Pre- and postnatal environmental and genetic factors (completed)
- in relation to brain development in the Norwegian Mother and Child Cohort Study
About the project
The primary objective is to relate brain development by magnetic resonance imaging (MRI) to pre and postnatal circumstances and functioning in 700 children. Children aged 4-11 will be recruited through the Norwegian Mother and Child Cohort (MoBa) study and examined twice, a year apart. These data will become part of the MoBa database.
The aim is to establish a database of brain and behavioral measures to track neurocognitive development in children recruited trough the Norwegian Mother and Child Cohort Study (MoBa) undertaken by the Norwegian Institute of Public Health. Questionnaire and biological data were gathered pre- and postnatally for 100.000 children born 1999-2008 to illuminate public health issues. The primary objective of this subproject is to relate brain development by magnetic resonance imaging (MRI) to pre- and postnatal circumstances and functioning in 700 of the children, testing how genetic variations and pre- and postnatal environmental factors interact in the development of brain, cognition and coping in normal and at risk (preterm born) children. Children aged 4-11 will be recruited and scanned and assessed twice with cognitive and screening tests, a year apart. Normal variation in behavioral outcomes and consequences of health problems studied in MoBa, e.g. cognitive problems in children born prematurely (n=100) or with low birth weight are mediated by cerebral characteristics, and data on brain development will become part of the MoBa database.
The Research Council of Norway (Young talented researchers - FRIMEDBIO)