Lars Tjelta Westlye

Academic interests
I am a professor at the Department of Psychology, University of Oslo and Core Researcher and group leader at the Norwegian Center for Mental Disorders Research (NORMENT), Oslo University Hospital/University of Oslo.
Identifying mechanisms of disease is of vital importance to increase patient care and develop safe and effective treatment approaches. The heterogeneity and complexity of mental illnesses and other disorders of brain biology can only be fully appreciated by employing a cross-disciplinary and translational effort, preferably combined with a lifespan perspective.
Advanced neuroimaging techniques including MRI have revolutionized the understanding of the structural and functional makeup of the human brain. Structural and functional brain features are highly heritable, and our current research aims at characterizing the cognitive, brain and genetic mechanisms of severe neuropsychiatric disorders, in particular schizophrenia and bipolar spectrum disorders. In addition, in order to address questions pertaining to the clinical sensitivity and specificity of our results, we are aiming to compare and validate our findings across a range of brain disorders through a close collaboration with several clinical research groups. In addition, using brain network modeling approaches we are approaching the cognitive neuroscience of attention and memory functions, and questions related to the potential and mechanisms of neuroplasticity, both in clinical and non-clinical populations.
My research group utilizes various advanced MRI neuroimaging data and analysis approaches, with a particular emphasis on measures of structural (diffusion tensor imaging, DTI) and functional connectivity (functional magnetic resonance imaging, fMRI), and its integration using multimodal analysis approaches. In particular, by applying machine learning algorithms, we are investigating the clinical and cognitive sensitivity and specificity of various brain network-modeling approaches, including principles from graph theory.
In addition to the extended inter-disciplinary network of researchers at NORMENT and other clinical research groups at Oslo University Hospital, we are working closely with world-class international research groups, including the FMRIB Centre, Oxford University, and MMIL, UCSD.
Students interested in pursuing a cand psychol, MA or PhD within any of these areas of research are encouraged to contact me.
Higher education and employment history
Education
-
2011 PhD, University of Oslo
-
2007 Cand. Psychol. (professionally oriented degree in psychology), University of Oslo, accredited psychologist 2008
Employment history
- 2011 - 2012 Postdoctoral research fellow, Department of Psychology, University of Oslo
-
2011 Visiting Researcher, Multimodal Imaging Laboratory (MMIL), University of California San Diego, USA
-
2011 - Postdoctoral Research Fellow (research council of Norway), Center for the Study of Human Cognition, University of Oslo
-
2010 - 2011 Visiting Researcher, Oxford Centre for functional MRI of the Brain (FMRIB), University of Oxford, UK
-
2008 - 2011 PhD Research Fellow (The Research Council of Norway), Center for the Study of Human Cognition, Institute of Psychology, University of Oslo
-
2006 - 2007 Student Research Fellow (part time) (The Research Council of Norway), Department of Psychology, University of Oslo
-
2005 Student Research Fellow (full time) (The Research Council of Norway), Department of Psychology, University of Oslo
Publications
-
van der Meer, Dennis; Shadrin, Alexey; O'Connell, Kevin; Bettella, Francesco; Djurovic, Srdjan & Wolfers, Thomas [Show all 17 contributors for this article] (2022). Boosting Schizophrenia Genetics by Utilizing Genetic Overlap With Brain Morphology. Biological Psychiatry. ISSN 0006-3223. doi: 10.1016/j.biopsych.2021.12.007.
-
Rutherford, Saige; Fraza, Charlotte; Dinga, Richard; Kia, Seyed Mostafa; Wolfers, Thomas & Zabihi, Mariam [Show all 32 contributors for this article] (2022). Charting brain growth and aging at high spatial precision. eLIFE. ISSN 2050-084X. 11. doi: 10.7554/ELIFE.72904.
-
Scarth, Morgan; Havnes, Ingrid Amalia; Jørstad, Marie Lindvik; McVeigh, Jim; Van Hout, Marie Claire & Westlye, Lars Tjelta [Show all 8 contributors for this article] (2022). Severity of anabolic steroid dependence, executive function, and personality traits in substance use disorder patients in Norway. Drug and Alcohol Dependence. ISSN 0376-8716. 231. doi: 10.1016/j.drugalcdep.2022.109275.
-
Kjelkenes, Rikka; Wolfers, Thomas; Alnæs, Dag; van der Meer, Dennis; Pedersen, Mads Lund & Dahl, Andreas [Show all 12 contributors for this article] (2022). Mapping Normative Trajectories of Cognitive Function and Its Relation to Psychopathology Symptoms and Genetic Risk in Youth. biological psychiatry: global open science. ISSN 2667-1743. doi: 10.1016/j.bpsgos.2022.01.007.
-
Brouwer, Rachel M.; Klein, Marieke; Grasby, Katrina L.; Schnack, Hugo G.; Jahanshad, Neda & Teeuw, Jalmar [Show all 200 contributors for this article] (2022). Genetic variants associated with longitudinal changes in brain structure across the lifespan. Nature Neuroscience. ISSN 1097-6256. 25(4), p. 421–432. doi: 10.1038/s41593-022-01042-4.
-
Beck, Dani; de Lange, Ann-Marie Glasø; Alnæs, Dag; Maximov, Ivan; Pedersen, Mads Lund & Leinhard, Olof Dahlqvist [Show all 20 contributors for this article] (2022). Adipose tissue distribution from body MRI is associated with cross-sectional and longitudinal brain age in adults. NeuroImage: Clinical. ISSN 2213-1582. 33. doi: 10.1016/j.nicl.2022.102949.
-
Leonardsen, Esten Høyland; Peng, Han; Kaufmann, Tobias; Agartz, Ingrid; Andreassen, Ole A. & Celius, Elisabeth Gulowsen [Show all 19 contributors for this article] (2022). Deep neural networks learn general and clinically relevant representations of the ageing brain. NeuroImage. ISSN 1053-8119. doi: 10.1016/j.neuroimage.2022.119210.
