Athanasia Monika Mowinckel

Researcher - Livsløpsendringer i hjerne og kognisjon

Norwegian version of this page

Email a.m.mowinckel@psykologi.uio.no

Phone +47 22845022

Room A04-006

Available hours Tuesday: 11-16, Thursday: 11-16

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Visiting address Harald Schjelderups hus Forskningsveien 3A 0373 Oslo

Postal address Postboks 1094 Blindern 0317 Oslo

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Academic Interests

I am part of the cognitive and neuroscience division of the Department of Psychology. My PhD project is on decision making in adult ADHD, and how stimulant medication influences the decision making process in this patient group. I focus especially on reward based decisions (monetary rewards). In addition to this, I will try to see how adults with ADHD activate different brain areas during decisions and whether this is different to healthy controls, and how this process is altered by medication. This part of the project is done in collaboration with The Intervention Center at oslo University Hospital on their 3 Tesla Phillips scanner. As both ADHD and decision making are related to the catecholamines dopamine and serotonin, I am also generally interested in how these neurotransmitters influence our behaviour.

My PhD is part of a larger project with several researchers (please see panel to the right for link), and we cooperate with an ADHD clinic in Tønsberg, which is part of Vestre Viken Hospital Trust.

Apart from my PhD project, I am also very interested in instrinsic brain activation, measured through fMRI. Task-based fMRI looks for changes in bloodflow only equal to about 1%, what the brain does with the remaining 99% is something that has gained increasing interest in the neuroscientific field the last 10 years. This "resting state" can hopefully give us indications of how the brain is functionally organised, in comparison to the structural connectivity which is easier to measure. The hope is being able to use this intrinsic fMRI procedure to help diagnose functional problems, without patients needing to understand and remember complex experimental paradims.

Teaching

Higher education and employment history

I completed my Bachelor's (under-graduate) in Cognitive Psychology in 2009, and continued to take my Master's degree (2-year post-graduate) in Cognitive neuroscience right after this, both at the University of Oslo. My Master's project was about age-realted changes in resting state patterns in a large sample of adults spanning 20 - 80 years of age.

I worked for several years at Vestre Viken Hospital Trust, Blakstad hospital, as a community worker in a department with mainly schizophrenics and persons with dual diagnosis problems. Additionally, I have worked for some years as a research assistent and a seminar leader at the University of Oslo.

