, Thomas (2014). Cognitive decline and brain pathology in aging - need for a dimensional, lifespan and systems vulnerability view. Scandinavian Journal of Psychology.  ISSN 0036-5564.  55(3), s 244- 254 . doi: 10.1111/sjop.12120 Fulltekst i vitenarkiv.
• Walhovd, Kristine B; Storsve, Andreas Berg; Westlye, Lars Tjelta; Drevon, Christian A & Fjell, Anders Martin (2014). Blood markers of fatty acids and vitamin D, cardiovascular measures, body mass index, and physical activity relate to longitudinal cortical thinning in normal aging. Neurobiology of Aging.  ISSN 0197-4580.  35(5), s 1055- 1064 . doi: 10.1016/j.neurobiolaging.2013.11.011
• Walhovd, Kristine B; Tamnes, Christian Krog & Fjell, Anders Martin (2014). Brain structural maturation and the foundations of cognitive behavioral development. Current Opinion in Neurology.  ISSN 1350-7540.  27(2), s 176- 184 . doi: 10.1097/WCO.0000000000000074 Fulltekst i vitenarkiv.
• Amlien, Inge; Fjell, Anders Martin; Walhovd, Kristine B; Selnes, Per; Stenset, Vidar; Grambaite, Ramune; Bjørnerud, Atle; Due-Tønnessen, Paulina; Skinningsrud, Anders; Gjerstad, Leif; Reinvang, Ivar & Fladby, Tormod (2013). Mild cognitive impairment: cerebrospinal fluid tau biomarker pathologic levels and longitudinal changes in white matter integrity. Radiology.  ISSN 0033-8419.  266(1), s 295- 303 . doi: 10.1148/radiol.12120319
• Bjørnebekk, Astrid; Fjell, Anders Martin; Walhovd, Kristine B; Grydeland, Håkon; Torgersen, Svenn & Westlye, Lars Tjelta (2013). Neuronal correlates of the five factor model (FFM) of human personality: Multimodal imaging in a large healthy sample. NeuroImage.  ISSN 1053-8119.  65, s 194- 208 . doi: 10.1016/j.neuroimage.2012.10.009 Vis sammendrag

  Advances in neuroimaging techniques have recently provided glimpse into the neurobiology of complex traits of human personality. Whereas some intriguing findings have connected aspects of personality to variations in brain morphology, the relations are complex and our current understanding is incomplete. Therefore, we aimed to provide a comprehensive investigation of brain–personality relations using a multimodal neuroimaging approach in a large sample comprising 265 healthy individuals. The NEO Personality Inventory was used to provide measures of core aspects of human personality, and imaging phenotypes included measures of total and regional brain volumes, regional cortical thickness and arealization, and diffusion tensor imaging indices of white matter (WM) microstructure. Neuroticism was the trait most clearly linked to brain structure. Higher neuroticism including facets reflecting anxiety, depression and vulnerability to stress was associated with smaller total brain volume, widespread decrease in WM microstructure, and smaller frontotemporal surface area. Higher scores on extraversion were associated with thinner inferior frontal gyrus, and conscientiousness was negatively associated with arealization of the temporoparietal junction. No reliable associations between brain structure and agreeableness and openness, respectively, were found. The results provide novel evidence of the associations between brain structure and variations in human personality, and corroborate previous findings of a consistent neuroanatomical basis of negative emotionality.

