Linn Christin Bonaventure Norbom
Structural patterns of brain development
Clinical and genetic risk of psychosis
Structural brain alterations of sleep and sleep deprivation
Multimodal neuroimaging (sMRI, DTI, EEG, LICA)
I am a PhD candidate at the Cognitive and Clinical Neuropsychology group, Department of Psychology, University of Oslo, and the Norwegian Centre for Mental Disorders Research (NORMENT), Oslo University Hospital, Ullevål.
In my PhD project I intend to investigate structural neurodevelopmental patterns associated with clinical and genetic risk of psychosis. Novel neuroimaging methods such as grey and white matter intensity contrast will be employed in combination with more frequently used structural measures and multimodal neuroimaging data analyses will be performed using linked independent component analysis (LICA). Moreover, structural imaging data will be linked to both risk genes connected with brain myelination and polygenic risk scores.
Exploring the structural developmental processes of the brain is in addition to uncovering vital basic knowledge, also an important feat in order to uncover aberrant developmental patterns that may be associated with increased risk of severe mental illness.
Adolescence is a period of extensive maturational reorganisation across brain regions and also coincides with the onset period of most psychotic disorders. Although only about 3% of the general population will receive a psychotic disorder diagnosis, subclinical symptoms form a spectre within the general population. Moreover, children and adolescence with subclinical symptoms are at increased risk of progressing into a psychotic disorder at a later stage and accordingly, such expressions could at times be an early manifestation of the illness.
2011-2013 Master in Cognitive Neuroscience, Department of Psychology, University of Oslo
2007-2010 Bachelor in Cognitive Psychology, Department of Psychology, University of Oslo