-
Subramaniapillai, Sivaniya; Suri, Sana; Barth, Claudia; Maximov, Ivan; Voldsbekk, Irene & van der Meer, Dennis [Show all 13 contributors for this article] (2022). Sex- and age-specific associations between cardiometabolic risk and white matter brain age in the UK Biobank cohort. Human Brain Mapping. ISSN 1065-9471. doi: 10.1002/hbm.25882.
-
Voldsbekk, Irene; Bjørnerud, Atle; Groote, Inge Rasmus; Zak, Nathalia; Roelfs, Daniël & Maximov, Ivan [Show all 18 contributors for this article] (2022). Evidence for widespread alterations in cortical microstructure after 32 h of sleep deprivation. Translational Psychiatry. ISSN 2158-3188. doi: 10.1038/s41398-022-01909-x.
-
Rokicki, Jaroslav; Kaufmann, Tobias; de Lange, Ann-Marie Glasø; van der Meer, Dennis; Bahrami, Shahram & Sartorius, Alina [Show all 14 contributors for this article] (2022). Oxytocin receptor expression patterns in the human brain across development. Neuropsychopharmacology. ISSN 0893-133X. doi: 10.1038/s41386-022-01305-5.
-
de Lange, Ann-Marie Glasø; Anatürk, Melis; Rokicki, Jaroslav; Han, Laura K.M.; Franke, Katja & Alnæs, Dag [Show all 12 contributors for this article] (2022). Mind the gap: Performance metric evaluation in brain-age prediction. Human Brain Mapping. ISSN 1065-9471. doi: 10.1002/hbm.25837.
-
Frangou, Sophia; Agartz, Ingrid; Alnæs, Dag; Andreassen, Ole; Doan, Nhat Trung & Dørum, Erlend S. [Show all 13 contributors for this article] (2022). Cortical thickness across the lifespan: Data from 17,075 healthy individuals aged 3-90 years. Human Brain Mapping. ISSN 1065-9471. 43(1), p. 431–451. doi: 10.1002/hbm.25364.
-
Dima, Danai; Agartz, Ingrid; Alnæs, Dag; Andreassen, Ole; Doan, Nhat Trung & Dørum, Erlend Solberg [Show all 12 contributors for this article] (2022). Subcortical volumes across the lifespan: Data from 18,605 healthy individuals aged 3–90 years. Human Brain Mapping. ISSN 1065-9471. 43(1). doi: 10.1002/hbm.25320.
-
Liew, Sook-Lei; Zavaliangos-Petropulu, Artemis; Schweighofer, Nicolas; Jahanshad, Neda; Lang, Catherine E. & Lohse, Keith R. [Show all 52 contributors for this article] (2021). Smaller spared subcortical nuclei are associated with worse post-stroke sensorimotor outcomes in 28 cohorts worldwide . Brain Communications. ISSN 2632-1297. 3(4). doi: 10.1093/braincomms/fcab254.
-
Hui, Steve C.N.; Mikkelsen, Mark; Zöllner, Helge J.; Ahluwalia, Vishwadeep; Alcauter, Sarael & Baltusis, Laima [Show all 51 contributors for this article] (2021). Frequency drift in MR spectroscopy at 3T. NeuroImage. ISSN 1053-8119. 241. doi: 10.1016/j.neuroimage.2021.118430.
-
Winterton, Adriano; Bettella, Francesco; de Lange, Ann-Marie Glasø; Haram, Marit; Steen, Nils Eiel & Westlye, Lars Tjelta [Show all 8 contributors for this article] (2021). Oxytocin-pathway polygenic scores for severe mental disorders and metabolic phenotypes in the UK Biobank. Translational Psychiatry. ISSN 2158-3188. doi: 10.1038/s41398-021-01725-9. Full text in Research Archive
-
van der Meer, Dennis; Kaufmann, Tobias; Shadrin, Alexey; Makowski, Carolina; Frei, Oleksandr & Roelfs, Daniel [Show all 17 contributors for this article] (2021). The genetic architecture of human cortical folding. Science Advances. ISSN 2375-2548. 7(51), p. 1–9. doi: 10.1126/sciadv.abj9446. Full text in Research Archive
-
Lund, Martina Jonette; Alnæs, Dag; de Lange, Ann-Marie Glasø; Andreassen, Ole; Westlye, Lars Tjelta & Kaufmann, Tobias (2021). Brain age prediction using fMRI network coupling in youths and associations with psychiatric symptoms. NeuroImage: Clinical. ISSN 2213-1582. doi: 10.1016/j.nicl.2021.102921. Full text in Research Archive
-
Wortinger, Laura Anne ; Barth, Claudia; Nerland, Stener; Jørgensen, Kjetil Nordbø; Shadrin, Alexey & Szabo, Attila [Show all 11 contributors for this article] (2021). Association of Birth Asphyxia With Regional White Matter Abnormalities Among Patients With Schizophrenia and Bipolar Disorders. JAMA Network Open. ISSN 2574-3805. 4(12). doi: 10.1001/jamanetworkopen.2021.39759. Full text in Research Archive Show summary
-
Szabo, Attila; O'Connell, Kevin Sean; Ueland, Thor; Sheikh, Mashhood Ahmed; Agartz, Ingrid & Andreou, Dimitrios [Show all 31 contributors for this article] (2021). Increased circulating IL-18 levels in severe mental disorders indicate systemic inflammasome activation. Brain, Behavior, and Immunity. ISSN 0889-1591. 99, p. 299–306. doi: 10.1016/j.bbi.2021.10.017. Full text in Research Archive Show summary
-
Nerland, Stener; Jørgensen, Kjetil Nordbø; Nordhøy, Wibeke; Maximov, Ivan; Bugge, Robin Antony Birkeland & Westlye, Lars Tjelta [Show all 9 contributors for this article] (2021). Multisite reproducibility and test-retest reliability of the T1w/T2w-ratio: A comparison of processing methods. NeuroImage. ISSN 1053-8119. 245. doi: 10.1016/j.neuroimage.2021.118709. Full text in Research Archive
-
Hilland, Eva; Johannessen, Cecilie Haggag; Jonassen, Rune; Alnæs, Dag; Jørgensen, Kjetil Nordbø & Barth, Claudia [Show all 17 contributors for this article] (2021). Aberrant default mode connectivity in adolescents with early-onset psychosis: A resting state fMRI study. NeuroImage: Clinical. ISSN 2213-1582. 33. doi: 10.1016/j.nicl.2021.102881. Full text in Research Archive
-
Tahmasian, Masoud; Aleman, André; Andreassen, Ole; Arab, Zahra; Baillet, Marion & Benedetti, Francesco [Show all 77 contributors for this article] (2021). ENIGMA-Sleep: Challenges, opportunities, and the road map. Journal of Sleep Research. ISSN 0962-1105. 30(6), p. 1–20. doi: 10.1111/jsr.13347.