• Chen, Xue; Errangi, Barghav; Li, Lonchuan; Glasser, Matthew F; Westlye, Lars Tjelta; Fjell, Anders Martin; Walhovd, Kristine B; Hu, Xiaoping; Herndon, James G.; Preuss, Todd M. & Rilling, James K. (2013). Brain aging in humans, chimpanzees (Pan troglodytes), and rhesus macaques (Macaca mulatta): magnetic resonance imaging studies of macro- and microstructural changes. Neurobiology of Aging.  ISSN 0197-4580.  34(10), s 2248- 2260 . doi: 10.1016/j.neurobiolaging.2013.03.028
• Fjell, Anders Martin; McEvoy, Linda K.; Holland, Dominic; Dale, Anders M. & Walhovd, Kristine B (2013). Brain Changes in Older Adults at Very Low Risk for Alzheimer's Disease. Journal of Neuroscience.  ISSN 0270-6474.  33(19), s 8237- U511 . doi: 10.1523/JNEUROSCI.5506-12.2013
• Fjell, Anders Martin; Westlye, Lars Tjelta; Grydeland, Håkon; Amlien, Inge; Espeseth, Thomas; Reinvang, Ivar; Raz, Naftali; Holland, Dominic; Dale, Anders & Walhovd, Kristine B (2013). Critical ages in the life course of the adult brain: nonlinear subcortical aging. Neurobiology of Aging.  ISSN 0197-4580.  34(10), s 2239- 2247 . doi: 10.1016/j.neurobiolaging.2013.04.006 Fulltekst i vitenarkiv.
• Grydeland, Håkon; Walhovd, Kristine B; Tamnes, Christian Krog; Westlye, Lars Tjelta & Fjell, Anders Martin (2013). Intracortical Myelin Links with Performance Variability across the Human Lifespan: Results from T1-and T2-Weighted MRI Myelin Mapping and Diffusion Tensor Imaging. Journal of Neuroscience.  ISSN 0270-6474.  33(47), s 18618- 18630 . doi: 10.1523/JNEUROSCI.2811-13.2013 Fulltekst i vitenarkiv.
• Grydeland, Håkon; Westlye, Lars Tjelta; Walhovd, Kristine B & Fjell, Anders Martin (2013). Improved Prediction of Alzheimer's Disease with Longitudinal White Matter/Gray Matter Contrast Changes. Human Brain Mapping.  ISSN 1065-9471.  34(11), s 2775- 2785 . doi: 10.1002/hbm.22103
• Hogstrom, Larson; Westlye, Lars Tjelta; Walhovd, Kristine B & Fjell, Anders Martin (2013). The structure of the cerebral cortex across adult life: age-related patterns of surface area, thickness and gyrification. Cerebral Cortex.  ISSN 1047-3211.  23(11), s 2521- 2530 . doi: 10.1093/cercor/bhs231
• Tamnes, Christian Krog; Walhovd, Kristine B; Dale, Anders M.; Østby, Ylva; Grydeland, Håkon; Richardson, George; Westlye, Lars Tjelta; Roddey, J Cooper; Hagler, Donald J.; Due-Tønnessen, Paulina; Holland, Dominic; Fjell, Anders Martin & Database, ADNI (2013). Brain development and aging: Overlapping and unique patterns of change. NeuroImage.  ISSN 1053-8119.  68, s 63- 74 . doi: 10.1016/j.neuroimage.2012.11.039
• Tamnes, Christian Krog; Walhovd, Kristine B; Grydeland, Håkon; Holland, Dominic; Østby, Ylva; Dale, Anders M. & Fjell, Anders Martin (2013). Longitudinal Working Memory Development Is Related to Structural Maturation of Frontal and Parietal Cortices. Journal of Cognitive Neuroscience.  ISSN 0898-929X.  25(10), s 1611- 1623 . doi: 10.1162/jocn_a_00434 Fulltekst i vitenarkiv.
• Tamnes, Christian Krog; Walhovd, Kristine B; Torstveit, Mari; Sells, Victoria Torp & Fjell, Anders Martin (2013). Performance monitoring in children and adolescents: A review of developmental changes in the error-related negativity and brain maturation. Developmental Cognitive Neuroscience.  ISSN 1878-9293.  6, s 1- 13 . doi: 10.1016/j.dcn.2013.05.001 Fulltekst i vitenarkiv.
• Zeller, Bernward; Tamnes, Christian Krog; Kanellopoulos, Adriani; Amlien, Inge; Andersson, Stein; Due-Tønnessen, Paulina; Fjell, Anders Martin; Walhovd, Kristine B; Westlye, Lars Tjelta & Ruud, Ellen (2013). Reduced Neuroanatomic Volumes in Long-Term Survivors of Childhood Acute Lymphoblastic Leukemia. Journal of Clinical Oncology.  ISSN 0732-183X.  31, s 2078- 2085 . doi: 10.1200/JCO.2012.47.4031

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• Tamnes, Christian Krog; Krogsrud, Stine Kleppe; Fjell, Anders Martin & Walhovd, Kristine B (2015). Regional development of hippocampal subfield volumes and its associations with cognition and memory.
• Zeller, Bernward; Tamnes, Christian Krog; Kanellopoulos, Adriani; Amlien, Inge Kasbohm; Andersson, Stein; Due-Tønnessen, Paulina; Fjell, Anders Martin; Walhovd, Kristine B; Westlye, Lars Tjelta & Ruud, Ellen (2014). Response to A.A.M. van der Veldt et al. Journal of Clinical Oncology.  ISSN 0732-183X.  32(8), s 852- 853 . doi: 10.1200/JCO.2013.52.5725
• Engvig, Andreas; Fjell, Anders Martin; Westlye, Lars Tjelta; Skaane, Nina Voss & Walhovd, Kristine B (2013). Structural Brain Imaging Correlates of Memory Training in Middle and Old Age. Journal of Psychophysiology.  ISSN 0269-8803.  27, s 18- 18
• Storsve, Andreas Berg; Walhovd, Kristine B; Sneve, Markus Handal; Tamnes, Christian Krog; Krogsrud, Stine Kleppe & Fjell, Anders Martin (2013). Hukommelse gjennom livet - Nevrovitenskapelige perspektiver.

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