Tags: Cognitive psychology, Neuroscience, Neuropsychology

Vidal-Piñeiro, Didac; Wang, Yunpeng; Krogsrud, Stine Kleppe; Amlien, Inge; Baaré, William FC & Bartres-Faz, David [Show all 31 contributors for this article] (2021). Individual variations in ‘brain age’ relate to early-life factors more than to longitudinal brain change. eLIFE. ISSN 2050-084X. 10. doi: 10.7554/eLife.69995. Full text in Research Archive
Fjell, Anders Martin; Grydeland, Håkon; Wang, Yunpeng; Amlien, Inge; Bartrés-Faz, David & Brandmaier, Andreas M. [Show all 24 contributors for this article] (2021). The genetic organization of longitudinal subcortical volumetric change is stable throughout the lifespan running title: Genetics of subcortical lifespan change. eLIFE. ISSN 2050-084X. 10, p. 1–22. doi: 10.7554/eLife.66466.
Walhovd, Kristine Beate; Fjell, Anders Martin; Wang, Yunpeng; Amlien, Inge; Mowinckel, Athanasia Monika & Lindenberger, Ulman [Show all 29 contributors for this article] (2021). Education and income show heterogeneous relationships to lifespan brain and cognitive differences across European and US cohorts. Cerebral Cortex. ISSN 1047-3211. 32(4), p. 839–854. doi: 10.1093/cercor/bhab248. Full text in Research Archive
Krogsrud, Stine Kleppe; Mowinckel, Athanasia Monika; Sederevicius, Donatas; Vidal-Piñeiro, Didac; Amlien, Inge Kasbohm & Wang, Yunpeng [Show all 9 contributors for this article] (2021). Relationships between apparent cortical thickness and working memory across the lifespan - Effects of genetics and socioeconomic status. Developmental Cognitive Neuroscience. ISSN 1878-9293. 51, p. 1–11. doi: 10.1016/j.dcn.2021.100997.
Roe, James Michael; Vidal-Piñeiro, Didac; Sørensen, Øystein; Brandmaier, Andreas M.; Düzel, Sandra & Gonzalez, Hector A. [Show all 18 contributors for this article] (2021). Asymmetric thinning of the cerebral cortex across the adult lifespan is accelerated in Alzheimer’s disease. Nature Communications. ISSN 2041-1723. 12:721, p. 1–11. doi: 10.1038/s41467-021-21057-y.
Sørensen, Øystein; Brandmaier, Andreas M.; Macià, Dídac; Ebmeier, Klaus; Ghisletta, Paolo & Kievit, Rogier A. [Show all 10 contributors for this article] (2021). Meta-analysis of generalized additive models in neuroimaging studies. NeuroImage. ISSN 1053-8119. doi: 10.1016/j.neuroimage.2020.117416.
Walhovd, Kristine B; Bråthen, Anne Cecilie Sjøli; Panizzon, Matthew S.; Mowinckel, Athanasia Monika; Sørensen, Øystein & de Lange, Ann-Marie Glasø [Show all 11 contributors for this article] (2020). Within-session verbal learning slope is predictive of lifespan delayed recall, hippocampal volume, and memory training benefit, and is heritable. Scientific Reports. ISSN 2045-2322. 10, p. 1–13. doi: 10.1038/s41598-020-78225-1. Full text in Research Archive
Danielsen, Vilde Marie; Vidal-Piñeiro, Didac; Mowinckel, Athanasia Monika; Sederevicius, Donatas; Fjell, Anders Martin & Walhovd, Kristine B [Show all 7 contributors for this article] (2020). Lifespan trajectories of relative corpus callosum thickness: Regional differences and cognitive relevance. Cortex. ISSN 0010-9452. 130, p. 127–141. doi: 10.1016/j.cortex.2020.05.020.
Gorbach, Tetiana; Pudas, Sara; Bartrés-Faz, David; Brandmaier, Andreas M.; Düzel, Sandra & Henson, Rik [Show all 17 contributors for this article] (2020). Longitudinal association between hippocampus atrophy and episodic‐memory decline in non‐demented APOE ε4 carriers. Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. ISSN 2352-8729. 12(1). doi: 10.1002/dad2.12110. Full text in Research Archive
Fjell, Anders Martin; Sørensen, Øystein; Amlien, Inge Kasbohm; Bartrés-Faz, David; Brandmaier, Andreas M. & Buchmann, Nikolaus [Show all 32 contributors for this article] (2020). Poor Self-Reported Sleep is Related to Regional Cortical Thinning in Aging but not Memory Decline-Results From the Lifebrain Consortium. Cerebral Cortex. ISSN 1047-3211. p. 1–17. doi: 10.1093/cercor/bhaa332.
Vidal-Piñeiro, Didac; Sneve, Markus Handal; Amlien, Inge Kasbohm; Grydeland, Håkon; Mowinckel, Athanasia Monika & Roe, James Michael [Show all 10 contributors for this article] (2020). The Functional Foundations of Episodic Memory Remain Stable Throughout the Lifespan. Cerebral Cortex. ISSN 1047-3211. doi: 10.1093/cercor/bhaa348. Full text in Research Archive
Vidal-Piñeiro, Didac; Parker, Nadine; Shin, Jean; French, Leon; Grydeland, Håkon & Jackowski, Andrea [Show all 14 contributors for this article] (2020). Cellular correlates of cortical thinning throughout the lifespan. Scientific Reports. ISSN 2045-2322. 10(1), p. 1–14. doi: 10.1038/s41598-020-78471-3. Full text in Research Archive
Mowinckel, Athanasia Monika & Vidal-Piñeiro, Didac (2020). Visualization of Brain Statistics With R Packages ggseg and ggseg3d. Advances in Methods and Practices in Psychological Science (AMPPS). ISSN 2515-2459. doi: 10.1177/2515245920928009.
Walhovd, Kristine B; Fjell, Anders Martin; Sørensen, Øystein; Mowinckel, Athanasia Monika; Reinbold, Céline Sonja & Idland, Ane-Victoria [Show all 12 contributors for this article] (2020). Genetic risk for Alzheimer disease predicts hippocampal volume through the human lifespan. Neurology: Genetics. ISSN 2376-7839. 6(5). doi: 10.1212/NXG.0000000000000506. Full text in Research Archive
Ljøsne, Isabelle Sylvie Budin; Friedman, Barbara Bodorkos; Suri, Sana; Solé-Padullés, Cristina; Düzel, Sandra & Drevon, Christian A [Show all 24 contributors for this article] (2020). The global brain health survey: Development of a multi-language survey of public views on brain health. Frontiers In Public Health. ISSN 2296-2565. 8:387, p. 1–13. doi: 10.3389/fpubh.2020.00387. Full text in Research Archive