-
Abé, Christoph; Ching, Christopher R.K.; Liberg, Benny; Lebedev, Alexander V.; Agartz, Ingrid & Akudjedu, Theophilus N. [Show all 72 contributors for this article] (2021). Longitudinal Structural Brain Changes in Bipolar Disorder: A Multicenter Neuroimaging Study of 1232 Individuals by the ENIGMA Bipolar Disorder Working Group. Biological Psychiatry. ISSN 0006-3223. p. 1–11. doi: 10.1016/j.biopsych.2021.09.008. Full text in Research Archive
-
Valstad, Mathias; Roelfs, Daniel; Slapø, Nora Berz; Timpe, Clara Marie Fides; Rai, Ahsan & Matziorinis, Anna Maria [Show all 24 contributors for this article] (2021). Evidence for Reduced Long-Term Potentiation-Like Visual Cortical Plasticity in Schizophrenia and Bipolar Disorder. Schizophrenia Bulletin. ISSN 0586-7614. 47(6), p. 1751–1760. doi: 10.1093/schbul/sbab049. Full text in Research Archive
-
Andreou, Dimitrios; Steen, Nils Eiel; Jørgensen, Kjetil Nordbø; Smelror, Runar; Wedervang-Resell, Kirsten & Nerland, Stener [Show all 25 contributors for this article] (2021). Lower circulating neuron-specific enolase concentrations in adults and adolescents with severe mental illness. Psychological Medicine. ISSN 0033-2917. p. 1–10. doi: 10.1017/S0033291721003056. Full text in Research Archive
-
Shadrin, Alexey A.; Kaufmann, Tobias; van der Meer, Dennis; Palmer, Clare E.; Makowski, Carolina & Loughnan, Robert [Show all 22 contributors for this article] (2021). Vertex-wise multivariate genome-wide association study identifies 780 unique genetic loci associated with cortical morphology. NeuroImage. ISSN 1053-8119. 244, p. 1–8. doi: 10.1016/j.neuroimage.2021.118603. Full text in Research Archive
-
Tesli, Natalia; Rokicki, Jaroslav; Maximov, Ivan; Bell, Christina; Hjell, Gabriela & Gurholt, Tiril Pedersen [Show all 17 contributors for this article] (2021). White Matter Matters: Unraveling Violence in Psychosis and Psychopathy. Schizophrenia Bulletin Open. ISSN 2632-7899. 2(1). doi: 10.1093/schizbullopen/sgab026. Full text in Research Archive
-
Monereo-Sánchez, Jennifer; Luykx, Jurjen J.; Pinzón-Espinosa, Justo; Richard, Geneviève; Motazedi, Ehsan & Westlye, Lars Tjelta [Show all 8 contributors for this article] (2021). Diphtheria And Tetanus Vaccination History Is Associated With Lower Odds of COVID-19 Hospitalization. Frontiers in Immunology. ISSN 1664-3224. 12, p. 1–7. doi: 10.3389/fimmu.2021.749264. Full text in Research Archive
-
Beck, Dani; de Lange, Ann-Marie G.; Pedersen, Mads L.; Alnæs, Dag; Maximov, Ivan & Voldsbekk, Irene [Show all 18 contributors for this article] (2021). Cardiometabolic risk factors associated with brain age and accelerate brain ageing. Human Brain Mapping. ISSN 1065-9471. p. 1–21. doi: 10.1002/hbm.25680. Full text in Research Archive
-
Monereo-Sánchez, Jennifer; Schram, Miranda T.; Frei, Oleksandr; O'Connell, Kevin Sean; Shadrin, Alexey & Smeland, Olav Bjerkehagen [Show all 11 contributors for this article] (2021). Genetic Overlap Between Alzheimer’s Disease and Depression Mapped Onto the Brain. Frontiers in Neuroscience. ISSN 1662-4548. 15, p. 1–9. doi: 10.3389/fnins.2021.653130. Full text in Research Archive
-
Birkenæs, Viktoria; Elvsåshagen, Torbjørn; Westlye, Lars Tjelta; Høegh, Margrethe Collier; Haram, Marit & Werner, Maren Caroline Frogner [Show all 14 contributors for this article] (2021). Telomeres are shorter and associated with number of suicide attempts in affective disorders. Journal of Affective Disorders. ISSN 0165-0327. 295, p. 1032–1039. doi: 10.1016/j.jad.2021.08.135.
-
Gutman, Boris A.; van Erp, Theo G.M.; Alpert, Kathryn I.; Ching, Christopher; Isaev, Dmitry & Ragothaman, Anjani [Show all 84 contributors for this article] (2021). A meta-analysis of deep brain structural shape and asymmetry abnormalities in 2,833 individuals with schizophrenia compared with 3,929 healthy volunteers via the ENIGMA Consortium. Human Brain Mapping. ISSN 1065-9471. doi: 10.1002/hbm.25625. Full text in Research Archive
-
Jalbrzikowski, Maria; Hayes, Rebecca A.; Wood, Stephen J.; Dorte, Nordholm; Zhou, Juan H & Fusar-Poli, Paolo [Show all 51 contributors for this article] (2021). Association of Structural Magnetic Resonance Imaging Measures With Psychosis Onset in Individuals at Clinical High Risk for Developing Psychosis: An ENIGMA Working Group Mega-analysis. JAMA psychiatry. ISSN 2168-6238. 78(7), p. 753–766. doi: 10.1001/jamapsychiatry.2021.0638.