Fjell, Anders Martin; Sørensen, Øystein; Amlien, Inge Kasbohm; Bartrés-Faz, David; Bros, Didac Macia & Buchmann, Nikolaus [Show all 28 contributors for this article] (2019). Self-reported sleep relates to hippocampal atrophy across the adult lifespan – results from the Lifebrain consortium. Sleep. ISSN 0161-8105. doi: 10.1093/sleep/zsz280. Full text in Research Archive
Fjell, Anders Martin; Sneve, Markus Handal; Sederevicius, Donatas; Sørensen, Øystein; Krogsrud, Stine Kleppe & Mowinckel, Athanasia Monika [Show all 7 contributors for this article] (2019). Volumetric and microstructural regional changes of the hippocampus underlying development of recall performance after extended retention intervals. Developmental Cognitive Neuroscience. ISSN 1878-9293. 40:100723, p. 1–12. doi: 10.1016/j.dcn.2019.100723. Full text in Research Archive
Fjell, Anders Martin; Chen, Chi-Hua Chen; Sederevicius, Donatas; Sneve, Markus Handal; Grydeland, Håkon & Krogsrud, Stine Kleppe [Show all 17 contributors for this article] (2019). Continuity and discontinuity in human cortical development and change from embryonic stages to old age. Cerebral Cortex. ISSN 1047-3211. 29(9), p. 3879–3890. doi: 10.1093/cercor/bhy266. Full text in Research Archive
Vidal-Piñeiro, Didac; Sneve, Markus Handal; Nyberg, Lars; Mowinckel, Athanasia Monika; Sederevicius, Donatas & Walhovd, Kristine B [Show all 7 contributors for this article] (2019). Maintained Frontal Activity Underlies High Memory Function Over 8 Years in Aging. Cerebral Cortex. ISSN 1047-3211. 29(7), p. 3111–3123. doi: 10.1093/cercor/bhy177. Full text in Research Archive
Mowinckel, Athanasia Monika; Alnæs, Dag; Pedersen, Mads Lund; Ziegler, Sigurd; Fredriksen, Mats & Kaufmann, Tobias [Show all 10 contributors for this article] (2017). Increased default-mode variability is related to reduced task-performance and is evident in adults with ADHD. NeuroImage: Clinical. ISSN 2213-1582. 16, p. 369–382. doi: 10.1016/j.nicl.2017.03.008. Full text in Research Archive
Ziegler, Sigurd; Pedersen, Mads Lund; Mowinckel, Athanasia Monika & Biele, Guido (2016). Modelling ADHD: A review of ADHD theories through their predictions for computational models of decision-making and reinforcement learning. Neuroscience and Biobehavioral Reviews. ISSN 0149-7634. 71, p. 633–656. doi: 10.1016/j.neubiorev.2016.09.002.
Mowinckel, Athanasia Monika; Pedersen, Mads Lund; Eilertsen, Espen Moen & Biele, Guido (2015). A Meta-Analysis of Decision-Making and Attention in Adults With ADHD. Journal of Attention Disorders. ISSN 1087-0547. 19(5), p. 355–367. doi: 10.1177/1087054714558872. Show summary
Abstract Objective: Deficient reward processing has gained attention as an important aspect of ADHD, but little is known about reward-based decision-making (DM) in adults with ADHD. This article summarizes research on DM in adult ADHD and contextualizes DM deficits by comparing them to attention deficits. Method: Meta-analytic methods were used to calculate average effect sizes for different DM domains and continuous performance task (CPT) measures. Results: None of the 59 included studies (DM: 12 studies; CPT: 43; both: 4) had indications of publication bias. DM and CPT measures showed robust, small to medium effects. Large effect sizes were found for a drift diffusion model analysis of the CPT. Conclusion: The results support the existence of DM deficits in adults with ADHD, which are of similar magnitude as attention deficits. These findings warrant further examination of DM in adults with ADHD to improve the understanding of underlying neurocognitive mechanisms
Mowinckel, Athanasia Monika; Espeseth, Thomas & Westlye, Lars Tjelta (2012). Network-specific effects of age and in-scanner subject motion: A resting-state fMRI study of 238 healthy adults. NeuroImage. ISSN 1053-8119. 63(3), p. 1364–1373. doi: 10.1016/j.neuroimage.2012.08.004. Show summary
Cognitive aging is accompanied by a range of structural and functional differences in the brain, even in the absence of neurodegenerative disease. Functional magnetic resonance imaging (fMRI) studies have reported increased bilateral activation during task performance in elderly participants compared to their younger counterparts, particularly in frontal regions. Alterations have also been observed in the functional architecture of the resting brain, suggesting that aging is associated with changes in the organization of the networks of the brain. However, previous studies have largely focused on the default mode network, and little is known about the effects of age on other resting state-networks (RSNs). The aim of the present study was to investigate age-differences in resting state functional connectivity (RSFC) using fMRI data obtained during rest from 238 healthy participants aged 21–80 years. Using independent component analysis (ICA) and dual-regression, the results revealed age-related increases in RSFC across a range of RSNs, including task-positive networks in frontal and parietal regions. In contrast, age-related reductions in the default mode network and occipital visual networks were observed. Furthermore, whereas the effects of age on the various RSNs were found independent of age-related decreases in gray matter volume, sex and subject motion, we report strong positive and widespread effects of estimated subject motion on the RSFC across RSNs. The results provide support for the notion of network-specific effects in aging, manifested as increased tonic activation of task-positive networks, supporting higher-order cognitive functions and cognitive control, along with reduced task-negative default mode network and sensory visual networks during rest. The present results also corroborate recent evidence of strong influence of subject motion on estimated functional connectivity measures and strongly suggest that studies using RSFC measures as imaging phenotypes should adjust for individual differences in in-scanner subject motion.