-
Sønderby, Ida Elken; Ching, Christopher R. K.; Thomopoulos, Sophia I.; van der Meer, Dennis; Sun, Daqiang & Villalon-Reina, Julio E. [Show all 52 contributors for this article] (2021). Effects of copy number variations on brain structure and risk for psychiatric illness: Large-scale studies from the ENIGMA working groups on CNVs. Human Brain Mapping. ISSN 1065-9471. doi: 10.1002/hbm.25354. Full text in Research Archive
-
Engh, John; Ueland, Thor; Agartz, Ingrid; Andreou, Dimitrios; Aukrust, Pål & Boye, Birgitte [Show all 27 contributors for this article] (2021). Plasma Levels of the Cytokines B Cell-Activating Factor (BAFF) and A Proliferation-Inducing Ligand (APRIL) in Schizophrenia, Bipolar, and Major Depressive Disorder: A Cross Sectional, Multisite Study. Schizophrenia Bulletin. ISSN 0586-7614. p. 1–10. doi: 10.1093/schbul/sbab106.
-
Elvsåshagen, Torbjørn; Shadrin, Alexey; Frei, Oleksandr; van der Meer, Dennis; Bahrami, Shahram & Kumar, Vinod J. [Show all 10 contributors for this article] (2021). The genetic architecture of the human thalamus and its overlap with ten common brain disorders. Nature Communications. ISSN 2041-1723. 12(1). doi: 10.1038/s41467-021-23175-z. Full text in Research Archive
-
Bjørnebekk, Astrid; Kaufmann, Tobias; Hauger, Lisa Evju; Klonteig, Sandra; Hullstein, Ingunn Riise & Westlye, Lars Tjelta (2021). Long-term Anabolic–Androgenic Steroid Use Is Associated With Deviant Brain Aging. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging. ISSN 2451-9022. 6(5), p. 579–589. doi: 10.1016/j.bpsc.2021.01.001. Full text in Research Archive
-
Siafarikas, Nikias Ioannis; Alnæs, Dag; Monereo Sanchez, Jennifer; Lund, Martina J.; Selbæk, Geir & Korsnes, Maria Stylianou [Show all 13 contributors for this article] (2021). Neuropsychiatric symptoms and brain morphology in patients with mild cognitive impairment and Alzheimer's disease with dementia. International Psychogeriatrics. ISSN 1041-6102. 33(11), p. 1217–1228. doi: 10.1017/S1041610221000934.
-
Sønderby, Ida Elken; van der Meer, Dennis; Moreau, Clara; Kaufmann, Tobias; Walters, G. Bragi & Ellegaard, Maria [Show all 76 contributors for this article] (2021). 1q21.1 distal copy number variants are associated with cerebral and cognitive alterations in humans. Translational Psychiatry. ISSN 2158-3188. 11. doi: 10.1038/s41398-021-01213-0. Full text in Research Archive
-
de Lange, Ann-Marie Glasø; Kaufmann, Tobias; Quintana, Daniel; Winterton, Adriano; Andreassen, Ole Andreas & Westlye, Lars Tjelta [Show all 7 contributors for this article] (2021). Prominent health problems, socioeconomic deprivation, and higher brain age in lonely and isolated individuals: A population-based study. Behavioural Brain Research. ISSN 0166-4328. doi: 10.1016/j.bbr.2021.113510. Full text in Research Archive
-
O'Connell, Kevin S.; Sønderby, Ida Elken; Frei, Oleksandr; van der Meer, Dennis; Athanasiu, Lavinia & Smeland, Olav Bjerkehagen [Show all 13 contributors for this article] (2021). Association between complement component 4A expression, cognitive performance and brain imaging measures in UK Biobank. Psychological Medicine. ISSN 0033-2917. p. 1–11. doi: 10.1017/S0033291721000179. Full text in Research Archive
-
Høgestøl, Einar August; Ghezzo, Samuele; Nygaard, Gro Owren; Espeseth, Thomas; Sowa, Piotr & Beyer, Mona K. [Show all 10 contributors for this article] (2021). Functional connectivity in multiple sclerosis modelled as connectome stability: A 5-year follow-up study. Multiple Sclerosis. ISSN 1352-4585. p. 1–9. doi: 10.1177/13524585211030212. Full text in Research Archive
-
Sanders, Anne-Marthe; Richard, Geneviève; Kolskår, Knut-Kristian; Ulrichsen, Kristine Moe; Kaufmann, Tobias & Alnæs, Dag [Show all 11 contributors for this article] (2021). Linking objective measures of physical activity and capability with brain structure in healthy community dwelling older adults. NeuroImage: Clinical. ISSN 2213-1582. 31. doi: 10.1016/j.nicl.2021.102767. Full text in Research Archive
-
Wolfers, Thomas; Rokicki, Jaroslav; Alnæs, Dag; Berthet, Pierre; Agartz, Ingrid & Kia, Seyed Mostafa [Show all 14 contributors for this article] (2021). Replicating extensive brain structural heterogeneity in individuals with schizophrenia and bipolar disorder. Human Brain Mapping. ISSN 1065-9471. 42(8), p. 2546–2555. doi: 10.1002/hbm.25386. Full text in Research Archive
-
Chen, Jiayu; Li, Xiang; Calhoun, Vince D.; Turner, Jessica A.; van Erp, Theo G.M. & Wang, Lei [Show all 16 contributors for this article] (2021). Sparse deep neural networks on imaging genetics for schizophrenia case–control classification. Human Brain Mapping. ISSN 1065-9471. 42(8), p. 2556–2568. doi: 10.1002/hbm.25387. Full text in Research Archive
-
Cheng, Weiqiu; Frei, Oleksandr; van der Meer, Dennis; Wang, Yunpeng; O`Connell, Kevin & Chu, Yunhan [Show all 20 contributors for this article] (2021). Genetic Association Between Schizophrenia and Cortical Brain Surface Area and Thickness. JAMA psychiatry. ISSN 2168-6238. 78(9), p. 1020–1030. doi: 10.1001/jamapsychiatry.2021.1435. Full text in Research Archive
-
Norbom, Linn Christin Bonaventure; Ferschmann, Lia; Parker, Nadine; Agartz, Ingrid; Andreassen, Ole Andreas & Paus, Tomas [Show all 8 contributors for this article] (2021). New insights into the dynamic development of the cerebral cortex in childhood and adolescence: Integrating macro- and microstructural MRI findings. Progress in Neurobiology. ISSN 0301-0082. 204, p. 1–19. doi: 10.1016/j.pneurobio.2021.102109. Full text in Research Archive
-
Gurholt, Tiril Pedersen; Kaufmann, Tobias; Frei, Oleksandr; Alnæs, Dag; Haukvik, Unn Kristin H. & van der Meer, Dennis [Show all 17 contributors for this article] (2021). Population-based body–brain mapping links brain morphology with anthropometrics and body composition. Translational Psychiatry. ISSN 2158-3188. doi: 10.1038/s41398-021-01414-7. Full text in Research Archive
-
Ulrichsen, Kristine Moe; Kolskår, Knut-Kristian; Richard, Geneviève; Alnæs, Dag; Dørum, Erlend Solberg & Sanders, Anne-Marthe [Show all 13 contributors for this article] (2021). Structural brain disconnectivity mapping of post-stroke fatigue. NeuroImage: Clinical. ISSN 2213-1582. 30. doi: 10.1016/j.nicl.2021.102635. Full text in Research Archive
-
Voldsbekk, Irene; Barth, Claudia; Maximov, Ivan I.; Kaufmann, Tobias; Beck, Dani & Richard, Genevive [Show all 9 contributors for this article] (2021). A history of previous childbirths is linked to women's white matter brain age in midlife and older age. Human Brain Mapping. ISSN 1065-9471. p. 1–15. doi: 10.1002/hbm.25553. Full text in Research Archive
-
Hellstrøm, Torgeir; Andelic, Nada; de Lange, Ann-Marie Glasø; Helseth, Eirik; Eiklid, Kristin Louise & Westlye, Lars Tjelta (2021). Apolipoprotein ɛ4 Status and Brain Structure 12 Months after Mild Traumatic Injury: Brain Age Prediction Using Brain Morphometry and Diffusion Tensor Imaging. Journal of Clinical Medicine. ISSN 2077-0383. 10(3). doi: 10.3390/jcm10030418. Full text in Research Archive
-
Maximov, Ivan; van der Meer, Dennis; de Lange, Ann-Marie Glasø; Kaufmann, Tobias; Shadrin, Alexey A. & Frei, Oleksandr [Show all 8 contributors for this article] (2021). Fast qualitY conTrol meThod foR derIved diffUsion Metrics (YTTRIUM) in big data analysis: U.K. Biobank 18,608 example. Human Brain Mapping. ISSN 1065-9471. doi: 10.1002/hbm.25424. Full text in Research Archive
-
Roelfs, Daniel; Alnæs, Dag; Frei, Oleksandr; van der Meer, Dennis; Smeland, Olav Bjerkehagen & Andreassen, Ole Andreas [Show all 8 contributors for this article] (2021). Phenotypically independent profiles relevant to mental health are genetically correlated. Translational Psychiatry. ISSN 2158-3188. 11(1). doi: 10.1038/s41398-021-01313-x. Full text in Research Archive Show summary
-
Voldsbekk, Irene; Groote, Inge Rasmus; Zak, Nathalia; Roelfs, Daniël Thomas Heimen; Geier, Oliver & Due-Tønnessen, Paulina [Show all 14 contributors for this article] (2021). Sleep and sleep deprivation differentially alter white matter microstructure: A mixed model design utilising advanced diffusion modelling. NeuroImage. ISSN 1053-8119. 226. doi: 10.1016/j.neuroimage.2020.117540. Full text in Research Archive
-
Hauger, Lisa Evju; Westlye, Lars Tjelta & Bjørnebekk, Astrid (2020). Anabolic androgenic steroid dependence is associated with executive dysfunction. Drug and Alcohol Dependence. ISSN 0376-8716. 208:107874, p. 1–8. doi: 10.1016/j.drugalcdep.2020.107874. Full text in Research Archive
-
Alnæs, Dag; Kaufmann, Tobias; Marquand, Andre; Smith, Stephen M. & Westlye, Lars Tjelta (2020). Patterns of sociocognitive stratification and perinatal risk in the child brain. Proceedings of the National Academy of Sciences of the United States of America. ISSN 0027-8424. 117(22). doi: 10.1073/pnas.2001517117.