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Roe, James Michael; Vidal-Piñeiro, Didac; Sørensen, Øystein; Brandmaier, Andreas M.; Düzel, Sandra & Gonzalez, Hector A. [Show all 78 contributors for this article] (2022). Author Correction: Asymmetric thinning of the cerebral cortex across the adult lifespan is accelerated in Alzheimer’s disease (Nature Communications, (2021), 12, 1, (721), 10.1038/s41467-021-21057-y). Nature Communications. ISSN 2041-1723. 13(1). doi: 10.1038/s41467-022-28514-2.
Mowinckel, Athanasia Monika (2021). R and the tidyverse.
Mowinckel, Athanasia Monika (2021). Make something random - learn something useful.
Mowinckel, Athanasia Monika (2021). Zhoosh up your ggplots .
Mowinckel, Athanasia Monika (2021). Advanced R use - package development in R .
Mowinckel, Athanasia Monika (2021). A different type of database - talk about LCBC data base .
Mowinckel, Athanasia Monika (2021). Talk on nettskjema R package.
Mowinckel, Athanasia Monika (2021). Talk on the LCBC ggseg R-package.
Mowinckel, Athanasia Monika (2020). Talk on gg-seg R package .
Mowinckel, Athanasia Monika (2020). Talk on the LCBC ggseg R-package.
Mowinckel, Athanasia Monika (2016). Re: Kronisk utmattelsessyndrom og erfaring med Lightning Process. Tidsskrift for Den norske legeforening. ISSN 0029-2001. 136(7).

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Published Aug. 27, 2012 11:31 AM - Last modified Feb. 4, 2020 11:33 AM

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