-
Olsen, Alexander; Babikian, Talin; Bigler, Erin D.; Caeyenberghs, Karen; Conde, Virginia & Dams-O’Connor, Kristen [Show all 37 contributors for this article] (2020). Toward a global and reproducible science for brain imaging in neurotrauma: the ENIGMA adult moderate/severe traumatic brain injury working group. Brain Imaging and Behavior. ISSN 1931-7557. p. 1–29. doi: 10.1007/s11682-020-00313-7. Full text in Research Archive
-
Juvodden, Hilde Therese; Viken, Marte Kathrine; Nordstrand, Sebjørg Elizabeth Hesla; Viste, Rannveig; Westlye, Lars Tjelta & Thorsby, Per Medbøe [Show all 8 contributors for this article] (2020). HLA and sleep parameter associations in post-H1N1 narcolepsy type 1 patients and first-degree relatives. Sleep. ISSN 0161-8105. 43(3), p. 1–11. doi: 10.1093/sleep/zsz239. Full text in Research Archive
-
Dørum, Erlend Solberg; Kaufmann, Tobias; Alnæs, Dag; Richard, Geneviève; Kolskår, Knut-Kristian & Engvig, Andreas [Show all 11 contributors for this article] (2020). Functional brain network modeling in sub-acute stroke patients and healthy controls during rest and continuous attentive tracking. Heliyon. ISSN 2405-8440. 6:e04854(9), p. 1–11. doi: 10.1016/j.heliyon.2020.e04854. Full text in Research Archive
-
Valstad, Mathias; Moberget, Torgeir; Roelfs, Daniël Thomas Heimen; Slapø, Nora Berz; Timpe, Clara Marie Fides & Beck, Dani [Show all 18 contributors for this article] (2020). Experience-dependent modulation of the visual evoked potential: Testing effect sizes, retention over time, and associations with age in 415 healthy individuals. NeuroImage. ISSN 1053-8119. doi: 10.1016/j.neuroimage.2020.117302. Full text in Research Archive
-
Wierenga, Lara M.; Doucet, Gaëlle E.; Dima, Danai; Agartz, Ingrid; Aghajani, Moji & Akudjedu, Theophilus N. [Show all 50 contributors for this article] (2020). Greater male than female variability in regional brain structure across the lifespan. Human Brain Mapping. ISSN 1065-9471. doi: 10.1002/hbm.25204. Full text in Research Archive
-
Schwarz, Emanuel; Alnæs, Dag; Andreassen, Ole Andreas; Cao, Han; Chen, Junfang & Degenhardt, Franziska [Show all 27 contributors for this article] (2020). Identifying multimodal signatures underlying the somatic comorbidity of psychosis: the COMMITMENT roadmap. Molecular Psychiatry. ISSN 1359-4184. doi: 10.1038/s41380-020-00915-z. Full text in Research Archive
-
Hofer, Edith; Roshchupkin, Gennady V.; Adams, Hieab H H; Knol, Maria J.; Lin, Honghuang & Li, Shuo [Show all 51 contributors for this article] (2020). Genetic correlations and genome-wide associations of cortical structure in general population samples of 22,824 adults. Nature Communications. ISSN 2041-1723. 11. doi: 10.1038/s41467-020-18367-y. Full text in Research Archive
-
Grasby, Katrina L.; Jahanshad, Neda; Painter, Jodie N; Colodro-Conde, Lucía; Bralten, Janita & Hibar, DP [Show all 50 contributors for this article] (2020). The genetic architecture of the human cerebral cortex. Science. ISSN 0036-8075. 367(6484). doi: 10.1126/science.aay6690. Full text in Research Archive
-
Leu, Costin; Richardson, Tom G.; Kaufmann, Tobias; van der Meer, Dennis; Andreassen, Ole Andreas & Westlye, Lars Tjelta [Show all 9 contributors for this article] (2020). Pleiotropy of polygenic factors associated with focal and generalized epilepsy in the general population. PLOS ONE. ISSN 1932-6203. 15(4). doi: 10.1371/journal.pone.0232292. Full text in Research Archive
-
Kolskår, Knut-Kristian; Richard, Geneviève; Alnæs, Dag; Dørum, Erlend Solberg; Sanders, Anne-Marthe & Ulrichsen, Kristine Moe [Show all 10 contributors for this article] (2020). Reliability, sensitivity, and predictive value of fMRI during multiple object tracking as a marker of cognitive training gain in combination with tDCS in stroke survivors. Human Brain Mapping. ISSN 1065-9471. doi: 10.1002/hbm.25284. Full text in Research Archive
-
Ching, Christopher R. K.; Hibar, Derrek P.; Gurholt, Tiril Pedersen; Nunes, Abraham; Thomopoulos, Sophia I. & Abé, Chritsoph [Show all 51 contributors for this article] (2020). What we learn about bipolar disorder from large-scale neuroimaging: Findings and future directions from the ENIGMA Bipolar Disorder Working Group. Human Brain Mapping. ISSN 1065-9471. doi: 10.1002/hbm.25098. Full text in Research Archive
-
Winterton, Adriano; Westlye, Lars Tjelta; Steen, Nils Eiel; Andreassen, Ole Andreas & Quintana, Daniel (2020). Improving the precision of intranasal oxytocin research. Nature Human Behaviour. ISSN 2397-3374. p. 1–10. doi: 10.1038/s41562-020-00996-4.
-
Haukvik, Unn Kristin H.; Gurholt, Tiril Pedersen; Nerland, Stener; Elvsåshagen, Torbjørn; Akudjedu, Theophilus N. & Alda, Martin [Show all 97 contributors for this article] (2020). In vivo hippocampal subfield volumes in bipolar disorder—A mega‐analysis from The Enhancing Neuro Imaging Genetics through Meta‐Analysis Bipolar Disorder Working Group. Human Brain Mapping. ISSN 1065-9471. p. 1–14. doi: 10.1002/hbm.25249. Full text in Research Archive
-
Rokicki, Jaroslav; Wolfers, Thomas; Nordhøy, Wibeke; Tesli, Natalia; Quintana, Daniel & Alnæs, Dag [Show all 20 contributors for this article] (2020). Multimodal imaging improves brain age prediction and reveals distinct abnormalities in patients with psychiatric and neurological disorders. Human Brain Mapping. ISSN 1065-9471. 42(6), p. 1714–1726. doi: 10.1002/hbm.25323. Full text in Research Archive
-
Elvsåshagen, Torbjørn; Bahrami, Shahram; van der Meer, Dennis; Agartz, Ingrid; Alnæs, Dag & Barch, Deanna M. [Show all 76 contributors for this article] (2020). The genetic architecture of human brainstem structures and their involvement in common brain disorders. Nature Communications. ISSN 2041-1723. 11. doi: 10.1038/s41467-020-17376-1. Full text in Research Archive
-
Anatürk, Melis; Kaufmann, Tobias; Cole, James H.; Suri, Sana; Griffanti, Ludovica & Zsoldos, Enikő [Show all 12 contributors for this article] (2020). Prediction of brain age and cognitive age: Quantifying brain and cognitive maintenance in aging. Human Brain Mapping. ISSN 1065-9471. doi: 10.1002/hbm.25316. Full text in Research Archive
-
Chen, Junfang; Cao, Han; Kaufmann, Tobias; Westlye, Lars Tjelta; Tost, Heike & Meyer-Lindenberg, Andreas [Show all 7 contributors for this article] (2020). Identification of reproducible BCL11A alterations in schizophrenia through individual-level prediction of coexpression. Schizophrenia Bulletin. ISSN 0586-7614. 46(5), p. 1165–1171. doi: 10.1093/schbul/sbaa047. Full text in Research Archive
-
Ulrichsen, Kristine Moe; Alnæs, Dag; Kolskår, Knut-Kristian; Richard, Geneviève; Sanders, Anne-Marthe & Dørum, Erlend Solberg [Show all 11 contributors for this article] (2020). Dissecting the cognitive phenotype of post-stroke fatigue using computerized assessment and computational modeling of sustained attention. European Journal of Neuroscience. ISSN 0953-816X. 52(7), p. 3828–3845. doi: 10.1111/ejn.14861. Full text in Research Archive
-
Richard, Geneviève; Petersen, Anders; Ulrichsen, Kristine Moe; Kolskår, Knut-Kristian; Alnæs, Dag & Sanders, Anne-Marthe [Show all 10 contributors for this article] (2020). TVA-based modeling of short-term memory capacity, speed of processing and perceptual threshold in chronic stroke patients undergoing cognitive training: Case-control differences, reliability, and associations with cognitive performance. PeerJ. ISSN 2167-8359. 8:e9948, p. 1–21. doi: 10.7717/peerj.9948. Full text in Research Archive
-
Winterton, Adriano; Rødevand, Linn ; Westlye, Lars Tjelta; Steen, Nils Eiel; Andreassen, Ole Andreas & Quintana, Daniel (2020). Associations of loneliness and social isolation with cardiovascular and metabolic health: A systematic review and meta-analysis protocol. Systematic Reviews. ISSN 2046-4053. 9(1). doi: 10.1186/s13643-020-01369-8. Full text in Research Archive
-
Kia, Seyed Mostafa; Huijsdens, Hester; Dinga, Richard; Wolfers, Thomas; Mennes, Maarten & Andreassen, Ole Andreas [Show all 9 contributors for this article] (2020). Hierarchical bayesian regression for multi-site normative modeling of neuroimaging data. Lecture Notes in Computer Science (LNCS). ISSN 0302-9743. 12267, p. 699–709. doi: 10.1007/978-3-030-59728-3_68.
-
Beck, Dani; de Lange, Ann-Marie Glasø; Maximov, Ivan; Richard, Geneviève; Andreassen, Ole Andreas & Nordvik, Jan E. [Show all 7 contributors for this article] (2020). White matter microstructure across the adult lifespan: A mixed longitudinal and cross-sectional study using advanced diffusion models and brain-age prediction. NeuroImage. ISSN 1053-8119. 224:117441, p. 1–14. doi: 10.1016/j.neuroimage.2020.117441. Full text in Research Archive
-
Koenig, Julian; Abler, Birgit; Agartz, Ingrid; Åkerstedt, Torbjørn; Andreassen, Ole Andreas & Anthony, Mia [Show all 83 contributors for this article] (2020). Cortical thickness and resting‐state cardiac function across the lifespan: A cross‐sectional pooled mega‐analysis. Psychophysiology. ISSN 0048-5772. doi: 10.1111/psyp.13688. Full text in Research Archive Show summary
-
Benjamin, Silje Beatrice Rognås; Valstad, Mathias; Elvsåshagen, Torbjørn; Jönsson, Erik Gunnar; Moberget, Torgeir & Winterton, Adriano [Show all 14 contributors for this article] (2020). Heart rate variability is associated with disease severity in psychosis spectrum disorders. Progress in Neuro-psychopharmacology and Biological Psychiatry. ISSN 0278-5846. 00:110108, p. 1–8. doi: 10.1016/j.pnpbp.2020.110108. Full text in Research Archive
-
Còrdova Palomera, Aldo; van der Meer, Dennis; Kaufmann, Tobias; Bettella, Francesco; Wang, Yunpeng & Alnæs, Dag [Show all 40 contributors for this article] (2020). Genetic control of variability in subcortical and intracranial volumes. Molecular Psychiatry. ISSN 1359-4184. p. 1–8. doi: 10.1038/s41380-020-0664-1. Full text in Research Archive
-
van der Meer, Dennis; Frei, Oleksandr; Kaufmann, Tobias; Shadrin, Alexey A.; Devor, Anna & Smeland, Olav Bjerkehagen [Show all 12 contributors for this article] (2020). Understanding the genetic determinants of the brain with MOSTest. Nature Communications. ISSN 2041-1723. 11:3512, p. 1–9. doi: 10.1038/s41467-020-17368-1.
-
de Lange, Ann-Marie Glasø; Anatürk, Melis; Suri, Sana; Kaufmann, Tobias; Cole, James H. & Griffanti, Ludovica [Show all 13 contributors for this article] (2020). Multimodal brain-age prediction and cardiovascular risk: The Whitehall II MRI sub-study. NeuroImage. ISSN 1053-8119. 222. doi: 10.1016/j.neuroimage.2020.117292.
-
Norbom, Linn Christin Bonaventure; Rokicki, Jaroslav; van der Meer, Dennis; Alnæs, Dag; Doan, Nhat Trung & Moberget, Torgeir [Show all 10 contributors for this article] (2020). Testing relationships between multimodal modes of brain structural variation and age, sex and polygenic scores for neuroticism in children and adolescents. Translational Psychiatry. ISSN 2158-3188. 10(251). doi: 10.1038/s41398-020-00931-1. Full text in Research Archive
-
Norbom, Linn Christin Bonaventure; Rokicki, Jaroslav; Alnæs, Dag; Kaufmann, Tobias; Doan, Nhat Trung & Andreassen, Ole Andreas [Show all 8 contributors for this article] (2020). Maturation of cortical microstructure and cognitive development in childhood and adolescence: A T1w/T2w ratio MRI study. Human Brain Mapping. ISSN 1065-9471. 41(16), p. 4676–4690. doi: 10.1002/hbm.25149. Full text in Research Archive
-
de Lange, Ann-Marie Glasø; Barth, Claudia; Kaufmann, Tobias; Maximov, Ivan; van der Meer, Dennis & Agartz, Ingrid [Show all 7 contributors for this article] (2020). Women's brain aging: effects of sex-hormone exposure, pregnancies, and genetic risk for Alzheimer's disease. Human Brain Mapping. ISSN 1065-9471. p. 1–10. doi: 10.1002/hbm.25180. Full text in Research Archive
-
Tønnesen, Siren; Kaufmann, Tobias; de Lange, Ann-Marie Glasø; Richard, Geneviève; Doan, Nhat Trung & Alnæs, Dag [Show all 33 contributors for this article] (2020). Brain age prediction reveals aberrant brain white matter in schizophrenia and bipolar disorder: A multisample diffusion tensor imaging study. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging. ISSN 2451-9022. 5(12), p. 1095–1103. doi: 10.1016/j.bpsc.2020.06.014. Full text in Research Archive
-
de Lange, Ann-Marie Glasø; Barth, Claudia; Kaufmann, Tobias; Anatürk, Melis; Suri, Sana & Ebmeier, Klaus [Show all 7 contributors for this article] (2020). The maternal brain: region-specific patterns of brain aging are traceable decades after childbirth. Human Brain Mapping. ISSN 1065-9471. doi: 10.1002/hbm.25152. Full text in Research Archive
-
Lund, Martina Jonette; Alnæs, Dag; Schwab, Simon; van der Meer, Dennis; Andreassen, Ole Andreas & Westlye, Lars Tjelta [Show all 7 contributors for this article] (2020). Differences in directed functional brain connectivity related to age, sex and mental health. Human Brain Mapping. ISSN 1065-9471. 41(15), p. 4173–4186. doi: 10.1002/hbm.25116. Full text in Research Archive
-
Liew, Sook-Lei; Zavaliangos-Petropulu, Artemis; Jahanshad, Neda; Lang, Catherine E.; Hayward, Kathryn S. & Lohse, Keith R. [Show all 67 contributors for this article] (2020). The ENIGMA Stroke Recovery Working Group: Big data neuroimaging to study brain - behavior relationships after stroke. Human Brain Mapping. ISSN 1065-9471. p. 1–20. doi: 10.1002/hbm.25015. Full text in Research Archive
-
van der Meer, Dennis; Frei, Oleksandr; Kaufmann, Tobias; Chen, Chi-Hua; Thompson, Wesley K. & O'Connell, Kevin S. [Show all 11 contributors for this article] (2020). Quantifying the polygenic architecture of the human cerebral cortex: Extensive genetic overlap between cortical thickness and surface area. Cerebral Cortex. ISSN 1047-3211. 30(10), p. 5597–5603. doi: 10.1093/cercor/bhaa146. Full text in Research Archive
-
Izzo, Jessica; Andreassen, Ole Andreas; Westlye, Lars Tjelta & van der Meer, Dennis (2019). The association between hippocampal subfield volumes in mild cognitive impairment and conversion to Alzheimer’s disease. Brain Research. ISSN 0006-8993. p. 1–7. doi: 10.1016/j.brainres.2019.146591.
-
Richard, Geneviève; Kolskår, Knut-Kristian; Ulrichsen, Kristine Moe; Kaufmann, Tobias; Alnæs, Dag & Sanders, Anne-Marthe [Show all 12 contributors for this article] (2019). Brain age prediction in stroke patients: Highly reliable but limited sensitivity to cognitive performance and response to cognitive training. NeuroImage: Clinical. ISSN 2213-1582. 25, p. 1–11. doi: 10.1016/j.nicl.2019.102159. Full text in Research Archive
-
Satizabal, Claudia L.; Adams, Hieab H.H.; Hibar, Derrek; White, Charles C.; Knol, Maria J. & Stein, Jason L. [Show all 289 contributors for this article] (2019). Genetic architecture of subcortical brain structures in 38,851 individuals. Nature Genetics. ISSN 1061-4036. 51, p. 1624–1636. doi: 10.1038/s41588-019-0511-y. Full text in Research Archive
-
Ousdal, Olga Therese; Kaufmann, Tobias; Kolskår, Knut-Kristian; Vik, Alexandra; Wehling, Eike & Lundervold, Astri [Show all 8 contributors for this article] (2019). Longitudinal stability of the brain functional connectome is associated with episodic memory performance in aging. Human Brain Mapping. ISSN 1065-9471. 41, p. 697–709. doi: 10.1002/hbm.24833. Full text in Research Archive
-
Voldsbekk, Irene; Lund, Martina Jonette; Kaufmann, Tobias; Fernandez-Cabello, Sara; Kjelkenes, Rikka & Dahl, Andreas [Show all 9 contributors for this article] (2022). Cross-Diagnostic Patterns of Socio-Cognitive Traits in the Developing Brain of Children and Adolescents.
-
Maximov, Ivan; van der Meer, Dennis; de Lange, Ann-Marie Glasø; Kaufmann, Tobias; Shadrin, Alexey & Frei, Oleksandr [Show all 8 contributors for this article] (2021). YTTRIUM: QC algorithm for the processed diffusion maps in UK Biobank 18608 sample.
-
Maximov, Ivan; van der Meer, Dennis; de Lange, Ann Marie; Kaufmann, Tobias & Westlye, Lars Tjelta (2021). Probing human cortical microstructure using diffusion MRI: insights from N = 17,646 individuals of the UK Biobank.
-
Alnæs, Dag & Westlye, Lars Tjelta (2019). Factors Associated with Brain Heterogeneity in Schizophrenia - Reply. JAMA psychiatry. ISSN 2168-6238. 76(11), p. 1211–1212. doi: 10.1001/jamapsychiatry.2019.1855.